DNMT1 deregulation of SOCS3 axis drives cardiac fibroblast activation in diabetic cardiac fibrosis

Alcohol promotes renal fibrosis by activating Nox2/4-mediated DNA methylation of Smad7

(2020) Qin Yang et al.   CLINICAL SCIENCE

TRPV4 Mediates Cardiac Fibrosis via the TGF-β1/Smad3 Signaling Pathway in Diabetic Rats

(2020) Xiaoli Jia et al.   Cardiovascular Toxicology

Basic Mechanisms of Diabetic Heart Disease

(2020) Rebecca H. Ritchie et al.   CIRCULATION RESEARCH

TGF-β–induced epigenetic deregulation of SOCS3 facilitates STAT3 signaling to promote fibrosis

(2020) Clara Dees et al.   JOURNAL OF CLINICAL INVESTIGATION

CCL20 induced by visfatin in macrophages via the NF-κB and MKK3/6-p38 signaling pathways contributes to hepatic stellate cell activation

(2020) Yu Jung Heo et al.   MOLECULAR BIOLOGY REPORTS

Chimeric Peptidomimetics of SOCS 3 Able to Interact with JAK2 as Anti-inflammatory Compounds

(2020) Sara La Manna et al.   ACS Medicinal Chemistry Letters

The Extracellular Matrix in Ischemic and Nonischemic Heart Failure

(2019) Nikolaos G. Frangogiannis   CIRCULATION RESEARCH

Resveratrol suppresses the myofibroblastic phenotype and fibrosis formation in kidneys via proliferation‐related signalling pathways

(2019) Xing Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of EGFR-STAT3 attenuates cardiomyopathy in streptozotocin-induced type 1 diabetes

(2019) Wu Luo et al.   JOURNAL OF ENDOCRINOLOGY

Mesoporous Silica Nanoparticles Trigger Liver and Kidney Injury and Fibrosis Via Altering TLR4/NF-κB, JAK2/STAT3 and Nrf2/HO-1 Signaling in Rats

(2019) Ayman M. Mahmoud et al.   Biomolecules

Role of Mammalian DNA Methyltransferases in Development

(2019) Zhiyuan Chen et al.   Annual Review of Biochemistry

MiR-340 affects gastric cancer cell proliferation, cycle, and apoptosis through regulating SOCS3/JAK-STAT signaling pathway

(2018) Chunhong Xiao et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1

(2018) Yingfeng Li et al.   NATURE

Long noncoding AGAP2-AS1 is activated by SP1 and promotes cell proliferation and invasion in gastric cancer

(2017) Fuzhen Qi et al.   Journal of Hematology & Oncology

Association of Cardiovascular Risk Factors and Myocardial Fibrosis With Early Cardiac Dysfunction in Type 1 Diabetes: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study

(2016) Anderson C. Armstrong et al.   DIABETES CARE

LCZ696, an angiotensin receptor-neprilysin inhibitor, improves cardiac function with the attenuation of fibrosis in heart failure with reduced ejection fraction in streptozotocin-induced diabetic mice

(2016) Yasunori Suematsu et al.   EUROPEAN JOURNAL OF HEART FAILURE

Non-coding RNAs as direct and indirect modulators of epigenetic mechanism regulation of cardiac fibrosis

(2015) Hui Tao et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Suppressor of Cytokine Signaling (SOCS) Genes Are Silenced by DNA Hypermethylation and Histone Deacetylation and Regulate Response to Radiotherapy in Cervical Cancer Cells

(2015) Moon-Hong Kim et al.   PLoS One

DNMT3A silencing RASSF1A promotes cardiac fibrosis through upregulation of ERK1/2

(2014) Hui Tao et al.   TOXICOLOGY

Transforming Growth Factor β1 Induces the Expression of Collagen Type I by DNA Methylation in Cardiac Fibroblasts

(2013) Xiaodong Pan et al.   PLoS One

Fasudil hydrochloride hydrate, a Rho-kinase inhibitor, suppresses high glucose-induced proliferation and collagen synthesis in rat cardiac fibroblasts

(2011) Hong Zhou et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY