Elucidation of Melanogenesis Cascade for Identifying Pathophysiology and Therapeutic Approach of Pigmentary Disorders and Melanoma

Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells

(2020) Bing Zhang et al.   NATURE

BLOC1S5 pathogenic variants cause a new type of Hermansky–Pudlak syndrome

(2020) Perrine Pennamen et al.   GENETICS IN MEDICINE

Human melanocortin 1 receptor-mediated ubiquitination of nonvisual arrestins. Role of Mahogunin Ring Finger 1 E3 ligase

(2018) Marta Abrisqueta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Targeting prohibitin with small molecules to promote melanogenesis and apoptosis in melanoma cells

(2018) Amel Djehal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology

(2017) Akinori Kawakami et al.   LABORATORY INVESTIGATION

A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin

(2017) Nisma Mujahid et al.   Cell Reports

Current treatments for advanced melanoma and introduction of a promising novel gene therapy for melanoma (Review)

(2016) Jae-Rim Heo et al.   ONCOLOGY REPORTS

Microtubule-associated protein light chain 3 is involved in melanogenesis via regulation of MITF expression in melanocytes

(2016) Woo Jin Yun et al.   Scientific Reports

Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up

(2015) Fan Liu et al.   HUMAN GENETICS

Antitumor immunity by magnetic nanoparticle-mediated hyperthermia

(2014) Takeshi Kobayashi et al.   Nanomedicine

MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation

(2014) Jose C. García-Borrón et al.   Pigment Cell & Melanoma Research

Mahogunin-mediated α-tubulin ubiquitination via noncanonical K6 linkage regulates microtubule stability and mitotic spindle orientation

(2014) D Srivastava et al.   Cell Death & Disease

Melanocytes and Their Diseases

(2014) Y. Yamaguchi et al.   Cold Spring Harbor Perspectives in Medicine

Molecular and Functional Analysis of Human β-Defensin 3 Action at Melanocortin Receptors

(2013) Matthew A. Nix et al.   CHEMISTRY & BIOLOGY

N-propionyl-4-S-cysteaminylphenol induces apoptosis in B16F1 cells and mediates tumor-specific T-cell immune responses in a mouse melanoma model

(2012) Yasue Ishii-Osai et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Defining MC1R Regulation in Human Melanocytes by Its Agonist α-Melanocortin and Antagonists Agouti Signaling Protein and β-Defensin 3

(2012) Viki B. Swope et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

T-cell receptor repertoires of tumor-infiltrating lymphocytes after hyperthermia using functionalized magnetite nanoparticles

(2012) Akira Ito et al.   Nanomedicine

Mechanisms of Protein Delivery to Melanosomes in Pigment Cells

(2012) Anand Sitaram et al.   PHYSIOLOGY

MGRN1-dependent pigment-type switching requires its ubiquitination activity but not its interaction with TSG101 or NEDD4

(2012) Teresa M. Gunn et al.   Pigment Cell & Melanoma Research

Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest

(2011) I. Adameyko et al.   DEVELOPMENT

Proprotein Convertases Process Pmel17 during Secretion

(2011) Ralf M. Leonhardt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Key Discoveries in Melanocyte Development

(2011) Akinori Kawakami et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

La biogenèse des mélanosomes

(2011) Cédric Delevoye et al.   M S-MEDECINE SCIENCES

Melanoma-targeted chemo-thermo-immuno (CTI)-therapy using N-propionyl-4-S-cysteaminylphenol-magnetite nanoparticles elicits CTL response via heat shock protein-peptide complex release

(2010) Akiko Sato et al.   CANCER SCIENCE

Rab7 is a critical mediator in vesicular transport of tyrosinase-related protein 1 in melanocytes

(2010) Tokimasa HIDA et al.   JOURNAL OF DERMATOLOGY

Schwann Cell Precursors from Nerve Innervation Are a Cellular Origin of Melanocytes in Skin

(2009) Igor Adameyko et al.   CELL

Genotoxic Stress Abrogates Renewal of Melanocyte Stem Cells by Triggering Their Differentiation

(2009) Ken Inomata et al.   CELL

The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition

(2009) Francesca Giordano et al.   HUMAN MOLECULAR GENETICS

Mahogunin Ring Finger-1 (MGRN1) E3 Ubiquitin Ligase Inhibits Signaling from Melanocortin Receptor by Competition with Gαs

(2009) Ana B. Pérez-Oliva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Growth Inhibition of Re-Challenge B16 Melanoma Transplant by Conjugates of Melanogenesis Substrate and Magnetite Nanoparticles as the Basis for Developing Melanoma-Targeted Chemo-Thermo-Immunotherapy

(2009) Tomoaki Takada et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

N-Propionyl-Cysteaminylphenol-Magnetite Conjugate (NPrCAP/M) Is a Nanoparticle for the Targeted Growth Suppression of Melanoma Cells

(2009) Makito Sato et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway

(2009) Tokimasa Hida et al.   Pigment Cell & Melanoma Research

Current challenges in understanding melanogenesis: bridging chemistry, biological control, morphology, and function

(2009) John D Simon et al.   Pigment Cell & Melanoma Research

Microphthalmia-associated Transcription Factor RegulatesRAB27AGene Expression and Controls Melanosome Transport

(2008) Christine Chiaverini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two newly identified genetic determinants of pigmentation in Europeans

(2008) Patrick Sulem et al.   NATURE GENETICS

L-DOPA Is an Endogenous Ligand for OA1

(2008) Vanessa M Lopez et al.   PLOS BIOLOGY

Rab7 Regulates Maturation of Melanosomal Matrix Protein gp100/Pmel17/Silv

(2007) Akinori Kawakami et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Chemistry of Mixed Melanogenesis—Pivotal Roles of Dopaquinone

(2007) Shosuke Ito et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY