Diagnostic value of serum biomarkers FGF21 and GDF15 compared to muscle sample in mitochondrial disease

Mitochondrial medicine in the omics era

(2018) Joyeeta Rahman et al.   LANCET

International Workshop:

(2017) Michelangelo Mancuso et al.   NEUROMUSCULAR DISORDERS

Use of FGF-21 as a Biomarker of Mitochondrial Disease in Clinical Practice

(2017) Alireza Morovat et al.   Journal of Clinical Medicine

Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism

(2016) Joni Nikkanen et al.   Cell Metabolism

Growth Differentiation Factor 15 Is a Novel Diagnostic Biomarker of Mitochondrial Diseases

(2016) Xinbo Ji et al.   MOLECULAR NEUROBIOLOGY

Elevated FGF 21 in myotonic dystrophy type 1 and mitochondrial diseases

(2016) Emese Lovadi et al.   MUSCLE & NERVE

FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders

(2016) Jenni M. Lehtonen et al.   NEUROLOGY

GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfunction

(2016) Raquel Montero et al.   PLoS One

Prevalence of nuclear and mitochondrial DNA mutations related to adult mitochondrial disease

(2015) Gráinne S. Gorman et al.   ANNALS OF NEUROLOGY

Growth differentiation factor 15 as a useful biomarker for mitochondrial disorders

(2015) Shuichi Yatsuga et al.   ANNALS OF NEUROLOGY

Growth Differentiation Factor-15 Is a Novel Biomarker Predicting Acute Exacerbation of Chronic Obstructive Pulmonary Disease

(2015) Levent Cem Mutlu et al.   INFLAMMATION

GDF15 is a novel biomarker to evaluate efficacy of pyruvate therapy for mitochondrial diseases

(2015) Yasunori Fujita et al.   MITOCHONDRION

Transcriptomic profiling of TK2 deficient human skeletal muscle suggests a role for the p53 signalling pathway and identifies growth and differentiation factor-15 as a potential novel biomarker for mitochondrial myopathies

(2014) Susana Kalko et al.   BMC GENOMICS

Serum FGF21 levels in adult m.3243A>G carriers: Clinical implications

(2014) S. Koene et al.   NEUROLOGY

Association of fibroblast growth factor (FGF-21) as a biomarker with primary mitochondrial disorders, but not with secondary mitochondrial disorders (Friedreich Ataxia)

(2013) Mohammad Hossein Salehi et al.   MOLECULAR BIOLOGY REPORTS

Fibroblast growth factor 21 is a sensitive biomarker of mitochondrial disease

(2013) R. L. Davis et al.   NEUROLOGY

Association of Growth Differentiation Factor-15 with Coronary Atherosclerosis and Mortality in a Young, Multiethnic Population: Observations from the Dallas Heart Study

(2011) A. Rohatgi et al.   CLINICAL CHEMISTRY

FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study

(2011) Anu Suomalainen et al.   LANCET NEUROLOGY

Growth differentiation factor-15 as a prognostic biomarker in ovarian cancer

(2010) Anne Cathrine Staff et al.   GYNECOLOGIC ONCOLOGY

Mitochondrial myopathy induces a starvation-like response

(2010) Henna Tyynismaa et al.   HUMAN MOLECULAR GENETICS

Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity

(2008) M. Mraz et al.   CLINICAL ENDOCRINOLOGY

Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans

(2008) X. Zhang et al.   DIABETES