Aryl Hydrocarbon Receptor (AHR) Ligands as Selective AHR Modulators (SAhRMs)
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Title
Aryl Hydrocarbon Receptor (AHR) Ligands as Selective AHR Modulators (SAhRMs)
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 18, Pages 6654
Publisher
MDPI AG
Online
2020-09-11
DOI
10.3390/ijms21186654
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Note: Only part of the references are listed.- The Ah Receptor: Adaptive Metabolism, Ligand Diversity, and the Xenokine Model
- (2020) Mele N. Avilla et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Leveraging Nuclear Receptors as Targets for Pathological Ocular Vascular Diseases
- (2020) Pei-Li Yao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ah receptor ligands and their impacts on gut resilience: structure–activity effects
- (2020) Stephen Safe et al. CRITICAL REVIEWS IN TOXICOLOGY
- Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway
- (2019) Rajbir Singh et al. Nature Communications
- Malassezia Is Associated with Crohn’s Disease and Exacerbates Colitis in Mouse Models
- (2019) Jose J. Limon et al. Cell Host & Microbe
- Ablation of aryl hydrocarbon receptor promotes angiotensin II-induced cardiac fibrosis through enhanced c-Jun/HIF-1α signaling
- (2019) Sahoko Ichihara et al. ARCHIVES OF TOXICOLOGY
- Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogenesis in Mice
- (2019) Jiong Yan et al. GASTROENTEROLOGY
- The aryl hydrocarbon receptor is a tumor suppressor–like gene in glioblastoma
- (2019) Un-Ho Jin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metabolites in a Mouse Cancer Model Enhance Venous Thrombogenicity Through Aryl Hydrocarbon Receptor-Tissue Factor Axis
- (2019) Mostafa Belghasem et al. BLOOD
- Aryl hydrocarbon receptor modulates stroke-induced astrogliosis and neurogenesis in the adult mouse brain
- (2019) Wan-Ci Chen et al. Journal of Neuroinflammation
- Aryl Hydrocarbon Receptor Contributes to the Transcriptional Program of IL-10-Producing Regulatory B Cells
- (2019) Christopher J.M. Piper et al. Cell Reports
- Targeting Aryl hydrocarbon receptor for next-generation immunotherapies: Selective modulators (SAhRMs) versus rapidly metabolized ligands (RMAhRLs)
- (2019) Daniela Dolciami et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Suppression of aberrant choroidal neovascularization through activation of the aryl hydrocarbon receptor
- (2018) Mayur Choudhary et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses
- (2018) Shankar S. Iyer et al. CELL
- Regulation of the Immune Response by the Aryl Hydrocarbon Receptor
- (2018) Cristina Gutiérrez-Vázquez et al. IMMUNITY
- Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity
- (2018) Min Yu et al. International Journal of Biological Sciences
- The role of aryl hydrocarbon receptor in bone remodeling
- (2018) Haitao Yu et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Structure-Dependent Modulation of Aryl Hydrocarbon Receptor-Mediated Activities by Flavonoids
- (2018) Un-Ho Jin et al. TOXICOLOGICAL SCIENCES
- 2,3,7,8-Tetrachlorodibenzo- p -dioxin dose-dependently increases bone mass and decreases marrow adiposity in juvenile mice
- (2018) Kelly A. Fader et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Serotonin is an endogenous regulator of intestinal CYP1A1 via AhR
- (2018) Christopher Manzella et al. Scientific Reports
- Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages
- (2018) Smitha Krishnan et al. Cell Reports
- Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway
- (2018) Kai Wang et al. BIOCHEMICAL PHARMACOLOGY
- The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity
- (2018) Amina Metidji et al. IMMUNITY
- Dietary tryptophan alleviates dextran sodium sulfate-induced colitis through aryl hydrocarbon receptor in mice
- (2017) Jahidul Islam et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Inhibition of acute lethal pulmonary inflammation by the IDO–AhR pathway
- (2017) Soung-Min Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T cells that restrain asthmatic responses
- (2017) Sofia Tousa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dietary broccoli impacts microbial community structure and attenuates chemically induced colitis in mice in an Ah receptor dependent manner
- (2017) Troy D. Hubbard et al. Journal of Functional Foods
- The Aryl Hydrocarbon Receptor Preferentially Marks and Promotes Gut Regulatory T Cells
- (2017) Jian Ye et al. Cell Reports
- AhR-deficiency as a cause of demyelinating disease and inflammation
- (2017) Ludmila Juricek et al. Scientific Reports
- The Aryl Hydrocarbon Receptor is a Repressor of Inflammation-associated Colorectal Tumorigenesis in Mouse
- (2016) Carol J. Díaz-Díaz et al. ANNALS OF SURGERY
- Indigo Naturalis ameliorates murine dextran sodium sulfate-induced colitis via aryl hydrocarbon receptor activation
- (2016) Shoichiro Kawai et al. JOURNAL OF GASTROENTEROLOGY
- The Nuclear Receptor AhR Controls Bone Homeostasis by Regulating Osteoclast Differentiation via the RANK/c-Fos Signaling Axis
- (2016) Takashi Izawa et al. JOURNAL OF IMMUNOLOGY
- Aryl Hydrocarbon Receptor in Keratinocytes Is Essential for Murine Skin Barrier Integrity
- (2016) Katharina Haas et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- A comprehensive map of molecular drug targets
- (2016) Rita Santos et al. NATURE REVIEWS DRUG DISCOVERY
- AhR signaling activation disrupts migration and dendritic growth of olfactory interneurons in the developing mouse
- (2016) Eiki Kimura et al. Scientific Reports
- AHR Activation Is Protective against Colitis Driven by T Cells in Humanized Mice
- (2016) Jeremy A. Goettel et al. Cell Reports
- Blocking peripheral serotonin synthesis by telotristat etiprate (LX1032/LX1606) reduces severity of both chemical- and infection-induced intestinal inflammation
- (2015) Janice J. Kim et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Extranuclear Steroid Receptors Are Essential for Steroid Hormone Actions
- (2015) Ellis R. Levin Annual Review of Medicine
- Pityriazepin and other potent AhR ligands isolated from Malassezia furfur yeast
- (2015) Nikitia Mexia et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Omeprazole Inhibits Pancreatic Cancer Cell Invasion through a Nongenomic Aryl Hydrocarbon Receptor Pathway
- (2015) Un-Ho Jin et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Aryl hydrocarbon receptor deletion in cerebellar granule neuron precursors impairs neurogenesis
- (2015) Daniel P. Dever et al. Developmental Neurobiology
- Aryl Hydrocarbon Receptor Activation Down-Regulates IL-7 and Reduces Inflammation in a Mouse Model of DSS-Induced Colitis
- (2015) Tao Ji et al. DIGESTIVE DISEASES AND SCIENCES
- Norisoboldine ameliorates DSS-induced ulcerative colitis in mice through induction of regulatory T cells in colons
- (2015) Qi Lv et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Celebrating 75 years of oestradiol
- (2015) Evan Simpson et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Ah receptor pathway intricacies; signaling through diverse protein partners and DNA-motifs
- (2015) D. P. Jackson et al. Toxicology Research
- The Aryl Hydrocarbon Receptor: Multitasking in the Immune System
- (2014) Brigitta Stockinger et al. Annual Review of Immunology
- Aryl hydrocarbon receptor catabolic activity in bone metabolism is osteoclast dependent in vivo
- (2014) Tai-yong Yu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- L-Kynurenine/Aryl Hydrocarbon Receptor Pathway Mediates Brain Damage After Experimental Stroke
- (2014) María I. Cuartero et al. CIRCULATION
- Activation of the Aryl Hydrocarbon Receptor Dampens the Severity of Inflammatory Skin Conditions
- (2014) Paola Di Meglio et al. IMMUNITY
- Identification of a probiotic bacteria-derived activator of the aryl hydrocarbon receptor that inhibits colitis
- (2014) Suguru Fukumoto et al. IMMUNOLOGY AND CELL BIOLOGY
- Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22
- (2013) Teresa Zelante et al. IMMUNITY
- The Ah receptor regulates growth factor expression in head and neck squamous cell carcinoma cell lines
- (2013) Kaarthik John et al. MOLECULAR CARCINOGENESIS
- Oculomotor Deficits in Aryl Hydrocarbon Receptor Null Mouse
- (2013) Aline Chevallier et al. PLoS One
- Polybrominated Dibenzo-p-Dioxins, Dibenzofurans, and Biphenyls: Inclusion in the Toxicity Equivalency Factor Concept for Dioxin-Like Compounds
- (2013) Martin van den Berg et al. TOXICOLOGICAL SCIENCES
- New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties
- (2013) Maria Herlin et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- The Aryl Hydrocarbon Receptor Complex and the Control of Gene Expression
- (2012) Timothy V. Beischlag et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- Deletion or activation of the aryl hydrocarbon receptor alters adult hippocampal neurogenesis and contextual fear memory
- (2012) Sarah E. Latchney et al. JOURNAL OF NEUROCHEMISTRY
- Ah Receptor Antagonism Represses Head and Neck Tumor Cell Aggressive Phenotype
- (2012) B. C. DiNatale et al. MOLECULAR CANCER RESEARCH
- Uric acid stones in the urinary bladder of aryl hydrocarbon receptor (AhR) knockout mice
- (2012) R. Butler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of the Ah-Receptor Structural Determinants for Ligand Preferences
- (2012) Yongna Xing et al. TOXICOLOGICAL SCIENCES
- Activation of the Aryl Hydrocarbon Receptor During Pregnancy in the Mouse Alters Mammary Development Through Direct Effects on Stromal and Epithelial Tissues1
- (2011) Betina J. Lew et al. BIOLOGY OF REPRODUCTION
- Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation
- (2011) Ying Li et al. CELL
- A Role of the Aryl Hydrocarbon Receptor in Attenuation of Colitis
- (2011) Keisuke Furumatsu et al. DIGESTIVE DISEASES AND SCIENCES
- An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
- (2011) Christiane A. Opitz et al. NATURE
- Activation of Aryl Hydrocarbon Receptor (AhR) Leads to Reciprocal Epigenetic Regulation of FoxP3 and IL-17 Expression and Amelioration of Experimental Colitis
- (2011) Narendra P. Singh et al. PLoS One
- Dioxin and immune regulation
- (2010) Nikki B. Marshall et al. Annals of the New York Academy of Sciences
- Transcriptional Factor Aryl Hydrocarbon Receptor (Ahr) Controls Cardiovascular and Respiratory Functions by Regulating the Expression of theVav3Proto-oncogene
- (2010) Vincent Sauzeau et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ah receptor antagonism inhibits constitutive and cytokine inducible IL6 production in head and neck tumor cell lines
- (2010) Brett C. DiNatale et al. MOLECULAR CARCINOGENESIS
- Aryl Hydrocarbon Receptor-Null Allele Mice Have Hematopoietic Stem/Progenitor Cells with Abnormal Characteristics and Functions
- (2010) Kameshwar P. Singh et al. STEM CELLS AND DEVELOPMENT
- Dioxin Exposure Disrupts the Differentiation of Mouse Embryonic Stem Cells into Cardiomyocytes
- (2010) Ying Wang et al. TOXICOLOGICAL SCIENCES
- Differential Gene Regulation by the Human and Mouse Aryl Hydrocarbon Receptor
- (2010) Colin A. Flaveny et al. TOXICOLOGICAL SCIENCES
- Automated Dose-Response Analysis and Comparative Toxicogenomic Evaluation of the Hepatic Effects Elicited by TCDD, TCDF, and PCB126 in C57BL/6 Mice
- (2010) Anna K. Kopec et al. TOXICOLOGICAL SCIENCES
- Aryl Hydrocarbon Receptor Activation by TCDD Reduces Inflammation Associated with Crohn's Disease
- (2010) Jenna M. Benson et al. TOXICOLOGICAL SCIENCES
- Knockdown of the aryl hydrocarbon receptor attenuates excitotoxicity and enhances NMDA-induced BDNF expression in cortical neurons
- (2009) Chun-Hua Lin et al. JOURNAL OF NEUROCHEMISTRY
- Ligand Selectivity and Gene Regulation by the Human Aryl Hydrocarbon Receptor in Transgenic Mice
- (2009) C. A. Flaveny et al. MOLECULAR PHARMACOLOGY
- Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands
- (2009) K. Kawajiri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Automated Dose-Response Analysis of the Relative Hepatic Gene Expression Potency of TCDF in C57BL/6 Mice
- (2009) Lyle D. Burgoon et al. TOXICOLOGICAL SCIENCES
- Leukotriene A4Metabolites Are Endogenous Ligands for the Ah Receptor†
- (2008) Christopher R. Chiaro et al. BIOCHEMISTRY
- Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways
- (2008) Stephen Safe et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
- (2008) Marc Veldhoen et al. NATURE
- Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor
- (2008) Francisco J. Quintana et al. NATURE
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