C-type lectin Mincle mediates cell death–triggered inflammation in acute kidney injury

Plaque-associated myeloid cells derive from resident microglia in an Alzheimer’s disease model

(2020) Erin G. Reed-Geaghan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Macrophages engulf apoptotic and primary necrotic thymocytes through similar phosphatidylserine-dependent mechanisms

(2019) Zsófia Budai et al.   FEBS Open Bio

Induction of autophagy through CLEC4E in combination with TLR4: an innovative strategy to restrict the survival of Mycobacterium tuberculosis

(2019) Susanta Pahari et al.   Autophagy

The pattern recognition receptors dectin-2, mincle, and FcRγ impact the dynamics of phagocytosis of Candida, Saccharomyces, Malassezia, and Mucor species

(2019) Mohammed Haider et al.   PLoS One

The Impact of Versatile Macrophage Functions on Acute Kidney Injury and Its Outcomes

(2019) Jea-Hyun Baek   Frontiers in Physiology

The role of non-resolving inflammation in atherosclerosis

(2018) Canan Kasikara et al.   JOURNAL OF CLINICAL INVESTIGATION

Mincle-Mediated Neutrophil Extracellular Trap Formation by Regulation of Autophagy

(2017) Atul Sharma et al.   JOURNAL OF INFECTIOUS DISEASES

The pattern recognition receptor, Mincle, is essential for maintaining the M1 macrophage phenotype in acute renal inflammation

(2017) Lin L. Lv et al.   KIDNEY INTERNATIONAL

Receptor Mincle promotes skin allergies and is capable of recognizing cholesterol sulfate

(2017) Alexey V. Kostarnoy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity

(2017) Masahiro Nagata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage Inducible C-Type Lectin As a Multifunctional Player in Immunity

(2017) Emmanuel C. Patin et al.   Frontiers in Immunology

Trehalose dimycolate interferes with FcγR-mediated phagosome maturation through Mincle, SHP-1 and FcγRIIB signalling

(2017) Emmanuel C. Patin et al.   PLoS One

IRAKM-Mincle axis links cell death to inflammation: Pathophysiological implications for chronic alcoholic liver disease

(2016) Hao Zhou et al.   HEPATOLOGY

Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction

(2016) Michio Nakaya et al.   JOURNAL OF CLINICAL INVESTIGATION

Mincle Signaling Promotes Con A Hepatitis

(2016) Stephanie H. Greco et al.   JOURNAL OF IMMUNOLOGY

The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression

(2016) Lena Seifert et al.   NATURE

CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis

(2016) Yoko Kojima et al.   NATURE

Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice

(2016) Satoko Arai et al.   NATURE MEDICINE

C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia

(2016) Friederike Behler-Janbeck et al.   PLoS Pathogens

Human Mincle Binds to Cholesterol Crystals and Triggers Innate Immune Responses

(2015) Ryoko Kiyotake et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C-Type Lectin Receptor MCL Facilitates Mincle Expression and Signaling through Complex Formation

(2015) Yasunobu Miyake et al.   JOURNAL OF IMMUNOLOGY

Differential Ly6C Expression after Renal Ischemia-Reperfusion Identifies Unique Macrophage Populations

(2015) M. Clements et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Necroinflammation in Kidney Disease

(2015) S. R. Mulay et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD

(2015) David A. Ferenbach et al.   Nature Reviews Nephrology

LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling

(2015) Ayaka Ito et al.   eLife

The Macrophage-Inducible C-Type Lectin, Mincle, Is an Essential Component of the Innate Immune Response to Candida albicans

(2014) C. A. Wells et al.   JOURNAL OF IMMUNOLOGY

Regulated Cell Death in AKI

(2014) A. Linkermann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Macrophage-mediated injury and repair after ischemic kidney injury

(2014) Sarah C. Huen et al.   PEDIATRIC NEPHROLOGY

Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis

(2014) Miyako Tanaka et al.   Nature Communications

Bax and Bak have critical roles in ischemic acute kidney injury in global and proximal tubule–specific knockout mouse models

(2013) Qingqing Wei et al.   KIDNEY INTERNATIONAL

Hepatic Crown-Like Structure: A Unique Histological Feature in Non-Alcoholic Steatohepatitis in Mice and Humans

(2013) Michiko Itoh et al.   PLoS One

Neutrophils Promote Mycobacterial Trehalose Dimycolate-Induced Lung Inflammation via the Mincle Pathway

(2012) Wook-Bin Lee et al.   PLoS Pathogens

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

(2011) S. Lee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Two-Step Engulfment of Apoptotic Cells

(2011) S. Toda et al.   MOLECULAR AND CELLULAR BIOLOGY

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

(2009) Eri Ishikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

C-type lectin Mincle is an activating receptor for pathogenic fungus,Malassezia

(2009) Sho Yamasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes

(2008) C. N. Lumeng et al.   DIABETES

Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice

(2008) I. Murano et al.   JOURNAL OF LIPID RESEARCH

ATF3 Protects against Renal Ischemia-Reperfusion Injury

(2008) T. Yoshida et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mincle is an ITAM-coupled activating receptor that senses damaged cells

(2008) Sho Yamasaki et al.   NATURE IMMUNOLOGY