CDC42EP5/BORG3 modulates SEPT9 to promote actomyosin function, migration, and invasion

Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment

(2019) Mirella Georgouli et al.   CELL

Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions

(2019) Jenna Marcus et al.   ONCOGENE

Focal Adhesion–Independent Cell Migration

(2016) Ewa K. Paluch et al.   Annual Review of Cell and Developmental Biology

The Borg family of Cdc42 effector proteins Cdc42EP1-5

(2016) A. J. Farrugia et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Modes of invasion during tumour dissemination

(2016) Pahini Pandya et al.   Molecular Oncology

The requirement of SEPT2 and SEPT7 for migration and invasion in human breast cancer via MEK/ERK activation

(2016) Nianzhu Zhang et al.   Oncotarget

Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis

(2016) Sandra Kümper et al.   eLife

Septin 9 Exhibits Polymorphic Binding to F-Actin and Inhibits Myosin and Cofilin Activity

(2015) Clayton Smith et al.   JOURNAL OF MOLECULAR BIOLOGY

Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts

(2015) Fernando Calvo et al.   Cell Reports

Phosphorylation of Cdc42 Effector Protein-4 (CEP4) by Protein Kinase C Promotes Motility of Human Breast Cells

(2014) Xin Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Septins promote stress fiber–mediated maturation of focal adhesions and renal epithelial motility

(2014) Lee Dolat et al.   JOURNAL OF CELL BIOLOGY

Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells

(2014) Zhonghua Liu et al.   MOLECULAR BIOLOGY OF THE CELL

The melanoma revolution: From UV carcinogenesis to a new era in therapeutics

(2014) J. A. Lo et al.   SCIENCE

Diverse matrix metalloproteinase functions regulate cancer amoeboid migration

(2014) Jose L. Orgaz et al.   Nature Communications

The tension mounts: Stress fibers as force-generating mechanotransducers

(2013) Keith Burridge et al.   JOURNAL OF CELL BIOLOGY

Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions

(2013) Melda Tozluoğlu et al.   NATURE CELL BIOLOGY

The septin cytoskeleton facilitates membrane retraction during motility and blebbing

(2012) Julia K. Gilden et al.   JOURNAL OF CELL BIOLOGY

Actin-bundling proteins in cancer progression at a glance

(2012) R. P. Stevenson et al.   JOURNAL OF CELL SCIENCE

Septins: the fourth component of the cytoskeleton

(2012) Serge Mostowy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural and biochemical properties of Sept7, a unique septin required for filament formation

(2011) Eldar Zent et al.   BIOLOGICAL CHEMISTRY

ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma

(2011) Victoria Sanz-Moreno et al.   CANCER CELL

SEPT9 occupies the terminal positions in septin octamers and mediates polymerization-dependent functions in abscission

(2011) Moshe S. Kim et al.   JOURNAL OF CELL BIOLOGY

RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation

(2011) Fernando Calvo et al.   NATURE CELL BIOLOGY

The plasticity of cytoskeletal dynamics underlying neoplastic cell migration

(2010) Victoria Sanz-Moreno et al.   CURRENT OPINION IN CELL BIOLOGY

Cancer Dissemination—Lessons from Leukocytes

(2010) Chris D. Madsen et al.   DEVELOPMENTAL CELL

Distinct roles of septins in cytokinesis: SEPT9 mediates midbody abscission

(2010) Mathew P. Estey et al.   JOURNAL OF CELL BIOLOGY

Oncogenic Braf Induces Melanocyte Senescence and Melanoma in Mice

(2009) Nathalie Dhomen et al.   CANCER CELL

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms guiding primordial germ cell migration: strategies from different organisms

(2009) Brian E. Richardson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis

(2008) Adam I Riker et al.   BMC Medical Genomics

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner

(2008) Colin K. Choi et al.   NATURE CELL BIOLOGY

Amoeboid T lymphocytes require the septin cytoskeleton for cortical integrity and persistent motility

(2008) Aaron J. Tooley et al.   NATURE CELL BIOLOGY