α‐Mangostin‐encapsulated PLGA nanoparticles inhibit colorectal cancer growth by inhibiting Notch pathway

Colorectal cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Inhibition of pancreatic cancer stem cell characteristics by α‐Mangostin: Molecular mechanisms involving Sonic hedgehog and Nanog

(2019) Yiming Ma et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis

(2019) Rene Jackstadt et al.   CANCER CELL

Notch Signaling in the Tumor Microenvironment

(2018) Olivier Meurette et al.   CANCER CELL

Notch and its oncogenic activity in human malignancies

(2017) Marlena Brzozowa-Zasada et al.   European Surgery-Acta Chirurgica Austriaca

SATB2/β-catenin/TCF-LEF pathway induces cellular transformation by generating cancer stem cells in colorectal cancer

(2017) Wei Yu et al.   Scientific Reports

Delivery of tanshinone IIA and α-mangostin from gold/PEI/cyclodextrin nanoparticle platform designed for prostate cancer chemotherapy

(2016) Shihong Qiu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antiproliferative and apoptosis induction of α-mangostin in T47D breast cancer cells

(2016) SOMCHAI KRITSANAWONG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

α-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in human, and transgenic (KrasG12D, and KrasG12D/tp53R270H) mice

(2016) Raj Kumar Verma et al.   Scientific Reports

Recent advances in pancreatic cancer: biology, treatment, and prevention

(2015) Divya Singh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

A Tumor Suppressor Function for Notch Signaling in Forebrain Tumor Subtypes

(2015) Claudio Giachino et al.   CANCER CELL

Network biology elucidates metastatic colon cancer mechanisms

(2015) Inna Kuperstein et al.   CELL CYCLE

Notch-1 Promotes Stemness and Epithelial to Mesenchymal Transition in Colorectal Cancer

(2015) Alexander W. Fender et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Anthothecol-encapsulated PLGA nanoparticles inhibit pancreatic cancer stem cell growth by modulating sonic hedgehog pathway

(2015) Raj Kumar Verma et al.   Nanomedicine-Nanotechnology Biology and Medicine

PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth

(2015) Narinder Sharma et al.   Oncotarget

α-Mangostin suppresses human gastric adenocarcinoma cells in vitro via blockade of Stat3 signaling pathway

(2014) Tao Shan et al.   ACTA PHARMACOLOGICA SINICA

From Fly Wings to Targeted Cancer Therapies: A Centennial for Notch Signaling

(2014) Panagiotis Ntziachristos et al.   CANCER CELL

Anti-angiogenic actions of the mangosteen polyphenolic xanthone derivative α-mangostin

(2014) Kanjana Jittiporn et al.   MICROVASCULAR RESEARCH

Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer

(2014) Y Dai et al.   Cell Death & Disease

α-Mangostin: A Dietary Antioxidant Derived from the Pericarp of Garcinia mangostana L. Inhibits Pancreatic Tumor Growth in Xenograft Mouse Model

(2013) Bilal Bin Hafeez et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibitory effects of α-mangostin on mammalian DNA polymerase, topoisomerase, and human cancer cell proliferation

(2013) Yoshiyuki Mizushina et al.   FOOD AND CHEMICAL TOXICOLOGY

Developmental signaling pathways in cancer stem cells of solid tumors

(2012) Christina Karamboulas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog–GLI pathway

(2012) Shih-Hui Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Therapeutic approaches to modulating Notch signaling: Current challenges and future prospects

(2012) Casper Groth et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications

(2011) Brahma N. Singh et al.   BIOCHEMICAL PHARMACOLOGY

Suppression of Colon Cancer Metastasis by Aes through Inhibition of Notch Signaling

(2011) Masahiro Sonoshita et al.   CANCER CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells

(2011) K. L. VanDussen et al.   DEVELOPMENT

Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics

(2011) Su-Ni Tang et al.   INTERNATIONAL JOURNAL OF CANCER

Hedgehog Signaling Antagonist GDC-0449 (Vismodegib) Inhibits Pancreatic Cancer Stem Cell Characteristics: Molecular Mechanisms

(2011) Brahma N. Singh et al.   PLoS One

Biology of Colorectal Cancer

(2010) Muhammad Wasif Saif et al.   CANCER JOURNAL

NOTCH Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer

(2010) S. S. Sikandar et al.   CANCER RESEARCH

 -Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity

(2009) R. D. Meng et al.   CANCER RESEARCH

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Colon cancer stem cells

(2009) Lucia Ricci-Vitiani et al.   JOURNAL OF MOLECULAR MEDICINE-JMM