Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria

Melatonin receptor ligands: A pharmaco‐chemical perspective

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Cellular absorption of small molecules: free energy landscapes of melatonin binding at phospholipid membranes

(2020) Huixia Lu et al.   Scientific Reports

OPLS3e: Extending Force Field Coverage for Drug-Like Small Molecules

(2019) Katarina Roos et al.   Journal of Chemical Theory and Computation

Total Synthesis of (-)-Clavicipitic Acid via γ,γ-Dimethylallyltryptophan (DMAT) and Chemoselective C−H Hydroxylation

(2019) Francesca Bartoccini et al.   JOURNAL OF ORGANIC CHEMISTRY

XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity

(2019) Linda C. Johansson et al.   NATURE

Structural basis of ligand recognition at the human MT1 melatonin receptor

(2019) Benjamin Stauch et al.   NATURE

Binding and dynamics of melatonin at the interface of phosphatidylcholine-cholesterol membranes

(2019) Huixia Lu et al.   PLoS One

Total Synthesis of Isodaphlongamine H: A Possible Biogenetic Conundrum

(2016) Amit Kumar Chattopadhyay et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

MT1and MT2Melatonin Receptors: A Therapeutic Perspective

(2016) Jiabei Liu et al.   Annual Review of Pharmacology and Toxicology

Update on melatonin receptors: IUPHAR Review 20

(2016) Ralf Jockers et al.   BRITISH JOURNAL OF PHARMACOLOGY

Catalytic Enantioselective Synthesis of N,Cα,Cα-Trisubstituted α-Amino Acid Derivatives Using 1H-Imidazol-4(5H)-ones as Key Templates

(2015) Julen Etxabe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Selective melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways

(2015) Martha Lopez-Canul et al.   PAIN

UniPR129 is a competitive small molecule Eph-ephrin antagonist blockingin vitroangiogenesis at low micromolar concentrations

(2014) I Hassan-Mohamed et al.   BRITISH JOURNAL OF PHARMACOLOGY

Synthesis, chiral resolution, absolute configuration assignment and pharmacological evaluation of a series of melatoninergic ligands

(2014) Mohamed Ettaoussi et al.   MedChemComm

Synthesis and Pharmacological Evaluation of a series of the Agomelatine Analogues as Melatonin MT1/MT2Agonist and 5-HT2CAntagonist

(2013) Mohamed Ettaoussi et al.   ChemMedChem

MT1 and MT2 Melatonin Receptors: Ligands, Models, Oligomers, and Therapeutic Potential

(2013) Darius. P. Zlotos et al.   JOURNAL OF MEDICINAL CHEMISTRY

Toward the Definition of Stereochemical Requirements for MT2-Selective Antagonists and Partial Agonists by Studying 4-Phenyl-2-propionamidotetralin Derivatives

(2011) Annalida Bedini et al.   JOURNAL OF MEDICINAL CHEMISTRY

Promotion of Non-Rapid Eye Movement Sleep and Activation of Reticular Thalamic Neurons by a Novel MT2 Melatonin Receptor Ligand

(2011) R. Ochoa-Sanchez et al.   JOURNAL OF NEUROSCIENCE

OPM database and PPM web server: resources for positioning of proteins in membranes

(2011) Mikhail A. Lomize et al.   NUCLEIC ACIDS RESEARCH

Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors

(2010) Alessia Carocci et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and Characterization of in Vitro and in Vivo Profiles of Hydroxybupropion Analogues: Aids to Smoking Cessation

(2010) Ronald J. Lukas et al.   JOURNAL OF MEDICINAL CHEMISTRY

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Melatonin—A pleiotropic, orchestrating regulator molecule

(2010) Rüdiger Hardeland et al.   PROGRESS IN NEUROBIOLOGY

N-(Anilinoethyl)amides: Design and Synthesis of Metabolically Stable, Selective Melatonin Receptor Ligands

(2009) Silvia Rivara et al.   ChemMedChem