Fecal transplantation and butyrate improve neuropathic pain, modify immune cell profile, and gene expression in the PNS of obese mice

Fecal microbiota transplantation improves metabolism and gut microbiome composition in db/db mice

(2020) Pei-pei Zhang et al.   ACTA PHARMACOLOGICA SINICA

Using MicrobiomeAnalyst for comprehensive statistical, functional, and meta-analysis of microbiome data

(2020) Jasmine Chong et al.   Nature Protocols

Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain

(2020) Xiaobing Yu et al.   Nature Communications

Promising Treatment for Type 2 Diabetes: Fecal Microbiota Transplantation Reverses Insulin Resistance and Impaired Islets

(2020) Hui Wang et al.   Frontiers in Cellular and Infection Microbiology

The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages

(2019) Julie Schulthess et al.   IMMUNITY

The role of short-chain fatty acids in microbiota–gut–brain communication

(2019) Boushra Dalile et al.   Nature Reviews Gastroenterology & Hepatology

The contribution of obesity to prescription opioid use in the United States

(2019) Andrew Stokes et al.   PAIN

Association Between Peripheral Neuropathy and Exposure to Oral Fluoroquinolone or Amoxicillin-Clavulanate Therapy

(2019) Daniel Morales et al.   JAMA Neurology

Normalizing HDAC2 Levels in the Spinal Cord Alleviates Thermal and Mechanical Hyperalgesia After Peripheral Nerve Injury and Promotes GAD65 and KCC2 Expression

(2019) Bihan Ouyang et al.   Frontiers in Neuroscience

Altered microbiome composition in individuals with fibromyalgia

(2019) Amir Minerbi et al.   PAIN

Effects of sodium butyrate on intestinal health and gut microbiota composition during intestinal inflammation progression in broilers

(2019) X Zou et al.   POULTRY SCIENCE

Inner Workings: How bacteria cause pain and what that reveals about the role of the nervous system

(2019) Amber Dance   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rational treatment of chemotherapy-induced peripheral neuropathy with capsaicin 8% patch: from pain relief towards disease modification

(2019) Praveen Anand et al.   Journal of Pain Research

Microbial Metabolism Modulates Antibiotic Susceptibility within the Murine Gut Microbiome

(2019) Damien J. Cabral et al.   Cell Metabolism

The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination

(2019) Christopher E. McMurran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating but not faecal short-chain fatty acids are related to insulin sensitivity, lipolysis and GLP-1 concentrations in humans

(2019) Mattea Müller et al.   Scientific Reports

Oxidized Lipids in Persistent Pain States

(2019) Tabea Osthues et al.   Frontiers in Pharmacology

Gut-Innervating Nociceptor Neurons Regulate Peyer’s Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense

(2019) Nicole Y. Lai et al.   CELL

High fiber dietary and sodium butyrate attenuate experimental autoimmune hepatitis through regulation of immune regulatory cells and intestinal barrier

(2018) En-De Hu et al.   CELLULAR IMMUNOLOGY

Potential of butyrate to influence food intake in mice and men

(2018) Kristina S Fluitman et al.   GUT

Immune regulation by microbiome metabolites

(2018) Chang H. Kim   IMMUNOLOGY

Reducing CXCR4-mediated nociceptor hyperexcitability reverses painful diabetic neuropathy

(2018) Nirupa D. Jayaraj et al.   JOURNAL OF CLINICAL INVESTIGATION

Morphine induces changes in the gut microbiome and metabolome in a morphine dependence model

(2018) Fuyuan Wang et al.   Scientific Reports

Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling

(2018) Enrique J. Cobos et al.   Cell Reports

Effects of Intravenous Infusion With Sodium Butyrate on Colonic Microbiota, Intestinal Development- and Mucosal Immune-Related Gene Expression in Normal Growing Pigs

(2018) Xue Chen et al.   Frontiers in Microbiology

Differential metabolic effects of oral butyrate treatment in lean versus metabolic syndrome subjects

(2018) KEC Bouter et al.   Clinical and Translational Gastroenterology

Gut microbiota, short chain fatty acids, and obesity across the epidemiologic transition: the METS-Microbiome study protocol

(2018) Lara R. Dugas et al.   BMC PUBLIC HEALTH

Beneficial effect of butyrate‐producing Lachnospiraceae on stress‐induced visceral hypersensitivity in rats

(2018) Jindong Zhang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Fecal microbiota transplantation relieve painful diabetic neuropathy

(2018) Ting-ting Cai et al.   MEDICINE

The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice

(2018) Swetha E. Murthy et al.   Science Translational Medicine

Decreased microbial co-occurrence network stability and SCFA receptor level correlates with obesity in African-origin women

(2018) Lara R. Dugas et al.   Scientific Reports

Liver X Receptors Protect Dorsal Root Ganglia from Obesity-Induced Endoplasmic Reticulum Stress and Mechanical Allodynia

(2018) Chaitanya K. Gavini et al.   Cell Reports

Gut Microbiota, Short-Chain Fatty Acids, and Herbal Medicines

(2018) Wuwen Feng et al.   Frontiers in Pharmacology

Body mass index and distribution of body fat can influence sensory detection and pain sensitivity

(2017) O. A Tashani et al.   EUROPEAN JOURNAL OF PAIN

Sodium butyrate improved intestinal immune function associated with NF-κB and p38MAPK signalling pathways in young grass carp ( Ctenopharyngodon idella )

(2017) Li Tian et al.   FISH & SHELLFISH IMMUNOLOGY

Role of the Gut Microbiome in the Pathogenesis of Obesity and Obesity-Related Metabolic Dysfunction

(2017) Kristien E. Bouter et al.   GASTROENTEROLOGY

Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy

(2017) Nigel A. Calcutt et al.   JOURNAL OF CLINICAL INVESTIGATION

The Short-Chain Fatty Acid Sodium Butyrate Functions as a Regulator of the Skin Immune System

(2017) Agatha Schwarz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Drosophila nociceptive sensitization requires BMP signaling via the canonical SMAD pathway

(2017) TL Follansbee et al.   JOURNAL OF NEUROSCIENCE

Neurological consequences of obesity

(2017) Phillipe D O'Brien et al.   LANCET NEUROLOGY

Gut microbiota is critical for the induction of chemotherapy-induced pain

(2017) Shiqian Shen et al.   NATURE NEUROSCIENCE

Drugging the pain epigenome

(2017) Ellen Niederberger et al.   Nature Reviews Neurology

Erratum: Structural plasticity and reorganisation in chronic pain

(2017) Rohini Kuner et al.   NATURE REVIEWS NEUROSCIENCE

Butyrate promotes visceral hypersensitivity in an IBS-like model via enteric glial cell-derived nerve growth factor

(2017) X. Long et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The gut microbiota as a key regulator of visceral pain

(2017) Siobhain M. Oʼ Mahony et al.   PAIN

Gut Microbiota and the Gut-Brain Axis

(2017) Nicolien C. de Clercq et al.   PSYCHOSOMATIC MEDICINE

Nociceptor Sensory Neuron–Immune Interactions in Pain and Inflammation

(2017) Felipe A. Pinho-Ribeiro et al.   TRENDS IN IMMUNOLOGY

Oxytocin Modulates Nociception as an Agonist of Pain-Sensing TRPV1

(2017) Yelena Nersesyan et al.   Cell Reports

Insulin-Like Growth Factor Binding Protein 6 in Rheumatoid Arthritis: A Possible Novel Chemotactic Factor?

(2017) Alessia Alunno et al.   Frontiers in Immunology

Reduced GABAergic neuronal activity in zona incerta causes neuropathic pain in a rat sciatic nerve chronic constriction injury model

(2017) Hyeong Cheol Moon et al.   Journal of Pain Research

Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella

(2016) Fabian Rivera-Chávez et al.   Cell Host & Microbe

Transcriptional networks of murine diabetic peripheral neuropathy and nephropathy: common and distinct gene expression patterns

(2016) Junguk Hur et al.   DIABETOLOGIA

Emerging role of intestinal microbiota and microbial metabolites in metabolic control

(2016) Hilde Herrema et al.   DIABETOLOGIA

Cytokine-like 1 Chemoattracts Monocytes/Macrophages via CCR2

(2016) Xiaolin Wang et al.   JOURNAL OF IMMUNOLOGY

Pain regulation by non-neuronal cells and inflammation

(2016) R.-R. Ji et al.   SCIENCE

Correlations of Fecal Metabonomic and Microbiomic Changes Induced by High-fat Diet in the Pre-Obesity State

(2016) Hong Lin et al.   Scientific Reports

Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium

(2016) Qianpeng Zhang et al.   Scientific Reports

Microbial metabolite butyrate facilitates M2 macrophage polarization and function

(2016) Jian Ji et al.   Scientific Reports

Spinal RyR2 pathway regulated by the RNA-binding protein HuD induces pain hypersensitivity in antiretroviral neuropathy

(2015) M.D. Sanna et al.   EXPERIMENTAL NEUROLOGY

Gut Microbiota and Energy Expenditure in Health and Obesity

(2015) Guido J. Bakker et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia

(2015) M.K. Nøhr et al.   NEUROSCIENCE

Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain

(2015) Bora Inceoglu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure

(2015) Virginie Mansuy-Aubert et al.   eLife

Effects of dietary microencapsulated sodium butyrate on growth, intestinal mucosal morphology, immune response and adhesive bacteria in juvenile common carp (Cyprinus carpio) pre-fed with or without oxidised oil

(2014) Wenshu Liu et al.   BRITISH JOURNAL OF NUTRITION

Role of the Microbiome in Energy Regulation and Metabolism

(2014) Max Nieuwdorp et al.   GASTROENTEROLOGY

Functional ryanodine receptors in the membranes of neurohypophysial secretory granules

(2014) James M. McNally et al.   JOURNAL OF GENERAL PHYSIOLOGY

Phenotyping animal models of diabetic neuropathy: a consensus statement of the diabetic neuropathy study group of the EASD (Neurodiab)

(2014) G.J. Biessels et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

CXCR4 Chemokine Receptor Signaling Mediates Pain in Diabetic Neuropathy

(2014) Daniela Maria Menichella et al.   Molecular Pain

Wnt-Fzd Signaling Sensitizes Peripheral Sensory Neurons via Distinct Noncanonical Pathways

(2014) Manuela Simonetti et al.   NEURON

Metabolically healthy and unhealthy obese - the 2013 Stock Conference report

(2014) D. Samocha-Bonet et al.   Obesity Reviews

Peripheral pain is enhanced by insulin-like growth factor 1 through a G protein-mediated stimulation of T-type calcium channels

(2014) Y. Zhang et al.   Science Signaling

The Female Urinary Microbiome: a Comparison of Women with and without Urgency Urinary Incontinence

(2014) M. M. Pearce et al.   mBio

From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation

(2014) Paola Italiani et al.   Frontiers in Immunology

Microbial Modulation of Energy Availability in the Colon Regulates Intestinal Transit

(2013) Anita Wichmann et al.   Cell Host & Microbe

Imbalance between Neutrophil Elastase and its Inhibitor α1-Antitrypsin in Obesity Alters Insulin Sensitivity, Inflammation, and Energy Expenditure

(2013) Virginie Mansuy-Aubert et al.   Cell Metabolism

GPR41/FFAR3 and GPR43/FFAR2 as Cosensors for Short-Chain Fatty Acids in Enteroendocrine Cells vs FFAR3 in Enteric Neurons and FFAR2 in Enteric Leukocytes

(2013) Mark K. Nøhr et al.   ENDOCRINOLOGY

Promiscuous Activation of Transient Receptor Potential Vanilloid 1 (TRPV1) Channels by Negatively Charged Intracellular Lipids

(2013) Viktor Lukacs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Attenuation of neuropathic pain by sodium butyrate in an experimental model of chronic constriction injury in rats

(2013) Ankesh Kukkar et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

Reflex Principles of Immunological Homeostasis

(2012) Ulf Andersson et al.   Annual Review of Immunology

Transcriptional Profiling of Diabetic Neuropathy in the BKS db/db Mouse: A Model of Type 2 Diabetes

(2011) M. Pande et al.   DIABETES

Phenotypic Changes in Diabetic Neuropathy Induced by a High-Fat Diet in Diabetic C57Bl/6 Mice

(2011) B. L. Guilford et al.   Experimental Diabetes Research

Protection against oxaliplatin-induced mechanical hyperalgesia and intraepidermal nerve fiber loss by minocycline

(2011) J. Boyette-Davis et al.   EXPERIMENTAL NEUROLOGY

Chronic Inflammation in Obesity and the Metabolic Syndrome

(2010) Rosário Monteiro et al.   MEDIATORS OF INFLAMMATION

The anorexigenic effects of metformin involve increases in hypothalamic leptin receptor expression

(2010) Grégory Aubert et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Ryanodine Receptors Contribute to the Induction of Nociceptive Input-Evoked Long-Term Potentiation in the Rat Spinal Cord Slice

(2010) Long-Zhen Cheng et al.   Molecular Pain

Abnormal calcium homeostasis in peripheral neuropathies

(2009) Paul Fernyhough et al.   CELL CALCIUM

Elevated Triglycerides Correlate With Progression of Diabetic Neuropathy

(2009) T. D. Wiggin et al.   DIABETES

The effects of butyrate enemas on visceral perception in healthy volunteers

(2009) s. a. l. w. vanhoutvin et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Inorganic Polyphosphate Modulates TRPM8 Channels

(2009) Eleonora Zakharian et al.   PLoS One

Epidermal nerve fiber quantification in the assessment of diabetic neuropathy

(2008) Kristina K. Beiswenger et al.   ACTA HISTOCHEMICA

The Utah Early Neuropathy Scale: a sensitive clinical scale for early sensory predominant neuropathy

(2008) J. Robinson Singleton et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM