Trehalose dimycolate interferes with FcγR-mediated phagosome maturation through Mincle, SHP-1 and FcγRIIB signalling

Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection

(2016) Salvador Iborra et al.   IMMUNITY

Fc  Receptors Regulate Immune Activation and Susceptibility during Mycobacterium tuberculosis Infection

(2014) P. J. Maglione et al.   JOURNAL OF IMMUNOLOGY

The Macrophage-Inducible C-Type Lectin, Mincle, Is an Essential Component of the Innate Immune Response to Candida albicans

(2014) C. A. Wells et al.   JOURNAL OF IMMUNOLOGY

The Human Antibody Response to the Surface of Mycobacterium tuberculosis

(2014) Casey C. Perley et al.   PLoS One

C-type Lectin MCL Is an FcRγ-Coupled Receptor that Mediates the Adjuvanticity of Mycobacterial Cord Factor

(2013) Yasunobu Miyake et al.   IMMUNITY

Protective Role of Mincle in Bacterial Pneumonia by Regulation of Neutrophil Mediated Phagocytosis and Extracellular Trap Formation

(2013) A. Sharma et al.   JOURNAL OF INFECTIOUS DISEASES

Diversion of phagosome trafficking by pathogenicRhodococcus equidepends on mycolic acid chain length

(2012) Tobias Sydor et al.   CELLULAR MICROBIOLOGY

The Protein Tyrosine Phosphatase SHP-1 Regulates Phagolysosome Biogenesis

(2012) C. P. Gomez et al.   JOURNAL OF IMMUNOLOGY

Role of Mincle in Alveolar Macrophage-Dependent Innate Immunity against Mycobacterial Infections in Mice

(2012) F. Behler et al.   JOURNAL OF IMMUNOLOGY

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

(2012) Christian M Karsten et al.   NATURE MEDICINE

Interferon Gamma Activated Macrophages Kill Mycobacteria by Nitric Oxide Induced Apoptosis

(2011) Susanne Herbst et al.   PLoS One

Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate

(2010) H. Schoenen et al.   JOURNAL OF IMMUNOLOGY

Protein tyrosine phosphatase SHP-1 positively regulates TLR-induced IL-12p40 production in macrophages through inhibition of phosphatidylinositol 3-kinase

(2010) Delu Zhou et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Adjuvanticity of a synthetic cord factor analogue for subunitMycobacterium tuberculosisvaccination requires FcRγ–Syk–Card9–dependent innate immune activation

(2009) Kerstin Werninghaus et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

(2009) Eri Ishikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

C-type lectin Mincle is an activating receptor for pathogenic fungus,Malassezia

(2009) Sho Yamasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TB Research at UT-Houston – A review of cord factor: new approaches to drugs, vaccines and the pathogenesis of tuberculosis

(2009) Robert L. Hunter et al.   TUBERCULOSIS

Delay of phagosome maturation by a mycobacterial lipid is reversed by nitric oxide

(2008) Sofia Axelrod et al.   CELLULAR MICROBIOLOGY

Mincle is an ITAM-coupled activating receptor that senses damaged cells

(2008) Sho Yamasaki et al.   NATURE IMMUNOLOGY