Altered Ovarian Inositol Ratios May Account for Pathological Steroidogenesis in PCOS

Experts’ opinion on Inositols in treating polycystic ovary syndrome and non-insulin dependent diabetes mellitus: a further help for human reproduction and beyond

(2020) Fabio Facchinetti et al.   Expert Opinion on Drug Metabolism & Toxicology

Inositols in Polycystic Ovary Syndrome: An Overview on the Advances

(2020) Fabio Facchinetti et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Short-term effects of metformin and myo-inositol in women with polycystic ovarian syndrome (PCOS): a meta-analysis of randomized clinical trials

(2019) Fabio Facchinetti et al.   GYNECOLOGICAL ENDOCRINOLOGY

Do inositol supplements enhance phosphatidylinositol supply and thus support endoplasmic reticulum function?

(2018) Robert H. Michell   BRITISH JOURNAL OF NUTRITION

Effects of myo-inositol plus alpha-lactalbumin in myo-inositol-resistant PCOS women

(2018) Mario Montanino Oliva et al.   Journal of Ovarian Research

Alpha-lactalbumin effect on myo-inositol intestinal absorption: in vivo and in vitro

(2018) Giovanni Monastra et al.   Current Drug Delivery

Inositol in Polycystic Ovary Syndrome: Restoring Fertility through a Pathophysiology-Based Approach

(2018) Antonio Simone Laganà et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Myo-inositol and D-chiro-inositol (40:1) reverse histological and functional features of polycystic ovary syndrome in a mouse model

(2018) Arturo Bevilacqua et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inositols in Insulin Signaling and Glucose Metabolism

(2018) Arturo Bevilacqua et al.   International Journal of Endocrinology

Insulin resistance in a large cohort of women with polycystic ovary syndrome: a comparison between euglycaemic-hyperinsulinaemic clamp and surrogate indexes

(2017) Flavia Tosi et al.   HUMAN REPRODUCTION

Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials

(2017) Vittorio Unfer et al.   Endocrine Connections

Pharmacodynamics and pharmacokinetics of inositol(s) in health and disease

(2016) Mariano Bizzarri et al.   Expert Opinion on Drug Metabolism & Toxicology

Inositol and human reproduction. From cellular metabolism to clinical use

(2016) Ewa M. Milewska et al.   GYNECOLOGICAL ENDOCRINOLOGY

Combining treatment with myo-inositol andD-chiro-inositol (40:1) is effective in restoring ovary function and metabolic balance in PCOS patients

(2016) Giovanni Monastra et al.   GYNECOLOGICAL ENDOCRINOLOGY

Myo-inositol inhibits intestinal glucose absorption and promotes muscle glucose uptake: a dual approach study

(2016) Chika Ifeanyi Chukwuma et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Modulation of gonadotrophin induced steroidogenic enzymes in granulosa cells by d-chiroinositol

(2016) Sandro Sacchi et al.   Reproductive Biology and Endocrinology

A Combined Therapy with Myo-Inositol and D-Chiro-Inositol Improves Endocrine Parameters and Insulin Resistance in PCOS Young Overweight Women

(2016) Elena Benelli et al.   International Journal of Endocrinology

Myo-Inositol in the Treatment of Teenagers Affected by PCOS

(2016) Lali Pkhaladze et al.   International Journal of Endocrinology

Reflections on inositol(s) for PCOS therapy: steps toward success

(2015) John E. Nestler et al.   GYNECOLOGICAL ENDOCRINOLOGY

Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance

(2014) Zdravko Kamenov et al.   GYNECOLOGICAL ENDOCRINOLOGY

Phytic acid and myo-inositol support adipocyte differentiation and improve insulin sensitivity in 3T3-L1 cells

(2014) Jin Nam Kim et al.   NUTRITION RESEARCH

Hyperinsulinemia Alters Myoinositol to d-chiroinositol Ratio in the Follicular Fluid of Patients With PCOS

(2014) Vittorio Unfer et al.   Reproductive Sciences

Potential role and therapeutic interests of myo-inositol in metabolic diseases

(2013) Marine L. Croze et al.   BIOCHIMIE

Decreased myo-inositol to chiro-inositol (M/C) ratios and increased M/C epimerase activity in PCOS theca cells demonstrate increased insulin sensitivity compared to controls

(2013) Douglas Heimark et al.   ENDOCRINE JOURNAL

Endocrine and clinical effects of myo-inositol administration in polycystic ovary syndrome. A randomized study

(2013) P. G. Artini et al.   GYNECOLOGICAL ENDOCRINOLOGY

Comparison between effects of myo-inositol andd-chiro-inositol on ovarian function and metabolic factors in women with PCOS

(2013) Alfonsa Pizzo et al.   GYNECOLOGICAL ENDOCRINOLOGY

Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications

(2012) Evanthia Diamanti-Kandarakis et al.   ENDOCRINE REVIEWS

Effects of myo-inositol in women with PCOS: a systematic review of randomized controlled trials

(2012) V. Unfer et al.   GYNECOLOGICAL ENDOCRINOLOGY

The D-chiro-inositol paradox in the ovary

(2011) Gianfranco Carlomagno et al.   FERTILITY AND STERILITY

Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan

(2010) H Teede et al.   BMC Medicine

Insulin sensitiser agents alone and in co-treatment with r-FSH for ovulation induction in PCOS women

(2009) Emanuela Raffone et al.   GYNECOLOGICAL ENDOCRINOLOGY

The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report

(2008) Ricardo Azziz et al.   FERTILITY AND STERILITY

Myo-inositol administration positively affects hyperinsulinemia and hormonal parameters in overweight patients with polycystic ovary syndrome

(2008) Alessandro D. Genazzani et al.   GYNECOLOGICAL ENDOCRINOLOGY

Insulin-stimulated release of d-chiro-inositol–containing inositolphosphoglycan mediator correlates with insulin sensitivity in women with polycystic ovary syndrome

(2008) Kai I. Cheang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL