Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion

Adgrf5 contributes to patterning of the endothelial deep layer in retina

(2019) C. Niaudet et al.   ANGIOGENESIS

Adhesion G protein-coupled receptors: opportunities for drug discovery

(2019) Frederic Bassilana et al.   NATURE REVIEWS DRUG DISCOVERY

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease

(2018) Jihwan Park et al.   SCIENCE

Activation of Adhesion G Protein-coupled Receptors

(2017) Lilian M. Demberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular Adenosine Stimulates Vacuolar ATPase–Dependent Proton Secretion in Medullary Intercalated Cells

(2017) Maria A. Battistone et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4)

(2017) Shun Lu et al.   PLoS One

Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq

(2017) Lihe Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Collecting Duct Intercalated Cell Function and Regulation

(2015) A. Roy et al.   Clinical Journal of the American Society of Nephrology

Targeted Disruption of Ig-Hepta/Gpr116 Causes Emphysema-like Symptoms That Are Associated with Alveolar Macrophage Activation

(2015) Donna Maretta Ariestanti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium

(2015) Colin Niaudet et al.   PLoS One

Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist

(2015) Hannah M. Stoveken et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping the H+ (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation

(2015) Maria Merkulova et al.   Scientific Reports

Identification and Characterization of Novel Renal Sensory Receptors

(2014) Premraj Rajkumar et al.   PLoS One

Orphan G Protein–Coupled Receptor GPR116 Regulates Pulmonary Surfactant Pool Size

(2013) James P. Bridges et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

GPR116, an Adhesion G-Protein-Coupled Receptor, Promotes Breast Cancer Metastasis via the G q-p63RhoGEF-Rho GTPase Pathway

(2013) X. Tang et al.   CANCER RESEARCH

Regulation of Luminal Acidification by the V-ATPase

(2013) Sylvie Breton et al.   PHYSIOLOGY

Lung Surfactant Levels are Regulated by Ig-Hepta/GPR116 by Monitoring Surfactant Protein D

(2013) Taku Fukuzawa et al.   PLoS One

Essential Regulation of Lung Surfactant Homeostasis by the Orphan G Protein-Coupled Receptor GPR116

(2013) Mi Young Yang et al.   Cell Reports

A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

(2012) Demet Araç et al.   EMBO JOURNAL

Regulation of V-ATPase recycling via a RhoA- and ROCKII-dependent pathway in epididymal clear cells

(2011) Winnie Waichi Shum et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Aldosterone stimulates vacuolar H+-ATPase activity in renal acid-secretory intercalated cells mainly via a protein kinase C-dependent pathway

(2011) Christian Winter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Induction of Metabolic Acidosis with Ammonium Chloride (NH4Cl) in Mice and Rats – Species Differences and Technical Considerations

(2011) Marta Nowik et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Angiotensin II Stimulates H+-ATPase Activity in Intercalated Cells from Isolated Mouse Connecting Tubules and Cortical Collecting Ducts

(2011) Carsten A. Wagner et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

PKA Regulates Vacuolar H+-ATPase Localization and Activity via Direct Phosphorylation of the A Subunit in Kidney Cells

(2010) Rodrigo Alzamora et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vacuolar ATPase Regulates Surfactant Secretion in Rat Alveolar Type II Cells by Modulating Lamellar Body Calcium

(2010) Narendranath Reddy Chintagari et al.   PLoS One

Regulation of the V-ATPase in kidney epithelial cells: dual role in acid-base homeostasis and vesicle trafficking

(2009) D. Brown et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Angiotensin II Activates H+-ATPase in Type A Intercalated Cells

(2008) V. Pech et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY