MDM2 inhibition improves cisplatin-induced renal injury in mice via inactivation of Notch/hes1 signaling pathway

γ-secretase inhibitor DAPT mitigates cisplatin-induced acute kidney injury by suppressing Notch1 signaling

(2018) Hitesh Soni et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Dexmedetomidine protects against cisplatin-induced acute kidney injury in mice through regulating apoptosis and inflammation

(2017) H. Liang et al.   INFLAMMATION RESEARCH

MDM2 is implicated in high-glucose-induced podocyte mitotic catastrophe via Notch1 signalling

(2017) Hui Tang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cisplatin nephrotoxicity: a review of the literature

(2017) Sandhya Manohar et al.   JOURNAL OF NEPHROLOGY

MiR-30c regulates cisplatin-induced apoptosis of renal tubular epithelial cells by targeting Bnip3L and Hspa5

(2017) Bin Du et al.   Cell Death & Disease

MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1

(2017) Chun-Tao Lei et al.   Scientific Reports

Nephrotoxicity of cisplatin combination chemotherapy in thoracic malignancy patients with CKD risk factors

(2016) Ko Sato et al.   BMC CANCER

MDM2 prevents spontaneous tubular epithelial cell death and acute kidney injury

(2016) Dana Thomasova et al.   Cell Death & Disease

Serum cystatin C and microalbuminuria in burn patients with acute kidney injury

(2015) Haejun Yim et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

The liver X receptor agonist TO901317 protects mice against cisplatin-induced kidney injury

(2015) Meng Yang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Renoprotective effects of angiotensin receptor blocker and stem cells in acute kidney injury: Involvement of inflammatory and apoptotic markers

(2015) Iman O Sherif et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

An integrated view of cisplatin-induced nephrotoxicity and ototoxicity

(2015) Takatoshi Karasawa et al.   TOXICOLOGY LETTERS

Monocyte Caspase-1 Is Released in a Stable, Active High Molecular Weight Complex Distinct from the Unstable Cell Lysate-Activated Caspase-1

(2015) Obada R. Shamaa et al.   PLoS One

Non-degradative ubiquitination of the Notch1 receptor by the E3 ligase MDM2 activates the Notch signalling pathway

(2013) Susanne Pettersson et al.   BIOCHEMICAL JOURNAL

ERK-mediated suppression of cilia in cisplatin-induced tubular cell apoptosis and acute kidney injury

(2013) Shixuan Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Aberrant Notch1-dependent effects on glomerular parietal epithelial cells promotes collapsing focal segmental glomerulosclerosis with progressive podocyte loss

(2013) Toshiharu Ueno et al.   KIDNEY INTERNATIONAL

5-Aminolevulinic Acid Protects against Cisplatin-Induced Nephrotoxicity without Compromising the Anticancer Efficiency of Cisplatin in Rats In Vitro and In Vivo

(2013) Yoshio Terada et al.   PLoS One

DAP5 Ameliorates Cisplatin-Induced Apoptosis of Renal Tubular Cells

(2012) Jian-jun Gao et al.   AMERICAN JOURNAL OF NEPHROLOGY

Cisplatin-induced nephrotoxicity and targets of nephroprotection: an update

(2012) Neife Aparecida Guinaim dos Santos et al.   ARCHIVES OF TOXICOLOGY

MDM2 Protein-mediated Ubiquitination of NUMB Protein

(2012) Matylda Sczaniecka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MDM2 (murine double minute-2) links inflammation and tubular cell healing during acute kidney injury in mice

(2012) Shrikant R. Mulay et al.   KIDNEY INTERNATIONAL

Notch signaling pathway regulates proliferation and differentiation of immortalized Müller cells under hypoxic conditions in vitro

(2012) Z. Wang et al.   NEUROSCIENCE

C-Phycocyanin Attenuates Cisplatin-Induced Nephrotoxicity in Mice

(2012) Beom Jin Lim et al.   RENAL FAILURE

hCLP46 regulates U937 cell proliferation via Notch signaling pathway

(2011) Wenzhan Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

An Mdm2 antagonist, Nutlin-3a, induces p53-dependent and proteasome-mediated poly(ADP-ribose) polymerase1 degradation in mouse fibroblasts

(2011) Shingo Matsushima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

cAMP signalling protects proximal tubular epithelial cells from cisplatin-induced apoptosis via activation of Epac

(2011) Yu Qin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cellular pathophysiology of ischemic acute kidney injury

(2011) Joseph V. Bonventre et al.   JOURNAL OF CLINICAL INVESTIGATION

Notch2/Hes-1 Pathway Plays an Important Role in Renal Ischemia and Reperfusion Injury-Associated Inflammation and Apoptosis and the γ-Secretase Inhibitor DAPT has a Nephroprotective Effect

(2011) RenFa Huang et al.   RENAL FAILURE

Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects

(2011) Ana-Maria Florea et al.   Cancers

Luteolin ameliorates cisplatin-induced acute kidney injury in mice by regulation of p53-dependent renal tubular apoptosis

(2010) Kyung Pyo Kang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Interleukin-6 deficiency accelerates cisplatin-induced acute renal failure but not systemic injury

(2009) S. Mitazaki et al.   TOXICOLOGY

Neutrophil Gelatinase–Associated Lipocalin (NGAL) as a Marker of Kidney Damage

(2008) Davide Bolignano et al.   AMERICAN JOURNAL OF KIDNEY DISEASES