Nanomedicine for Ischemic Stroke

Platelet Membrane Biomimetic Magnetic Nanocarriers for Targeted Delivery and in Situ Generation of Nitric Oxide in Early Ischemic Stroke

(2020) Mingxi Li et al.   ACS Nano

Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association

(2020) Salim S. Virani et al.   CIRCULATION

Targeting Strategies for Tissue-Specific Drug Delivery

(2020) Zongmin Zhao et al.   CELL

Molecular Dynamics Simulations Provide Insight into the Loading Efficiency of Proresolving Lipid Mediators Resolvin D1 and D2 in Cell Membrane-Derived Nanovesicles

(2020) Jeevan B. GC et al.   MOLECULAR PHARMACEUTICS

Neutrophil Membrane-Derived Nanovesicles Alleviate Inflammation To Protect Mouse Brain Injury from Ischemic Stroke

(2019) Xinyue Dong et al.   ACS Nano

Selective Liposomal Transport through Blood Brain Barrier Disruption in Ischemic Stroke Reveals Two Distinct Therapeutic Opportunities

(2019) Zahraa S. Al-Ahmady et al.   ACS Nano

Nanoparticle-induced neutrophil apoptosis increases survival in sepsis and alleviates neurological damage in stroke

(2019) Can Yang Zhang et al.   Science Advances

Bioinspired Nanosponge for Salvaging Ischemic Stroke via Free Radical Scavenging and Self-Adapted Oxygen Regulating

(2019) Jinjin Shi et al.   NANO LETTERS

Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

(2019) William J. Powers et al.   STROKE

Bioengineered Boronic Ester Modified Dextran Polymer Nanoparticles as Reactive Oxygen Species Responsive Nanocarrier for Ischemic Stroke Treatment

(2018) Wei Lv et al.   ACS Nano

Simultaneous Blood–Brain Barrier Crossing and Protection for Stroke Treatment Based on Edaravone-Loaded Ceria Nanoparticles

(2018) Qunqun Bao et al.   ACS Nano

Neutrophil-Based Drug Delivery Systems

(2018) Dafeng Chu et al.   ADVANCED MATERIALS

Cell Membrane Coating Nanotechnology

(2018) Ronnie H. Fang et al.   ADVANCED MATERIALS

Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy

(2018) Tian Tian et al.   BIOMATERIALS

Reperfusion therapy in acute ischemic stroke: dawn of a new era?

(2018) Sonu Bhaskar et al.   BMC Neurology

Challenges and opportunities in stroke genetics

(2018) Rainer Malik et al.   CARDIOVASCULAR RESEARCH

Free Radical Damage in Ischemia-Reperfusion Injury: An Obstacle in Acute Ischemic Stroke after Revascularization Therapy

(2018) Ming-Shuo Sun et al.   Oxidative Medicine and Cellular Longevity

Recent Advances in the Therapeutic and Diagnostic Use of Liposomes and Carbon Nanomaterials in Ischemic Stroke

(2018) Lorena F. Fernandes et al.   Frontiers in Neuroscience

Thrombin-Responsive, Brain-Targeting Nanoparticles for Improved Stroke Therapy

(2018) Xing Guo et al.   ACS Nano

Bioresponsive Nanoparticles Targeted to Infectious Microenvironments for Sepsis Management

(2018) Can Yang Zhang et al.   ADVANCED MATERIALS

Damage-Associated Molecular Patterns in Inflammatory Diseases

(2018) Jong Seong Roh et al.   Immune Network

Combination therapy with liposomal neuroprotectants and tissue plasminogen activator for treatment of ischemic stroke

(2017) Tatsuya Fukuta et al.   FASEB JOURNAL

Cell membrane-derived nanoparticles: emerging clinical opportunities for targeted drug delivery

(2017) Svetlana T Yurkin et al.   Nanomedicine

Leukocyte-mediated Delivery of Nanotherapeutics in Inflammatory and Tumor Sites

(2017) Xinyue Dong et al.   Theranostics

Stroke Management: An Emerging Role of Nanotechnology

(2017) Deepaneeta Sarmah et al.   Micromachines

The blood–brain barrier after stroke: Structural studies and the role of transcytotic vesicles

(2016) Michael J Haley et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cell membrane-formed nanovesicles for disease-targeted delivery

(2016) Jin Gao et al.   JOURNAL OF CONTROLLED RELEASE

Dual targeted nanocarrier for brain ischemic stroke treatment

(2016) Yue Zhao et al.   JOURNAL OF CONTROLLED RELEASE

Intranasal delivery of bFGF with nanoliposomes enhances in vivo neuroprotection and neural injury recovery in a rodent stroke model

(2016) Ying-Zheng Zhao et al.   JOURNAL OF CONTROLLED RELEASE

Inflammation and Stroke: An Overview

(2016) Josef Anrather et al.   Neurotherapeutics

The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults

(2016) Małgorzata Nita et al.   Oxidative Medicine and Cellular Longevity

High-Performance Upconversion Nanoprobes for Multimodal MR Imaging of Acute Ischemic Stroke

(2016) Jing Wang et al.   Small

Imaging Nanotherapeutics in Inflamed Vasculature by Intravital Microscopy

(2016) Zhenjia Wang   Theranostics

Nanoparticle Targeting of Neutrophils for Improved Cancer Immunotherapy

(2016) Dafeng Chu et al.   Advanced Healthcare Materials

Neutrophil-Mediated Delivery of Therapeutic Nanoparticles across Blood Vessel Barrier for Treatment of Inflammation and Infection

(2015) Dafeng Chu et al.   ACS Nano

Nanoparticles in magnetic resonance imaging: from simple to dual contrast agents

(2015) M. Antonia Busquets et al.   International Journal of Nanomedicine

A holistic approach to targeting disease with polymeric nanoparticles

(2015) Christopher J. Cheng et al.   NATURE REVIEWS DRUG DISCOVERY

Enhanced anti-ischemic stroke of ZL006 by T7-conjugated PEGylated liposomes drug delivery system

(2015) Zhongyuan Wang et al.   Scientific Reports

Therapeutic benefits of nanoparticles in stroke

(2015) Stavros Panagiotou et al.   Frontiers in Neuroscience

Advances and Challenges of Liposome Assisted Drug Delivery

(2015) Lisa Sercombe et al.   Frontiers in Pharmacology

Reperfusion injury and reactive oxygen species: The evolution of a concept

(2015) D. Neil Granger et al.   Redox Biology

In vivo monitoring of neural stem cells after transplantation in acute cerebral infarction with dual-modal MR imaging and optical imaging

(2014) Xuehua Wen et al.   BIOMATERIALS

Pattern recognition receptors and central nervous system repair

(2014) Kristina A. Kigerl et al.   EXPERIMENTAL NEUROLOGY

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Prevention of vascular inflammation by nanoparticle targeting of adherent neutrophils

(2014) Zhenjia Wang et al.   Nature Nanotechnology

Stepwise Recruitment of Transcellular and Paracellular Pathways Underlies Blood-Brain Barrier Breakdown in Stroke

(2014) Daniel Knowland et al.   NEURON

The impact of microglial activation on blood-brain barrier in brain diseases

(2014) Anna Carolina Carvalho da Fonseca et al.   Frontiers in Cellular Neuroscience

In Vivo Theranostics at the Peri-Infarct Region in Cerebral Ischemia

(2014) Jesús Agulla et al.   Theranostics

Nanotechnology for the Detection and Therapy of Stroke

(2014) Stuart Kyle et al.   Advanced Healthcare Materials

Reperfusion Therapies of Acute Ischemic Stroke: Potentials and Failures

(2014) Georgios Tsivgoulis et al.   Frontiers in Neurology

Reactive Oxygen Species in Inflammation and Tissue Injury

(2013) Manish Mittal et al.   ANTIOXIDANTS & REDOX SIGNALING

The effect of cationic albumin-conjugated PEGylated tanshinone IIA nanoparticles on neuronal signal pathways and neuroprotection in cerebral ischemia

(2013) Xin Liu et al.   BIOMATERIALS

Targeted therapy of brain ischaemia using Fas ligand antibody conjugated PEG-lipid nanoparticles

(2013) Ying-mei Lu et al.   BIOMATERIALS

Selective Neuronal Loss in Ischemic Stroke and Cerebrovascular Disease

(2013) Jean-Claude Baron et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Strategies for advancing cancer nanomedicine

(2013) Vikash P. Chauhan et al.   NATURE MATERIALS

Nanomaterials in Stroke Treatment: Perspectives

(2013) N. Shcharbina et al.   STROKE

Ceria Nanoparticles that can Protect against Ischemic Stroke

(2012) Chi Kyung Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protective effects of cationic bovine serum albumin-conjugated PEGylated tanshinone IIA nanoparticles on cerebral ischemia

(2012) Xin Liu et al.   BIOMATERIALS

Neuroprotection for Stroke: Current Status and Future Perspectives

(2012) Jens Minnerup et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pathophysiologic Cascades in Ischemic Stroke

(2012) Changhong Xing et al.   International Journal of Stroke

Amelioration of cerebral ischemia–reperfusion injury based on liposomal drug delivery system with asialo-erythropoietin

(2012) Takayuki Ishii et al.   JOURNAL OF CONTROLLED RELEASE

Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis

(2012) Baptiste N. Jaeger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The immunology of acute stroke

(2012) Ángel Chamorro et al.   Nature Reviews Neurology

Strong neuroprotection with a novel platinum nanoparticle against ischemic stroke- and tissue plasminogen activator-related brain damages in mice

(2012) M. Takamiya et al.   NEUROSCIENCE

Delivery of nanoparticle-complexed drugs across the vascular endothelial barrier via caveolae

(2011) Zhenjia Wang et al.   IUBMB LIFE

Dexamethasone-loaded peptide micelles for delivery of the heme oxygenase-1 gene to ischemic brain

(2011) Jiyoung Lee et al.   JOURNAL OF CONTROLLED RELEASE

Neurological and pathological improvements of cerebral infarction in mice with platinum nanoparticles

(2011) Motonori Takamiya et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Functional motor recovery from brain ischemic insult by carbon nanotube-mediated siRNA silencing

(2011) K. T. Al-Jamal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood–Brain Barrier Breakdown in Acute and Chronic Cerebrovascular Disease

(2011) Yi Yang et al.   STROKE

Anti-inflammatory Agents: Present and Future

(2010) Charles A. Dinarello   CELL

Matrix Metalloproteinase-9 Mediates Hypoxia-Induced Vascular Leakage in the Brain via Tight Junction Rearrangement

(2010) Alexander T Bauer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

(2010) Rong Jin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95

(2010) Li Zhou et al.   NATURE MEDICINE

Size and Dynamics of Caveolae Studied Using Nanoparticles in Living Endothelial Cells

(2009) Zhenjia Wang et al.   ACS Nano

Adenosine and Stroke: Maximizing the Therapeutic Potential of Adenosine as a Prophylactic and Acute Neuroprotectant

(2009) Rebecca Williams-Karnesky et al.   Current Neuropharmacology

Neuroprotection by biodegradable PAMAM ester (e-PAM-R)-mediated HMGB1 siRNA delivery in primary cortical cultures and in the postischemic brain

(2009) Il-Doo Kim et al.   JOURNAL OF CONTROLLED RELEASE

A Nanomedicine Transports a Peptide Caspase-3 Inhibitor across the Blood-Brain Barrier and Provides Neuroprotection

(2009) H. Karatas et al.   JOURNAL OF NEUROSCIENCE

In vitrofree radical scavenging activity of platinum nanoparticles

(2009) Aki Watanabe et al.   NANOTECHNOLOGY

Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis

(2009) Matthew Spite et al.   NATURE

Role of oxidative stress and nitric oxide in atherothrombosis

(2008) Edith Lubos   Frontiers in Bioscience-Landmark

Neuroprotection for ischemic stroke: Past, present and future

(2008) Myron D. Ginsberg   NEUROPHARMACOLOGY

NXY-059 for the Treatment of Acute Stroke

(2008) Hans-Christoph Diener et al.   STROKE