Clinical and psychological outcomes of receiving a variant of uncertain significance from multigene panel testing or genomic sequencing: a systematic review and meta-analysis

NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 1.2020

(2020) Mary B. Daly et al.   Journal of the National Comprehensive Cancer Network

The Responsibility to Recontact Research Participants after Reinterpretation of Genetic and Genomic Research Results

(2019) Yvonne Bombard et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Variant classification changes over time in BRCA1 and BRCA2

(2019) Chloe Mighton et al.   GENETICS IN MEDICINE

Psychological outcomes related to exome and genome sequencing result disclosure: a meta-analysis of seven Clinical Sequencing Exploratory Research (CSER) Consortium studies

(2019) Jill O. Robinson et al.   GENETICS IN MEDICINE

Disclosure of cardiac variants of uncertain significance results in an exome cohort

(2018) T.A. Lawal et al.   CLINICAL GENETICS

Impact of Multigene Panel Testing on Surgical Decision Making in Breast Cancer Patients

(2018) Holly J. Pederson et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Factors influencing the decision to share cancer genetic results among family members: An in-depth interview study of women in an Asian setting

(2018) Shao-Tzu Li et al.   PSYCHO-ONCOLOGY

Psychological impact of multigene cancer panel testing in patients with a clinical suspicion of hereditary cancer across Spain

(2018) I. Esteban et al.   PSYCHO-ONCOLOGY

Prevalence of Variant Reclassification Following Hereditary Cancer Genetic Testing

(2018) Jacqueline Mersch et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Feelings About genomiC Testing Results (FACToR) Questionnaire: Development and Preliminary Validation

(2018) Meng Li et al.   Journal of Genetic Counseling

Recontacting clinical genetics patients with reclassified results: equity and policy challenges

(2018) Yvonne Bombard et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Patient re-contact after revision of genomic test results: points to consider—a statement of the American College of Medical Genetics and Genomics (ACMG)

(2018) Karen L. David et al.   GENETICS IN MEDICINE

Attitudes, knowledge and consequences of uncertain genetic findings in hypertrophic cardiomyopathy

(2017) Charlotte Burns et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Recontacting in clinical practice: the views and expectations of patients in the United Kingdom

(2017) Daniele Carrieri et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A 'joint venture' model of recontacting in clinical genomics: challenges for responsible implementation

(2017) Sandi Dheensa et al.   European Journal of Medical Genetics

“Possibly positive or certainly uncertain?”: participants’ responses to uncertain diagnostic results from exome sequencing

(2017) Debra Skinner et al.   GENETICS IN MEDICINE

Observed frequency and challenges of variant reclassification in a hereditary cancer clinic

(2017) Sarah Macklin et al.   GENETICS IN MEDICINE

Gaps in Incorporating Germline Genetic Testing Into Treatment Decision-Making for Early-Stage Breast Cancer

(2017) Allison W. Kurian et al.   JOURNAL OF CLINICAL ONCOLOGY

Lynch Syndrome Limbo: Patient Understanding of Variants of Uncertain Significance

(2017) Ilana Solomon et al.   Journal of Genetic Counseling

Examining the Psychosocial Impact of Genetic Testing for Cardiomyopathies

(2017) Julia Wynn et al.   Journal of Genetic Counseling

Impact of Panel Gene Testing for Hereditary Breast and Ovarian Cancer on Patients

(2017) Heidi S. Lumish et al.   Journal of Genetic Counseling

Known unknowns: building an ethics of uncertainty into genomic medicine

(2016) Ainsley J. Newson et al.   BMC Medical Genomics

Multi-gene panel testing for hereditary cancer susceptibility in a rural Familial Cancer Program

(2016) David J. Hermel et al.   Familial Cancer

Patient Recall, Interpretation, and Perspective of an Inconclusive Long QT Syndrome Genetic Test Result

(2016) Sarah Predham et al.   Journal of Genetic Counseling

Patient feedback and early outcome data with a novel tiered-binned model for multiplex breast cancer susceptibility testing

(2015) Angela R. Bradbury et al.   GENETICS IN MEDICINE

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

Adverse Events in Cancer Genetic Testing

(2014) Danielle C. Bonadies et al.   CANCER JOURNAL

Variants of uncertain significance inBRCAtesting: evaluation of surgical decisions, risk perception, and cancer distress

(2013) JO Culver et al.   CLINICAL GENETICS

The integration of next-generation sequencing panels in the clinical cancer genetics practice: an institutional experience

(2013) Caitlin B. Mauer et al.   GENETICS IN MEDICINE

“Grasping the Grey”: Patient Understanding and Interpretation of an Intermediate Allele Predictive Test Result for Huntington Disease

(2012) A. Semaka et al.   Journal of Genetic Counseling

Distress among women receiving uninformativeBRCA1/2results: 12-month outcomes

(2009) Suzanne C. O'Neill et al.   PSYCHO-ONCOLOGY

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE

The counsellees' view of an unclassified variant in BRCA1/2: recall, interpretation, and impact on life

(2007) Joël Vos et al.   PSYCHO-ONCOLOGY