Observed frequency and challenges of variant reclassification in a hereditary cancer clinic

Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

(2017) Karoline B. Kuchenbaecker et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Lynch Syndrome Limbo: Patient Understanding of Variants of Uncertain Significance

(2017) Ilana Solomon et al.   Journal of Genetic Counseling

Clinical Variant Classification: A Comparison of Public Databases and a Commercial Testing Laboratory

(2017) William Gradishar et al.   ONCOLOGIST

Performance of ACMG-AMP Variant-Interpretation Guidelines among Nine Laboratories in the Clinical Sequencing Exploratory Research Consortium

(2016) Laura M. Amendola et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Germline BRCA testing is moving from cancer risk assessment to a predictive biomarker for targeting cancer therapeutics

(2016) L. Moreno et al.   Clinical & Translational Oncology

Public variant databases: liability?

(2016) Adrian Thorogood et al.   GENETICS IN MEDICINE

Frequency of Germline Mutations in 25 Cancer Susceptibility Genes in a Sequential Series of Patients With Breast Cancer

(2016) Nadine Tung et al.   JOURNAL OF CLINICAL ONCOLOGY

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

Comparison of risk management strategies between women testing positive for a BRCA variant of unknown significance and women with known BRCA deleterious mutations

(2014) Christine Garcia et al.   GENETICS IN MEDICINE

Risk management options elected by women after testing positive for a BRCA mutation

(2013) Christine Garcia et al.   GYNECOLOGIC ONCOLOGY

Follow-up of carriers of BRCA1 and BRCA2 variants of unknown significance: Variant reclassification and surgical decisions

(2011) Mitzi L. Murray et al.   GENETICS IN MEDICINE

Differential use of available genetic tests among primary care physicians in the United States: results of a national survey

(2008) Alexandra E Shields et al.   GENETICS IN MEDICINE

Physicians’ Experiences With BRCA1/2 Testing in Community Settings

(2008) Nancy L. Keating et al.   JOURNAL OF CLINICAL ONCOLOGY

The counsellees' view of an unclassified variant in BRCA1/2: recall, interpretation, and impact on life

(2007) Joël Vos et al.   PSYCHO-ONCOLOGY