Activation of Macrophages by Lysophosphatidic Acid through the Lysophosphatidic Acid Receptor 1 as a Novel Mechanism in Multiple Sclerosis Pathogenesis

Lipopolysaccharide mediates time-dependent macrophage M1/M2 polarization through the Tim-3/Galectin-9 signalling pathway

(2019) Wang Zhang et al.   EXPERIMENTAL CELL RESEARCH

LPA Induces Metabolic Reprogramming in Ovarian Cancer via a Pseudohypoxic Response

(2018) Ji Hee Ha et al.   CANCER RESEARCH

Elevated lysophosphatidic acid levels in the serum and cerebrospinal fluid in patients with multiple sclerosis: therapeutic response and clinical implication

(2018) Dongxiao Jiang et al.   NEUROLOGICAL RESEARCH

A Combination of Ontogeny and CNS Environment Establishes Microglial Identity

(2018) F. Chris Bennett et al.   NEURON

Identifying lysophosphatidic acid receptor subtype 1 (LPA1) as a novel factor to modulate microglial activation and their TNF-α production by activating ERK1/2

(2018) Jin Hyun Kwon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lysophosphatidic acid and its receptor LPA1 mediate carrageenan induced inflammatory pain in mice

(2018) Malavika Srikanth et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Lysophosphatidic acid and amitriptyline signal through LPA1R to reduce P-glycoprotein transport at the blood–brain barrier

(2017) David B Banks et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The fate and lifespan of human monocyte subsets in steady state and systemic inflammation

(2017) Amit A. Patel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autotaxin-Lysophosphatidic Acid: From Inflammation to Cancer Development

(2017) Silvia Anahi Valdés-Rives et al.   MEDIATORS OF INFLAMMATION

Dysregulation of lysophosphatidic acids in multiple sclerosis and autoimmune encephalomyelitis

(2017) K. Schmitz et al.   Acta Neuropathologica Communications

1-Oleyl-lysophosphatidic acid (LPA) promotes polarization of BV-2 and primary murine microglia towards an M1-like phenotype

(2016) Ioanna Plastira et al.   Journal of Neuroinflammation

Anatomical location of LPA1activation and LPA phospholipid precursors in rodent and human brain

(2015) Estibaliz González de San Román et al.   JOURNAL OF NEUROCHEMISTRY

Lysophosphatidic Acid Signaling in the Nervous System

(2015) Yun C. Yung et al.   NEURON

Discordant Growth of Monozygotic Twins Starts at the Blastocyst Stage: A Case Study

(2015) Laila Noli et al.   Stem Cell Reports

Lysophosphatidic Acid Up-Regulates Hexokinase II and Glycolysis to Promote Proliferation of Ovarian Cancer Cells

(2015) Abir Mukherjee et al.   NEOPLASIA

Loss of lysophosphatidic acid receptor LPA1 alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex

(2014) Beatriz García-Díaz et al.   Brain Structure & Function

Elevated serum levels of lysophosphatidic acid in patients with multiple sclerosis

(2014) Mohammad Balood et al.   HUMAN IMMUNOLOGY

Role of Rho kinase in lysophosphatidic acid-induced altering of blood-brain barrier permeability

(2014) YING YU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

LPA receptor signaling: pharmacology, physiology, and pathophysiology

(2014) Yun C. Yung et al.   JOURNAL OF LIPID RESEARCH

Macrophages and CNS remyelination

(2014) Veronique E. Miron et al.   JOURNAL OF NEUROCHEMISTRY

Necessity of Lysophosphatidic Acid Receptor 1 for Development of Arthritis

(2013) Yoshishige Miyabe et al.   ARTHRITIS AND RHEUMATISM

Rapid and Reversible Enhancement of Blood–Brain Barrier Permeability Using Lysophosphatidic Acid

(2013) Ngoc H On et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

(2013) Daphne YS Vogel et al.   Journal of Neuroinflammation

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Lysophosphatidic acid in atherosclerotic diseases

(2012) Andreas Schober et al.   BRITISH JOURNAL OF PHARMACOLOGY

Atherosclerotic Lesion Progression Changes Lysophosphatidic Acid Homeostasis to Favor its Accumulation

(2010) Martine Bot et al.   AMERICAN JOURNAL OF PATHOLOGY

LPA Receptors: Subtypes and Biological Actions

(2010) Ji Woong Choi et al.   Annual Review of Pharmacology and Toxicology

Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture

(2009) Eva Bernhart et al.   PROTEOMICS

LPA modulates monocyte migration directly and via LPA-stimulated endothelial cells

(2008) Cindy Gustin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Lysophosphatidic acid upregulates vascular endothelial growth factor-C and tube formation in human endothelial cells through LPA1/3, COX-2, and NF-κB activation- and EGFR transactivation-dependent mechanisms

(2008) Chi-Iou Lin et al.   CELLULAR SIGNALLING