Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4)

Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system

(2017) H. Kaur et al.   Nature Communications

Targeted Ablation of Periostin-Expressing Activated Fibroblasts Prevents Adverse Cardiac Remodeling in MiceNovelty and Significance

(2016) Harmandeep Kaur et al.   CIRCULATION RESEARCH

Pharyngeal arch artery defects and lethal malformations of the aortic arch and its branches in mice deficient for the Hrt1/Hey1 transcription factor

(2016) Masahide Fujita et al.   MECHANISMS OF DEVELOPMENT

Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium

(2015) Colin Niaudet et al.   PLoS One

Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist

(2015) Hannah M. Stoveken et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Morphogenesis and molecular considerations on congenital cardiac septal defects

(2014) Adriana C. Gittenberger-de Groot et al.   ANNALS OF MEDICINE

A review of ELTD1, a pro-angiogenic adhesion GPCR

(2014) David M. Favara et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mesodermal expression of integrin α5β1 regulates neural crest development and cardiovascular morphogenesis

(2014) Dong Liang et al.   DEVELOPMENTAL BIOLOGY

Genetics of Atypical Hemolytic Uremic Syndrome (aHUS)

(2014) Marta Hidalgo et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-Coupled Receptors GPR126 and GPR133

(2014) Ines Liebscher et al.   Cell Reports

Orphan G Protein–Coupled Receptor GPR116 Regulates Pulmonary Surfactant Pool Size

(2013) James P. Bridges et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A Core Human Primary Tumor Angiogenesis Signature Identifies the Endothelial Orphan Receptor ELTD1 as a Key Regulator of Angiogenesis

(2013) Massimo Masiero et al.   CANCER CELL

Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome

(2013) Mathieu Lemaire et al.   NATURE GENETICS

Lung Surfactant Levels are Regulated by Ig-Hepta/GPR116 by Monitoring Surfactant Protein D

(2013) Taku Fukuzawa et al.   PLoS One

Sticky Signaling--Adhesion Class G Protein-Coupled Receptors Take the Stage

(2013) T. Langenhan et al.   Science Signaling

Embryology of the heart and its impact on understanding fetal and neonatal heart disease

(2013) Adriana C. Gittenberger-de Groot et al.   Seminars in Fetal & Neonatal Medicine

Atypical Hemolytic Uremic Syndrome

(2013) David Kavanagh et al.   SEMINARS IN NEPHROLOGY

Essential Regulation of Lung Surfactant Homeostasis by the Orphan G Protein-Coupled Receptor GPR116

(2013) Mi Young Yang et al.   Cell Reports

Genome-wide identification of endothelial cell-enriched genes in the mouse embryo

(2012) H. Takase et al.   BLOOD

The neural crest in cardiac congenital anomalies

(2012) Anna Keyte et al.   DIFFERENTIATION

A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

(2012) Demet Araç et al.   EMBO JOURNAL

Adipose tissue deletion ofGpr116impairs insulin sensitivity through modulation of adipose function

(2012) Tao Nie et al.   FEBS LETTERS

Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization

(2012) Lothar C Dieterich et al.   JOURNAL OF PATHOLOGY

STEC-HUS, atypical HUS and TTP are all diseases of complement activation

(2012) Marina Noris et al.   Nature Reviews Nephrology

Thrombotic microangiopathy and associated renal disorders

(2012) T. Barbour et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Augmented Cardiac Hypertrophy in Response to Pressure Overload in Mice Lacking ELTD1

(2012) Jinfeng Xiao et al.   PLoS One

Cardiovascular defects in a mouse model of HOXA1 syndrome

(2011) N. Makki et al.   HUMAN MOLECULAR GENETICS

The N Terminus of the Adhesion G Protein-coupled Receptor GPR56 Controls Receptor Signaling Activity

(2011) Kevin J. Paavola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endothelial  5 and  v integrins cooperate in remodeling of the vasculature during development

(2010) A. van der Flier et al.   DEVELOPMENT

Hepatic glycosphingolipid deficiency and liver function in mice

(2010) Richard Jennemann et al.   HEPATOLOGY

Tissue–Tissue Interactions During Morphogenesis of the Outflow Tract

(2009) Stacey Rentschler et al.   PEDIATRIC CARDIOLOGY

Identification of a Core Set of 58 Gene Transcripts With Broad and Specific Expression in the Microvasculature

(2008) Elisabet Wallgard et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY