Allium roseum L. extract inhibits amyloid beta aggregation and toxicity involved in Alzheimer’s disease

Dietary supplementation with Allium hirtifolium and/or Astragalus hamosus improved memory and reduced neuro-inflammation in the rat model of Alzheimer’s disease

(2018) Zahra Bahaeddin et al.   Applied Physiology Nutrition and Metabolism

Oleuropein aglycone: A polyphenol with different targets against amyloid toxicity

(2018) Manuela Leri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Protective effect of kaempferol on the transgenic Drosophila model of Alzheimer’s disease

(2018) Yasir Hasan Siddique et al.   CNS & Neurological Disorders-Drug Targets

Screening for amyloid-β aggregation inhibitor and neuronal toxicity of eight Tunisian medicinal plants

(2018) Zohra Dhouafli et al.   INDUSTRIAL CROPS AND PRODUCTS

Amyloid β-42 induces neuronal apoptosis by targeting mitochondria

(2017) Xiao-Jian Han et al.   Molecular Medicine Reports

Phytochemical analysis, antimicrobial and antioxidant activities of Allium roseum var. odoratissimum (Desf.) Coss extracts

(2016) Mejdi Snoussi et al.   INDUSTRIAL CROPS AND PRODUCTS

The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies

(2016) Manuela Leri et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

(2016) Rafael C. Dutra et al.   PHARMACOLOGICAL RESEARCH

The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy

(2016) Urmi Sengupta et al.   EBioMedicine

Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases

(2016) Elisa Evangelisti et al.   Scientific Reports

Membrane Interactions of Phytochemicals as Their Molecular Mechanism Applicable to the Discovery of Drug Leads from Plants

(2015) Hironori Tsuchiya   MOLECULES

Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates

(2015) Ilaria Luccarini et al.   NEUROBIOLOGY OF AGING

Beneficial properties of natural phenols: Highlight on protection against pathological conditions associated with amyloid aggregation

(2014) Massimo Stefani et al.   BIOFACTORS

Naturally occurring polyphenolic inhibitors of amyloid beta aggregation

(2014) Quentin I. Churches et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Soluble Aβ Oligomers Are Rapidly Sequestered from Brain ISF In Vivo and Bind GM1 Ganglioside on Cellular Membranes

(2014) Soyon Hong et al.   NEURON

Partitioning and confinement of GM1 ganglioside induced by amyloid aggregates

(2013) Martino Calamai et al.   FEBS LETTERS

Cytotoxicity of Intracellular A 42 Amyloid Oligomers Involves Ca2+ Release from the Endoplasmic Reticulum by Stimulated Production of Inositol Trisphosphate

(2013) A. Demuro et al.   JOURNAL OF NEUROSCIENCE

The Polyphenol Oleuropein Aglycone Protects TgCRND8 Mice against Aß Plaque Pathology

(2013) Cristina Grossi et al.   PLoS One

Presenilins and  -Secretase: Structure, Function, and Role in Alzheimer Disease

(2013) B. De Strooper et al.   Cold Spring Harbor Perspectives in Medicine

Trafficking and Proteolytic Processing of APP

(2013) C. Haass et al.   Cold Spring Harbor Perspectives in Medicine

Inhibition of β-amyloid peptide-induced neurotoxicity by kaempferol 3-O-(6″-acetyl)-β-glucopyranoside from butterbur (Petasites japonicus) leaves in B103 cells

(2012) Kyung-Sik Song et al.   FOOD SCIENCE AND BIOTECHNOLOGY

Potential benefits of adherence to the Mediterranean diet on cognitive health

(2012) Catherine Féart et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Phenolic constituents, antioxidant and antimicrobial activities of rosy garlic (Allium roseum var. odoratissimum)

(2012) Selma Dziri et al.   Journal of Functional Foods

Enhanced ROS Generation Mediated by Alzheimer's Disease Presenilin Regulation of InsP3R Ca2+ Signaling

(2010) Marioly Müller et al.   ANTIOXIDANTS & REDOX SIGNALING

Antioxidant and Antimicrobial Activities of Allium roseum L. “Lazoul,” A Wild Edible Endemic Species in North Africa

(2010) Hanen Najjaa et al.   INTERNATIONAL JOURNAL OF FOOD PROPERTIES

Aromatic Small Molecules Remodel Toxic Soluble Oligomers of Amyloid β through Three Independent Pathways

(2010) Ali Reza A. Ladiwala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural requirements for the flavonoid fisetin in inhibiting fibril formation of amyloid β protein

(2008) Tatsuhiro Akaishi et al.   NEUROSCIENCE LETTERS

Garlic extract exhibits antiamyloidogenic activity on amyloid-beta fibrillogenesis: relevance to Alzheimer's disease

(2008) Veer Bala Gupta et al.   PHYTOTHERAPY RESEARCH