Mapping and Quantification of Over 2000 O-linked Glycopeptides in Activated Human T Cells with Isotope-Targeted Glycoproteomics (Isotag)

Hyper-O-GlcNAcylation activates nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) signaling through interplay with phosphorylation and acetylation

(2017) Zhiyuan Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development of IsoTaG, a Chemical Glycoproteomics Technique for Profiling Intact N- and O-Glycopeptides from Whole Cell Proteomes

(2017) Christina M. Woo et al.   JOURNAL OF PROTEOME RESEARCH

A mutant O-GlcNAcase enriches Drosophila developmental regulators

(2017) Nithya Selvan et al.   Nature Chemical Biology

Elucidating crosstalk mechanisms between phosphorylation and O-GlcNAcylation

(2017) Aneika C. Leney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High Glucose Stimulates Tumorigenesis in Hepatocellular Carcinoma Cells Through AGER-Dependent O-GlcNAcylation of c-Jun

(2016) Yongxia Qiao et al.   DIABETES

Global Analysis ofO-GlcNAc Glycoproteins in Activated Human T Cells

(2016) Peder J. Lund et al.   JOURNAL OF IMMUNOLOGY

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

(2016) Mahima Swamy et al.   NATURE IMMUNOLOGY

The nutrient sensor OGT in PVN neurons regulates feeding

(2016) O. Lagerlof et al.   SCIENCE

O-GlcNAc occurs cotranslationally to stabilize nascent polypeptide chains

(2015) Yanping Zhu et al.   Nature Chemical Biology

O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease

(2015) Nicholas P. Marotta et al.   Nature Chemistry

Isotope-targeted glycoproteomics (IsoTaG): a mass-independent platform for intact N- and O-glycopeptide discovery and analysis

(2015) Christina M Woo et al.   NATURE METHODS

The active site of O-GlcNAc transferase imposes constraints on substrate sequence

(2015) Shalini Pathak et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Post-translationalO-GlcNAcylation is essential for nuclear pore integrity and maintenance of the pore selectivity filter

(2015) Yanping Zhu et al.   Journal of Molecular Cell Biology

The active site of O-GlcNAc transferase imposes constraints on substrate sequence

(2015) Shalini Pathak et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Novel LC-MS2 Product Dependent Parallel Data Acquisition Function and Data Analysis Workflow for Sequencing and Identification of Intact Glycopeptides

(2014) Sz-Wei Wu et al.   ANALYTICAL CHEMISTRY

O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells

(2013) H. M. Itkonen et al.   CANCER RESEARCH

Emerging roles for protein S-palmitoylation in immunity from chemical proteomics

(2013) Jacob S Yount et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Human T Cell Activation Results in Extracellular Signal-regulated Kinase (ERK)-Calcineurin-dependent Exposure of Tn Antigen on the Cell Surface and Binding of the Macrophage Galactose-type Lectin (MGL)

(2013) Sandra J. van Vliet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-GlcNAcylation of Cofilin Promotes Breast Cancer Cell Invasion

(2013) Xun Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteome Wide Purification and Identification of O-GlcNAc-Modified Proteins Using Click Chemistry and Mass Spectrometry

(2013) Hannes Hahne et al.   JOURNAL OF PROTEOME RESEARCH

O-GlcNAcase is essential for embryonic development and maintenance of genomic stability

(2012) Yong Ryoul Yang et al.   AGING CELL

Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes

(2012) Aksana A Labokha et al.   EMBO JOURNAL

Global Identification and Characterization of BothO-GlcNAcylation and Phosphorylation at the Murine Synapse

(2012) Jonathan C. Trinidad et al.   MOLECULAR & CELLULAR PROTEOMICS

Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis

(2012) Mary Katherine Tarrant et al.   Nature Chemical Biology

Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism

(2012) W. Yi et al.   SCIENCE

Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

(2011) Gerald W. Hart et al.   Annual Review of Biochemistry

Sulfated Ligands for the Copper(I)-Catalyzed Azide-Alkyne Cycloaddition

(2011) Wei Wang et al.   Chemistry-An Asian Journal

Combining High-Energy C-Trap Dissociation and Electron Transfer Dissociation for Protein O-GlcNAc Modification Site Assignment

(2011) Peng Zhao et al.   JOURNAL OF PROTEOME RESEARCH

Structure of human O-GlcNAc transferase and its complex with a peptide substrate

(2011) Michael B. Lazarus et al.   NATURE

Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1

(2011) B. W. Zaro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic cross-talk allows labeling of O-linked  -N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway

(2011) M. Boyce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

O-Linked-N-acetylglucosamine on extracellular protein domains mediates epithelial cell–matrix interactions

(2011) Yuta Sakaidani et al.   Nature Communications

Quantification of O-glycosylation stoichiometry and dynamics using resolvable mass tags

(2010) Jessica E Rexach et al.   Nature Chemical Biology

O-linked β-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress

(2009) Chutikarn Butkinaree et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease

(2009) F. Liu et al.   BRAIN

Genome-wide Analysis of Histone Methylation Reveals Chromatin State-Based Regulation of Gene Transcription and Function of Memory CD8+ T Cells

(2009) Yasuto Araki et al.   IMMUNITY

Regulation of Calcium/Calmodulin-dependent Kinase IV byO-GlcNAc Modification

(2009) Wagner B. Dias et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways

(2009) Q. Zeidan et al.   JOURNAL OF CELL SCIENCE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Quantitative Phosphoproteomic Analysis of T Cell Receptor Signaling Reveals System-Wide Modulation of Protein-Protein Interactions

(2009) V. Mayya et al.   Science Signaling

Direct In-Gel Fluorescence Detection and Cellular Imaging ofO-GlcNAc-Modified Proteins

(2008) Peter M. Clark et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

(2008) Xiaoyong Yang et al.   NATURE

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH