Rabgap1 promotes recycling of active β1 integrins to support effective cell migration

Complex Rab4-Mediated Regulation of Endosomal Size and EGFR Activation

(2020) Kate Tubbesing et al.   MOLECULAR CANCER RESEARCH

GGA2 and RAB13 promote activity-dependent β1-integrin recycling

(2019) Pranshu Sahgal et al.   JOURNAL OF CELL SCIENCE

TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling

(2018) Natsumi Kawasaki et al.   Cell Discovery

Integrin trafficking in cells and tissues

(2018) Paulina Moreno-Layseca et al.   NATURE CELL BIOLOGY

Integrin activation by talin, kindlin and mechanical forces

(2018) Zhiqi Sun et al.   NATURE CELL BIOLOGY

Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading

(2017) Ralph T. Böttcher et al.   JOURNAL OF CELL BIOLOGY

Integrin extension enables ultrasensitive regulation by cytoskeletal force

(2017) Jing Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An improved smaller biotin ligase for BioID proximity labeling

(2016) Dae In Kim et al.   MOLECULAR BIOLOGY OF THE CELL

FAK, talin and PIPKIγ regulate endocytosed integrin activation to polarize focal adhesion assembly

(2016) Guilherme P. F. Nader et al.   NATURE CELL BIOLOGY

Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation

(2016) Zhiqi Sun et al.   NATURE CELL BIOLOGY

Relating conformation to function in integrin α5β1

(2016) Yang Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis

(2016) Giulia Mana et al.   Nature Communications

Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin

(2016) Marina Theodosiou et al.   eLife

α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3

(2015) Nikki R. Paul et al.   JOURNAL OF CELL BIOLOGY

Integrin traffic - the update

(2015) N. De Franceschi et al.   JOURNAL OF CELL SCIENCE

Persistent cell migration and adhesion rely on retrograde transport of β1 integrin

(2015) Massiullah Shafaq-Zadah et al.   NATURE CELL BIOLOGY

Integrin endosomal signalling suppresses anoikis

(2015) Jonna Alanko et al.   NATURE CELL BIOLOGY

Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration

(2015) Dmitri Kharitidi et al.   Cell Reports

Ligand-Occupied Integrin Internalization Links Nutrient Signaling to Invasive Migration

(2015) Elena Rainero et al.   Cell Reports

PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function

(2014) Irene Franco et al.   DEVELOPMENTAL CELL

Sorting Nexin 31 Binds Multiple β Integrin Cytoplasmic Domains and Regulates β1 Integrin Surface Levels and Stability

(2014) Hui-Yuan Tseng et al.   JOURNAL OF MOLECULAR BIOLOGY

The integrin adhesome: from genes and proteins to human disease

(2014) Sabina E. Winograd-Katz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Skin-depth Analysis of Integrins: Role of the Integrin Network in Health and Disease

(2013) Samarth Hegde et al.   CELL COMMUNICATION AND ADHESION

Complete integrin headpiece opening in eight steps

(2013) Jieqing Zhu et al.   JOURNAL OF CELL BIOLOGY

Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway

(2013) G. Jacquemet et al.   JOURNAL OF CELL SCIENCE

β1 Integrins with Individually Disrupted Cytoplasmic NPxY Motifs Are Embryonic Lethal but Partially Active in the Epidermis

(2013) Alexander Meves et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Integrins in Kidney Disease

(2013) A. Pozzi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

(2013) Herbert B. Schiller et al.   NATURE CELL BIOLOGY

Talins and kindlins: partners in integrin-mediated adhesion

(2013) David A. Calderwood et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Rab Interacting Lysosomal Protein (RILP) Homology Domain Functions as a Novel Effector Domain for Small GTPase Rab36

(2012) Takahide Matsui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathways

(2012) Florian Steinberg et al.   JOURNAL OF CELL BIOLOGY

Induction of membrane circular dorsal ruffles requires co-signalling of integrin-ILK-complex and EGF receptor

(2012) S. B. Azimifar et al.   JOURNAL OF CELL SCIENCE

Sorting nexin 17 prevents lysosomal degradation of β1 integrins by binding to the β1-integrin tail

(2012) Ralph Thomas Böttcher et al.   NATURE CELL BIOLOGY

Illuminating the functional and structural repertoire of human TBC/RABGAPs

(2012) Marieke A. M. Frasa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Distinct Recycling of Active and Inactive β1 Integrins

(2012) Antti Arjonen et al.   TRAFFIC

Rab25 and CLIC3 Collaborate to Promote Integrin Recycling from Late Endosomes/Lysosomes and Drive Cancer Progression

(2011) Marta A. Dozynkiewicz et al.   DEVELOPMENTAL CELL

Rab11 is required for cell adhesion, maintenance of cell shape and actin-cytoskeleton organization during Drosophila wing development

(2011) Tanmay Bhuin et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Competitive binding of Rab21 and p120RasGAP to integrins regulates receptor traffic and migration

(2011) Anja Mai et al.   JOURNAL OF CELL BIOLOGY

 1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation

(2011) A. Meves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ubiquitination of α5β1 Integrin Controls Fibroblast Migration through Lysosomal Degradation of Fibronectin-Integrin Complexes

(2010) Viola Hélène Lobert et al.   DEVELOPMENTAL CELL

Recreation of the terminal events in physiological integrin activation

(2010) Feng Ye et al.   JOURNAL OF CELL BIOLOGY

Comprehensive Screening for Novel Rab-Binding Proteins by GST Pull-Down Assay Using 60 Different Mammalian Rabs‡

(2010) Eiko Kanno et al.   TRAFFIC

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

Focal adhesion disassembly requires clathrin-dependent endocytosis of integrins

(2009) Wei-Ting Chao et al.   FEBS LETTERS

Rab36 regulates the spatial distribution of late endosomes and lysosomes through a similar mechanism to Rab34

(2009) Li Chen et al.   MOLECULAR MEMBRANE BIOLOGY

Integrins: masters and slaves of endocytic transport

(2009) Patrick T. Caswell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Tail of Integrins, Talin, and Kindlins

(2009) M. Moser et al.   SCIENCE

Neuropilin-1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells

(2009) Donatella Valdembri et al.   PLOS BIOLOGY

Rab-coupling protein coordinates recycling of α5β1 integrin and EGFR1 to promote cell migration in 3D microenvironments

(2008) Patrick T. Caswell et al.   JOURNAL OF CELL BIOLOGY