Structures of translationally inactive mammalian ribosomes

Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

(2018) Rajiv K. Khajuria et al.   CELL

Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance

(2018) Simone Pellegrino et al.   JOURNAL OF MOLECULAR BIOLOGY

Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells

(2018) Jeremy D. Grevet et al.   SCIENCE

MonoRes: Automatic and Accurate Estimation of Local Resolution for Electron Microscopy Maps

(2018) Jose Luis Vilas et al.   STRUCTURE

Alternative Mode of E-Site tRNA Binding in the Presence of a Downstream mRNA Stem Loop at the Entrance Channel

(2018) Yan Zhang et al.   STRUCTURE

Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide

(2017) Zhen Shi et al.   MOLECULAR CELL

Visualization of chemical modifications in the human 80S ribosome structure

(2017) S. Kundhavai Natchiar et al.   NATURE

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

UBE2O remodels the proteome during terminal erythroid differentiation

(2017) Anthony T. Nguyen et al.   SCIENCE

Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes

(2016) Sichen Shao et al.   CELL

Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy

(2016) J.M. de la Rosa-Trevín et al.   JOURNAL OF STRUCTURAL BIOLOGY

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Dynamic Regulation of a Ribosome Rescue Pathway in Erythroid Cells and Platelets

(2016) Eric W. Mills et al.   Cell Reports

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

(2016) Dari Kimanius et al.   eLife

Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation

(2016) Ryuta Ishimura et al.   eLife

Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations

(2015) V. Ljungstrom et al.   BLOOD

Molecular architecture of the ribosome-bound Hepatitis C Virus internal ribosomal entry site RNA

(2015) H. Yamamoto et al.   EMBO JOURNAL

Semi-automated selection of cryo-EM particles in RELION-1.3

(2015) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Structural basis for stop codon recognition in eukaryotes

(2015) Alan Brown et al.   NATURE

Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry

(2015) Fan Liu et al.   NATURE METHODS

EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy

(2015) Benjamin A Barad et al.   NATURE METHODS

Cryo-EM structure of Hepatitis C virus IRES bound to the human ribosome at 3.9-Å resolution

(2015) Nick Quade et al.   Nature Communications

Translation of 5′ leaders is pervasive in genes resistant to eIF2 repression

(2015) Dmitry E Andreev et al.   eLife

Sampling the conformational space of the catalytic subunit of human γ-secretase

(2015) Xiao-chen Bai et al.   eLife

Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions

(2015) Alan Brown et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Initiation of Translation by Cricket Paralysis Virus IRES Requires Its Translocation in the Ribosome

(2014) Israel S. Fernández et al.   CELL

Structure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å Resolution

(2014) Rebecca M. Voorhees et al.   CELL

Cellular Differences in Protein Synthesis Regulate Tissue Homeostasis

(2014) Michael Buszczak et al.   CELL

Translational control by heme-regulated eIF2α kinase during erythropoiesis

(2014) Jane-Jane Chen   CURRENT OPINION IN HEMATOLOGY

Dom34-Hbs1 mediated dissociation of inactive 80S ribosomes promotes restart of translation after stress

(2014) Antonia M G van den Elzen et al.   EMBO JOURNAL

Structure of the Yeast Mitochondrial Large Ribosomal Subunit

(2014) A. Amunts et al.   SCIENCE

Structures of the human and Drosophila 80S ribosome

(2013) Andreas M. Anger et al.   NATURE

Erythropoiesis: Development and Differentiation

(2013) E. Dzierzak et al.   Cold Spring Harbor Perspectives in Medicine

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

The Saccharomyces cerevisiae protein Stm1p facilitates ribosome preservation during quiescence

(2012) Natalya Van Dyke et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Overexpression of Eukaryotic Translation Elongation Factor 3 Impairs Gcn2 Protein Activation

(2012) Jyothsna Visweswaraiah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia

(2012) Kim De Keersmaecker et al.   NATURE GENETICS

Stm1 modulates translation after 80S formation in Saccharomyces cerevisiae

(2011) V. Balagopal et al.   RNA

The Structure of the Eukaryotic Ribosome at 3.0 A Resolution

(2011) A. Ben-Shem et al.   SCIENCE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Ribosomopathies: human disorders of ribosome dysfunction

(2010) A. Narla et al.   BLOOD

Stress-sensitive Regulation of IFRD1 mRNA Decay Is Mediated by an Upstream Open Reading Frame

(2010) Chenyang Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Driving ribosome assembly

(2009) Dieter Kressler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs

(2009) D. M. Landry et al.   GENES & DEVELOPMENT

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

(2008) Benjamin L. Ebert et al.   NATURE