Relationship between latent and rebound viruses in a clinical trial of anti–HIV-1 antibody 3BNC117

Fitness landscape of the human immunodeficiency virus envelope protein that is targeted by antibodies

(2018) Raymond H. Y. Louie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane

(2018) Zheng Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection

(2018) Hongshuo Song et al.   Nature Communications

Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells

(2017) Guinevere Q. Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Proliferation of latently infected CD4+T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics

(2017) Nina N. Hosmane et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutralizing Activity of Broadly Neutralizing Anti-HIV-1 Antibodies against Clade B Clinical Isolates Produced in Peripheral Blood Mononuclear Cells

(2017) Yehuda Z. Cohen et al.   JOURNAL OF VIROLOGY

Improved Algorithmic Complexity for the 3SEQ Recombination Detection Algorithm

(2017) Ha Minh Lam et al.   MOLECULAR BIOLOGY AND EVOLUTION

Early antibody therapy can induce long-lasting immunity to SHIV

(2017) Yoshiaki Nishimura et al.   NATURE

Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

(2017) Marina Caskey et al.   NATURE MEDICINE

Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir

(2017) John K. Bui et al.   PLoS Pathogens

Progress Toward HIV Eradication: Case Reports, Current Efforts, and the Challenges Associated with Cure

(2016) Alyssa R. Martin et al.   Annual Review of Medicine

Towards HIV-1 remission: potential roles for broadly neutralizing antibodies

(2016) Ariel Halper-Stromberg et al.   JOURNAL OF CLINICAL INVESTIGATION

HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption

(2016) Johannes F. Scheid et al.   NATURE

A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges

(2016) Rajeev Gautam et al.   NATURE

Defective proviruses rapidly accumulate during acute HIV-1 infection

(2016) Katherine M Bruner et al.   NATURE MEDICINE

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption

(2016) Katharine J. Bar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA

(2016) Julio C. C. Lorenzi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo

(2016) C.-L. Lu et al.   SCIENCE

Experimental Estimation of the Effects of All Amino-Acid Mutations to HIV’s Envelope Protein on Viral Replication in Cell Culture

(2016) Hugh K. Haddox et al.   PLoS Pathogens

HIV-1 Integration Landscape during Latent and Active Infection

(2015) Lillian B. Cohn et al.   CELL

Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies

(2015) Amanda M. Crooks et al.   JOURNAL OF INFECTIOUS DISEASES

Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117

(2015) Marina Caskey et al.   NATURE

HIV reservoirs: what, where and how to target them

(2015) Melissa J. Churchill et al.   NATURE REVIEWS MICROBIOLOGY

Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection

(2015) Rebecca M. Lynch et al.   Science Translational Medicine

Recombination Enhances HIV-1 Envelope Diversity by Facilitating the Survival of Latent Genomic Fragments in the Plasma Virus Population

(2015) Taina T. Immonen et al.   PLoS Computational Biology

Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1

(2015) Daniel I. S. Rosenbloom et al.   Open Forum Infectious Diseases

Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice

(2014) Ariel Halper-Stromberg et al.   CELL

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

(2014) Masashi Shingai et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1

(2014) Alison L. Hill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection

(2014) Adam John Ritchie et al.   Retrovirology

Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

(2013) Ya-Chi Ho et al.   CELL

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

(2013) Tongqing Zhou et al.   IMMUNITY

Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1

(2013) Marcella Sarzotti-Kelsoe et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Dynamics of Viral Evolution and Neutralizing Antibody Response after HIV-1 Superinfection

(2013) Antoine Chaillon et al.   JOURNAL OF VIROLOGY

Multiple Pathways of Escape from HIV Broadly Cross-Neutralizing V2-Dependent Antibodies

(2013) P. L. Moore et al.   JOURNAL OF VIROLOGY

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia

(2013) Masashi Shingai et al.   NATURE

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

(2013) Dan H. Barouch et al.   NATURE

HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

(2013) J. A. Horwitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice

(2012) Florian Klein et al.   NATURE

Estimate of effective recombination rate and average selection coefficient for HIV in chronic infection

(2011) R. Batorsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

(2011) J. F. Scheid et al.   SCIENCE

Viral Mutation Rates

(2010) R. Sanjuan et al.   JOURNAL OF VIROLOGY

Nature, Position, and Frequency of Mutations Made in a Single Cycle of HIV-1 Replication

(2010) M. E. Abram et al.   JOURNAL OF VIROLOGY

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

Recombination Rate and Selection Strength in HIV Intra-patient Evolution

(2010) Richard A. Neher et al.   PLoS Computational Biology

Immune-driven recombination and loss of control after HIV superinfection

(2008) Hendrik Streeck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Deciphering Human Immunodeficiency Virus Type 1 Transmission and Early Envelope Diversification by Single-Genome Amplification and Sequencing

(2008) J. F. Salazar-Gonzalez et al.   JOURNAL OF VIROLOGY