Subcellular Localization of MxB Determines Its Antiviral Potential against Influenza A Virus

Human antiviral protein MxA forms novel metastable membrane-less cytoplasmic condensates exhibiting rapid reversible tonicity-driven phase transitions

(2019) Deodate Davis et al.   JOURNAL OF VIROLOGY

Mechanisms of nuclear mRNA export: A structural perspective

(2019) Yihu Xie et al.   TRAFFIC

Influenza restriction factor MxA functions as inflammasome sensor in the respiratory epithelium

(2019) SangJoon Lee et al.   Science Immunology

Let me in: Control of HIV nuclear entry at the nuclear envelope

(2018) Anvita Bhargava et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Effects of allelic variations in the human myxovirus resistance protein A on its antiviral activity

(2018) Laura Graf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human MxB protein is a pan-herpesvirus restriction factor

(2018) Mirjam Schilling et al.   JOURNAL OF VIROLOGY

MXB inhibits murine cytomegalovirus

(2018) Ananda Ayyappann Jaguva Vasudevan et al.   VIROLOGY

MxB is an interferon-induced restriction factor of human herpesviruses

(2018) Michel Crameri et al.   Nature Communications

SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses

(2018) Dominik Dornfeld et al.   Scientific Reports

Human MX2/MxB: a potent interferon-induced post-entry inhibitor of herpesviruses and HIV-1

(2018) Peter Staeheli et al.   JOURNAL OF VIROLOGY

Human MxB Inhibits the Replication of Hepatitis C Virus

(2018) Dong-Rong Yi et al.   JOURNAL OF VIROLOGY

Role of Nucleotide Binding and GTPase Domain Dimerization in Dynamin-like Myxovirus Resistance Protein A for GTPase Activation and Antiviral Activity

(2015) Alexej Dick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oligomerization and GTP-binding Requirements of MxA for Viral Target Recognition and Antiviral Activity against Influenza A Virus

(2015) Patricia E. Nigg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal

(2015) Bianca Schulte et al.   JOURNAL OF VIROLOGY

Mx GTPases: dynamin-like antiviral machines of innate immunity

(2015) Otto Haller et al.   TRENDS IN MICROBIOLOGY

Structural Insight into HIV-1 Restriction by MxB

(2014) Jennifer L. Fribourgh et al.   Cell Host & Microbe

Structural Requirements for the Antiviral Activity of the Human MxA Protein against Thogoto and Influenza A Virus

(2014) Corinna Patzina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Host and Viral Determinants of Mx2 Antiretroviral Activity

(2014) Idoia Busnadiego et al.   JOURNAL OF VIROLOGY

Transfer of the Amino-Terminal Nuclear Envelope Targeting Domain of Human MX2 Converts MX1 into an HIV-1 Resistance Factor

(2014) C. Goujon et al.   JOURNAL OF VIROLOGY

Host and viral determinants for MxB restriction of HIV-1 infection

(2014) Kenneth A Matreyek et al.   Retrovirology

The Interferon-Inducible MxB Protein Inhibits HIV-1 Infection

(2013) Zhenlong Liu et al.   Cell Host & Microbe

The Human Interferon-Induced MxA Protein Inhibits Early Stages of Influenza A Virus Infection by Retaining the Incoming Viral Genome in the Cytoplasm

(2013) Han Xiao et al.   JOURNAL OF VIROLOGY

Mx Proteins: Antiviral Gatekeepers That Restrain the Uninvited

(2013) J. Verhelst et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

(2013) Caroline Goujon et al.   NATURE

MX2 is an interferon-induced inhibitor of HIV-1 infection

(2013) Melissa Kane et al.   NATURE

Pandemic Influenza A Viruses Escape from Restriction by Human MxA through Adaptive Mutations in the Nucleoprotein

(2013) Benjamin Mänz et al.   PLoS Pathogens

Evolution-Guided Identification of Antiviral Specificity Determinants in the Broadly Acting Interferon-Induced Innate Immunity Factor MxA

(2012) Patrick S. Mitchell et al.   Cell Host & Microbe

Interferon-Inducible Protein Mx1 Inhibits Influenza Virus by Interfering with Functional Viral Ribonucleoprotein Complex Assembly

(2012) J. Verhelst et al.   JOURNAL OF VIROLOGY

Structure of Myxovirus Resistance Protein A Reveals Intra- and Intermolecular Domain Interactions Required for the Antiviral Function

(2011) Song Gao et al.   IMMUNITY

Interferon-induced Antiviral Protein MxA Interacts with the Cellular RNA Helicases UAP56 and URH49

(2011) Christian Wisskirchen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Viral Nucleoprotein Determines Mx Sensitivity of Influenza A Viruses

(2011) P. Zimmermann et al.   JOURNAL OF VIROLOGY

Dynamin-like MxA GTPase: Structural Insights into Oligomerization and Implications for Antiviral Activity

(2010) Otto Haller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GTPase activity is not essential for the interferon-inducible MxA protein to inhibit the replication of hepatitis B virus

(2008) Zhijian Yu et al.   ARCHIVES OF VIROLOGY

Influenza A Virus Strains Differ in Sensitivity to the Antiviral Action of Mx-GTPase

(2008) J. Dittmann et al.   JOURNAL OF VIROLOGY