Toward improved myocardial maturity in an organ-on-chip platform with immature cardiac myocytes

Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses

(2016) Nathaniel Huebsch et al.   Scientific Reports

Structural Phenotyping of Stem Cell-Derived Cardiomyocytes

(2015) Francesco Silvio Pasqualini et al.   Stem Cell Reports

Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications

(2015) Anurag Mathur et al.   Scientific Reports

Automated analysis of contractile force and Ca2+ transients in engineered heart tissue

(2014) Andrea Stoehr et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Matrix elasticity regulates the optimal cardiac myocyte shape for contractility

(2014) Megan L. McCain et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues

(2014) Megan L. McCain et al.   BIOMATERIALS

Engineering Adolescence

(2014) Xiulan Yang et al.   CIRCULATION RESEARCH

Approaching the in vitro clinical trial: engineering organs on chips

(2014) A. K. Capulli et al.   LAB ON A CHIP

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

3D bioprinting of tissues and organs

(2014) Sean V Murphy et al.   NATURE BIOTECHNOLOGY

Systematic Reviews of Animal Models: Methodology versus Epistemology

(2013) Ray Greek et al.   International Journal of Medical Sciences

Microfluidic heart on a chip for higher throughput pharmacological studies

(2013) Ashutosh Agarwal et al.   LAB ON A CHIP

Biowire: a platform for maturation of human pluripotent stem cell–derived cardiomyocytes

(2013) Sara S Nunes et al.   NATURE METHODS

Design and formulation of functional pluripotent stem cell-derived cardiac microtissues

(2013) N. Thavandiran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myocyte Shape Regulates Lateral Registry of Sarcomeres and Contractility

(2012) Po-Ling Kuo et al.   AMERICAN JOURNAL OF PATHOLOGY

Physiological aspects of cardiac tissue engineering

(2012) Thomas Eschenhagen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture

(2012) Adam W. Feinberg et al.   BIOMATERIALS

The contribution of cellular mechanotransduction to cardiomyocyte form and function

(2012) Sean P. Sheehy et al.   Biomechanics and Modeling in Mechanobiology

Design standards for engineered tissues

(2012) Janna C. Nawroth et al.   BIOTECHNOLOGY ADVANCES

Contractile Properties of Early Human Embryonic Stem Cell-Derived Cardiomyocytes: Beta-Adrenergic Stimulation Induces Positive Chronotropy and Lusitropy but Not Inotropy

(2012) Frank Pillekamp et al.   STEM CELLS AND DEVELOPMENT

Muscle on a chip: In vitro contractility assays for smooth and striated muscle

(2012) Anna Grosberg et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Terminal Differentiation, Advanced Organotypic Maturation, and Modeling of Hypertrophic Growth in Engineered Heart Tissue

(2011) Malte Tiburcy et al.   CIRCULATION RESEARCH

Hierarchical architecture influences calcium dynamics in engineered cardiac muscle

(2011) Terrence Pong et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Ensembles of engineered cardiac tissues for physiological and pharmacological study: Heart on a chip

(2011) Anna Grosberg et al.   LAB ON A CHIP

Mechanotransduction: the role of mechanical stress, myocyte shape, and cytoskeletal architecture on cardiac function

(2011) Megan L. McCain et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

A Microfabricated Platform to Measure and Manipulate the Mechanics of Engineered Cardiac Microtissues

(2011) Thomas Boudou et al.   TISSUE ENGINEERING PART A

Self-Organization of Muscle Cell Structure and Function

(2011) Anna Grosberg et al.   PLoS Computational Biology

Differential gene expressions in atrial and ventricular myocytes: insights into the road of applying embryonic stem cell-derived cardiomyocytes for future therapies

(2010) Sze Ying Ng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cardiac myocyte force development during differentiation and maturation

(2010) Jeffrey G. Jacot et al.   Annals of the New York Academy of Sciences

Biohybrid thin films for measuring contractility in engineered cardiovascular muscle

(2010) Patrick W. Alford et al.   BIOMATERIALS

Nuclear morphology and deformation in engineered cardiac myocytes and tissues

(2010) Mark-Anthony P. Bray et al.   BIOMATERIALS

Micropatterned matrix directs differentiation of human mesenchymal stem cells towards myocardial lineage

(2010) Chor Yong Tay et al.   EXPERIMENTAL CELL RESEARCH

Hypertrophic phenotype in cardiac cell assemblies solely by structural cues and ensuing self-organization

(2010) Chiung-yin Chung et al.   FASEB JOURNAL

Control of myocyte remodeling in vitro with engineered substrates

(2009) Nicholas A. Geisse et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Myofibrillar Architecture in Engineered Cardiac Myocytes

(2008) Kevin Kit Parker et al.   CIRCULATION RESEARCH

Cardiac myofibrillogenesis inside intact embryonic hearts

(2008) Aiping Du et al.   DEVELOPMENTAL BIOLOGY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Biomechanical ordering of dense cell populations

(2008) D. Volfson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiogenesis and the Complex Biology of Regenerative Cardiovascular Medicine

(2008) K. R. Chien et al.   SCIENCE

Sarcomere alignment is regulated by myocyte shape

(2008) Mark-Anthony Bray et al.   CELL MOTILITY AND THE CYTOSKELETON