Metabolic precision labeling enables selective probing of O-linkedN-acetylgalactosamine glycosylation

Clickable Galactose Analogues for Imaging Glycans in Developing Zebrafish

(2020) Jessica L. Daughtry et al.   ACS Chemical Biology

A Sweet Galactose Transfer: Metabolic Oligosaccharide Engineering as a Tool To Study Glycans in Plasmodium Infection

(2020) Annabel Kitowski et al.   CHEMBIOCHEM

Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells

(2020) Benjamin Schumann et al.   MOLECULAR CELL

An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins

(2020) D. Judy Shon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SH3BP4 Regulates Intestinal Stem Cells and Tumorigenesis by Modulating β-Catenin Nuclear Localization

(2019) Pedro Antas et al.   Cell Reports

The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins

(2019) Stacy A. Malaker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of carbohydrate transfer activity of UDP-GalNAc: Polypeptide N-acetylgalactosaminyltransferase 7

(2019) Chang Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Quantitative Super-Resolution Microscopy of the Mammalian Glycocalyx

(2019) Leonhard Möckl et al.   DEVELOPMENTAL CELL

Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy

(2019) Heng-Huan Lee et al.   CANCER CELL

Polypeptide GalNAc-Ts: from redundancy to specificity

(2019) Matilde de las Rivas et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs

(2019) Junwon Choi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

VAMP8-mediated MUC2 mucin exocytosis from colonic goblet cells maintains innate intestinal homeostasis

(2019) Steve Cornick et al.   Nature Communications

NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor

(2019) Laura Novellasdemunt et al.   EMBO JOURNAL

Deciphering Protein O-Glycosylation: Solid-Phase Chemoenzymatic Cleavage and Enrichment

(2018) Shuang Yang et al.   ANALYTICAL CHEMISTRY

Artificial Cysteine S-Glycosylation Induced by Per-O-Acetylated Unnatural Monosaccharides during Metabolic Glycan Labeling

(2018) Wei Qin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

O-linked mucin-type glycosylation in breast cancer

(2018) Joy M. Burchell et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1

(2018) Chia-Wei Li et al.   CANCER CELL

Mapping and Quantification of Over 2000 O-linked Glycopeptides in Activated Human T Cells with Isotope-Targeted Glycoproteomics (Isotag)

(2018) Christina M. Woo et al.   MOLECULAR & CELLULAR PROTEOMICS

Intestinal organoids for modelling intestinal development and disease

(2018) Kathryn L. Fair et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Monolayer culture of intestinal epithelium sustains Lgr5+ intestinal stem cells

(2018) Yuan Liu et al.   Cell Discovery

Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines

(2018) John Hintze et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Whole Proteome Profiling of N-Myristoyltransferase Activity and Inhibition Using Sortase A

(2018) Andrea Goya Grocin et al.   MOLECULAR & CELLULAR PROTEOMICS

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

The small molecule luteolin inhibitsN-acetyl-α-galactosaminyltransferases and reduces mucin-typeO-glycosylation of amyloid precursor protein

(2017) Feng Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8

(2017) Kelly N. Chuh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides

(2017) Minyong Chen et al.   Nature Communications

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens

(2017) David W. Morgens et al.   Nature Communications

Catalytic Promiscuity of O-GlcNAc Transferase Enables Unexpected Metabolic Engineering of Cytoplasmic Proteins with 2-Azido-2-deoxy-glucose

(2016) David L. Shen et al.   ACS Chemical Biology

An OGA-Resistant Probe Allows Specific Visualization and Accurate Identification of O-GlcNAc-Modified Proteins in Cells

(2016) Jing Li et al.   ACS Chemical Biology

Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes

(2016) David W Morgens et al.   NATURE BIOTECHNOLOGY

Isotope-targeted glycoproteomics (IsoTaG): a mass-independent platform for intact N- and O-glycopeptide discovery and analysis

(2015) Christina M Woo et al.   NATURE METHODS

Efficient genetic engineering of human intestinal organoids using electroporation

(2015) Masayuki Fujii et al.   Nature Protocols

Expanding the scope of cyclopropene reporters for the detection of metabolically engineered glycoproteins by Diels–Alder reactions

(2014) Anne-Katrin Späte et al.   Beilstein Journal of Organic Chemistry

Carbohydrate Sequence of the Prostate Cancer-associated Antigen F77 Assigned by a MucinO-Glycome Designer Array

(2014) Chao Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immature truncated O-glycophenotype of cancer directly induces oncogenic features

(2014) Prakash Radhakrishnan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Labeling of Metabolically Engineered Cell-Surface Glycoconjugates with a Carbamate-Linked Cyclopropene Reporter

(2013) Anne-Katrin Späte et al.   BIOCONJUGATE CHEMISTRY

Evaluation of Analogues of GalNAc as Substrates for Enzymes of the Mammalian GalNAc Salvage Pathway

(2012) Sabrina Pouilly et al.   ACS Chemical Biology

Live-Cell Imaging of Cyclopropene Tags with Fluorogenic Tetrazine Cycloadditions

(2012) Jun Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation

(2012) Leslie A. Bateman et al.   CHEMICAL COMMUNICATIONS

Functionalized Cyclopropenes As Bioorthogonal Chemical Reporters

(2012) David M. Patterson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners

(2012) S.-H. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study

(2011) Christen Besanceney-Webler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In vivo and in vitro function of human UDP-galactose 4′-epimerase variants

(2011) Thomas J. McCorvie et al.   BIOCHIMIE

Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1

(2011) B. W. Zaro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic cross-talk allows labeling of O-linked  -N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway

(2011) M. Boyce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UDP-galactose 4' epimerase (GALE) is essential for development of Drosophila melanogaster

(2010) R. D. Sanders et al.   Disease Models & Mechanisms

Simultaneous determination of nucleotide sugars with ion-pair reversed-phase HPLC

(2010) Kazuki Nakajima et al.   GLYCOBIOLOGY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Lectins as tools in glycoconjugate research

(2008) Albert M. Wu et al.   GLYCOCONJUGATE JOURNAL