HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus
Authors
Keywords
-
Journal
JOURNAL OF CLINICAL INVESTIGATION
Volume -, Issue -, Pages -
Publisher
American Society for Clinical Investigation
Online
2020-10-05
DOI
10.1172/jci138099
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A Simpler and More Sensitive Single Copy HIV-1 RNA Assay to Quantify Persistent HIV-1 Viremia in Individuals on Suppressive Antiretroviral Therapy
- (2019) Melissa A. Tosiano et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy
- (2019) Kevin B. Einkauf et al. JOURNAL OF CLINICAL INVESTIGATION
- HIV Proviral Sequence Database (PSD): A New Public Database for Near Full-Length HIV Proviral Sequences and Their Meta-Analyses
- (2019) Wei Shao et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- HIV Rebound Is Predominantly Fueled by Genetically Identical Viral Expansions from Diverse Reservoirs
- (2019) Marie-Angélique De Scheerder et al. Cell Host & Microbe
- HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy
- (2019) William R. McManus et al. JOURNAL OF CLINICAL INVESTIGATION
- HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus
- (2019) Andrew Musick et al. Frontiers in Microbiology
- Changes in the NK Cell Repertoire Related to Initiation of TB Treatment and Onset of Immune Reconstitution Inflammatory Syndrome in TB/HIV Co-infected Patients in Rio de Janeiro, Brazil—ANRS 12274
- (2019) Carmem Beatriz Wagner Giacoia-Gripp et al. Frontiers in Immunology
- Establishment of normative ranges of the healthy human immune system with comprehensive polychromatic flow cytometry profiling
- (2019) John S. Yi et al. PLoS One
- Relationship between latent and rebound viruses in a clinical trial of anti–HIV-1 antibody 3BNC117
- (2018) Yehuda Z. Cohen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Combination therapy with anti-HIV-1 antibodies maintains viral suppression
- (2018) Pilar Mendoza et al. NATURE
- Proliferation of latently infected CD4+T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics
- (2017) Nina N. Hosmane et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART
- (2017) Ann Wiegand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Boceprevir and Antiretroviral Pharmacokinetic Interactions in HIV/HCV Co-infected Persons: AIDS Clinical Trials Group Study A5309s
- (2017) Jennifer J. Kiser et al. Drugs in research & development
- Ex vivo activation of CD4+ T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells
- (2017) John K. Bui et al. PLoS Pathogens
- Levels of HIV-1 persistence on antiretroviral therapy are not associated with markers of inflammation or activation
- (2017) Rajesh T. Gandhi et al. PLoS Pathogens
- Novel Assays for Measurement of Total Cell-Associated HIV-1 DNA and RNA
- (2016) Feiyu Hong et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Defective proviruses rapidly accumulate during acute HIV-1 infection
- (2016) Katherine M Bruner et al. NATURE MEDICINE
- Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA
- (2016) Julio C. C. Lorenzi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clonally expanded CD4+T cells can produce infectious HIV-1 in vivo
- (2016) Francesco R. Simonetti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Origin of Rebound Plasma HIV Includes Cells with Identical Proviruses That Are Transcriptionally Active before Stopping of Antiretroviral Therapy
- (2015) Mary F. Kearney et al. JOURNAL OF VIROLOGY
- Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1
- (2015) Daniel I. S. Rosenbloom et al. Open Forum Infectious Diseases
- Analysis of CD4+CD8+double-positive T cells in blood, cerebrospinal fluid and multiple sclerosis lesions
- (2014) A. Waschbisch et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Improved Single-Copy Assays for Quantification of Persistent HIV-1 Viremia in Patients on Suppressive Antiretroviral Therapy
- (2014) A. R. Cillo et al. JOURNAL OF CLINICAL MICROBIOLOGY
- CD4+ /CD8+ double-positive T cells: more than just a developmental stage?
- (2014) Nana H. Overgaard et al. JOURNAL OF LEUKOCYTE BIOLOGY
- High Frequencies of Polyfunctional CD8+ NK Cells in Chronic HIV-1 Infection Are Associated with Slower Disease Progression
- (2014) F. Ahmad et al. JOURNAL OF VIROLOGY
- Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection
- (2014) T. A. Wagner et al. SCIENCE
- Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
- (2014) F. Maldarelli et al. SCIENCE
- Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
- (2013) Ya-Chi Ho et al. CELL
- A sensitive HPLC–MS/MS method for the determination of dolutegravir in human plasma
- (2013) Chantelle Bennetto-Hood et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0
- (2013) Koichiro Tamura et al. MOLECULAR BIOLOGY AND EVOLUTION
- Short‐Course Raltegravir Intensification Does Not Reduce Persistent Low‐Level Viremia in Patients with HIV‐1 Suppression during Receipt of Combination Antiretroviral Therapy
- (2010) D. McMahon et al. CLINICAL INFECTIOUS DISEASES
- The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial
- (2010) Rajesh T. Gandhi et al. PLOS MEDICINE
- Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
- (2009) Jesus F. Salazar-Gonzalez et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy
- (2009) J. B. Dinoso et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A procedure for highly specific, sensitive, and unbiased whole-genome amplification
- (2008) X. Pan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HIV rebounds from latently infected cells, rather than from continuing low-level replication
- (2008) B. Joos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started