Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling

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Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity

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CBASS Immunity Uses CARF-Related Effectors to Sense 3′–5′- and 2′–5′-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection

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Inflammatory Bowel Diseases: It's Time for the Adenosine System

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cGAS facilitates sensing of extracellular cyclic dinucleotides to activate innate immunity

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SLC19A1 Is an Importer of the Immunotransmitter cGAMP

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Cyclic GMP–AMP signalling protects bacteria against viral infection

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SLC19A1 transports immunoreactive cyclic dinucleotides

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Asymmetric distribution of TLR3 leads to a polarized immune response in human intestinal epithelial cells

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The Hypoxia–Adenosine Link during Intestinal Inflammation

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Direct activation of a phospholipase by cyclic GMP-AMP in El TorVibrio cholerae

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Neutrophils as sources of dinucleotide polyphosphates and metabolism by epithelial ENPP1 to influence barrier function via adenosine signaling

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Targeting STING with covalent small-molecule inhibitors

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Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response

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Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State

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c-di-AMP modulatesListeria monocytogenescentral metabolism to regulate growth, antibiotic resistance and osmoregulation

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Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing

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Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis

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Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

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Innate Immune Sensing and Signaling of Cytosolic Nucleic Acids

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Adenosine and inflammation: what's new on the horizon?

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Human Monocyte Recognition of Adenosine-Based Cyclic Dinucleotides Unveils the A2a GαsProtein-Coupled Receptor Tonic Inhibition of Mitochondrially Induced Cell Death

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Hydrolysis of 2′3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs

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Cyclic Dinucleotides and the Innate Immune Response

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Adenosine and gastrointestinal inflammation

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Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING

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The role of pattern recognition receptors in intestinal inflammation

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cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

(2013) Andrea Ablasser et al.   NATURE

Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP

(2013) Andrea Ablasser et al.   NATURE

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

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Adenosine and Hypoxia-Inducible Factor Signaling in Intestinal Injury and Recovery

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Di-Adenosine Tetraphosphate (Ap4A) Metabolism Impacts Biofilm Formation by Pseudomonas fluorescens via Modulation of c-di-GMP-Dependent Pathways

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c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response

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Epac1 mediates protein kinase A–independent mechanism of forskolin-activated intestinal chloride secretion

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A2B adenosine receptors in immunity and inflammation

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A2B Adenosine Receptor Gene Deletion Attenuates Murine Colitis

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Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

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