GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfunction

Mutation loads in different tissues from six pathogenic mtDNA point mutations

(2015) María M. O'Callaghan et al.   MITOCHONDRION

GDF15 is a novel biomarker to evaluate efficacy of pyruvate therapy for mitochondrial diseases

(2015) Yasunori Fujita et al.   MITOCHONDRION

Diagnostic Approach in Infants and Children with Mitochondrial Diseases

(2015) Ching-Shiang Chi   Pediatrics and Neonatology

FGF21 expression and release in muscle cells: involvement of MyoD and regulation by mitochondria-driven signalling

(2014) Francesc Ribas et al.   BIOCHEMICAL JOURNAL

Transcriptomic profiling of TK2 deficient human skeletal muscle suggests a role for the p53 signalling pathway and identifies growth and differentiation factor-15 as a potential novel biomarker for mitochondrial myopathies

(2014) Susana Kalko et al.   BMC GENOMICS

Association between coenzyme Q10 and glucose transporter (GLUT1) deficiency

(2014) Delia Yubero et al.   BMC Pediatrics

Deoxypyrimidine monophosphate bypass therapy for thymidine kinase 2 deficiency

(2014) C. Garone et al.   EMBO Molecular Medicine

Growth Differentiation Factor-15 (GDF-15) Levels Are Associated with Cardiac and Renal Injury in Patients Undergoing Coronary Artery Bypass Grafting with Cardiopulmonary Bypass

(2014) Abdelkader Kahli et al.   PLoS One

The broadening spectrum of mitochondrial disease: Shifts in the diagnostic paradigm

(2013) Christina Liang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The clinical maze of mitochondrial neurology

(2013) Salvatore DiMauro et al.   Nature Reviews Neurology

Two In-and-out Modulation Strategies for Endoplasmic Reticulum Stress-linked Gene Expression of Pro-apoptotic Macrophage-inhibitory Cytokine 1

(2012) Seong-Hwan Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relation of Growth-Differentiation Factor 15 to Left Ventricular Remodeling in ST-Segment Elevation Myocardial Infarction

(2011) Alberto Dominguez-Rodriguez et al.   AMERICAN JOURNAL OF CARDIOLOGY

FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study

(2011) Anu Suomalainen et al.   LANCET NEUROLOGY

Neonatal muscular manifestations in mitochondrial disorders

(2011) Már Tulinius et al.   Seminars in Fetal & Neonatal Medicine

GDF-15 Contributes to Proliferation and Immune Escape of Malignant Gliomas

(2010) P. Roth et al.   CLINICAL CANCER RESEARCH

Plasma Growth Differentiation Factor-15 Independently Predicts All-Cause and Cardiovascular Mortality As Well As Deterioration of Kidney Function in Type 1 Diabetic Patients With Nephropathy

(2010) M. Lajer et al.   DIABETES CARE

Increased serum hepcidin and alterations in blood iron parameters associated with asymptomatic P. falciparum and P. vivax malaria

(2010) Q. de Mast et al.   HAEMATOLOGICA

Biochemical diagnosis of mitochondrial disorders

(2010) Richard J. T. Rodenburg   JOURNAL OF INHERITED METABOLIC DISEASE

Increased serum concentrations of macrophage inhibitory cytokine-1 in patients with obesity and type 2 diabetes mellitus: the influence of very low calorie diet

(2009) Ivana Dostálová et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Progressive Postnatal Motoneuron Loss in Mice Lacking GDF-15

(2009) J. Strelau et al.   JOURNAL OF NEUROSCIENCE

Next generation sequence analysis for mitochondrial disorders

(2009) Valeria Vasta et al.   Genome Medicine

The in-depth evaluation of suspected mitochondrial disease

(2008) Richard H. Haas et al.   MOLECULAR GENETICS AND METABOLISM