Enhanced ROS Generation Mediated by Alzheimer's Disease Presenilin Regulation of InsP3R Ca2+ Signaling

Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

(2010) César Cárdenas et al.   CELL

Gain-of-Function Enhancement of IP3 Receptor Modal Gating by Familial Alzheimer's Disease-Linked Presenilin Mutants in Human Cells and Mouse Neurons

(2010) K.-H. Cheung et al.   Science Signaling

The role of Ca2+ signaling in the coordination of mitochondrial ATP production with cardiac work

(2009) Robert S. Balaban   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Crosstalk signaling between mitochondrial Ca2+ and ROS

(2009) Robert et al.   Frontiers in Bioscience-Landmark

Deviant Ryanodine Receptor-Mediated Calcium Release Resets Synaptic Homeostasis in Presymptomatic 3xTg-AD Mice

(2009) S. Chakroborty et al.   JOURNAL OF NEUROSCIENCE

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

(2009) K. V. Kuchibhotla et al.   SCIENCE

Toward Structural Elucidation of the γ-Secretase Complex

(2009) Huilin Li et al.   STRUCTURE

High- and low-calcium-dependent mechanisms of mitochondrial calcium signalling

(2008) A SPAT et al.   CELL CALCIUM

SERCA pump activity is physiologically regulated by presenilin and regulates amyloid β production

(2008) Kim N. Green et al.   JOURNAL OF GENERAL PHYSIOLOGY

Mechanism of Ca2+ Disruption in Alzheimer's Disease by Presenilin Regulation of InsP3 Receptor Channel Gating

(2008) King-Ho Cheung et al.   NEURON

Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks

(2008) Kishore V. Kuchibhotla et al.   NEURON

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease

(2008) M. A. Busche et al.   SCIENCE

Increased Vulnerability of Hippocampal Neurons from Presenilin-1 Mutant Knock-In Mice to Amyloid β-Peptide Tox

(2003) Qing Guo et al.   JOURNAL OF NEUROCHEMISTRY