Article
Polymer Science
Misbah Iqbal, Muhammad Bilal Khan Niazi, Zaib Jahan, Tahir Ahmad, Zakir Hussain, Farooq Sher
Summary: The research conducted a comparative study on biodegradable membranes based on PVA, St, GO, and rGO for enhanced antibacterial and mechanical properties. By incorporating different concentrations of GO and rGO, two exceptional membranes were identified, prolonging the shelf life of gooseberries effectively.
Article
Biochemistry & Molecular Biology
Amer Ali Mahdi, Qais Ali Al-Maqtari, Waleed Al-Ansi, Wei Hu, Sulafa B. H. Hashim, Haiying Cui, Lin Lin
Summary: This study evaluated the effects of adding different concentrations (0%, 1%, 2%, and 3%) of peach gum (PG) to films made from polyethylene oxide (PEO) combined with Litsea cubeba essential oil (LCEO) for future use as active food packaging. The results showed that the film with 2% PG concentration had the best physical and mechanical properties. The addition of PG improved the glass transition temperature and resulted in films with brighter color, lower water vapor permeability, and the lowest water activity. Furthermore, PG films exhibited high antioxidant and antibacterial activity and maintained the quality of wrapped beef during storage.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Composites
Gulsum Aydin, Mualla Yildiz
Summary: This study investigated the effects of incorporating Hibiscus sabdariffa L. extract (HE) and graphene oxide (GO) into corn starch-based films on their physical, mechanical, and antibacterial properties. The results showed that the addition of HE and GO increased the thickness, moisture content, solubility, and swelling degree of the films. FTIR spectra and SEM images confirmed the compatibility between starch, HE, and GO. Furthermore, the films exhibited strong antibacterial activity against both Gram-positive and Gram-negative bacteria.
POLYMER COMPOSITES
(2022)
Article
Biochemistry & Molecular Biology
Kizkitza Gonzalez, Izaskun Larraza, Loli Martin, Arantxa Eceiza, Nagore Gabilondo
Summary: Plasticized starch nanocomposite films with graphene and graphene oxide were prepared using a casting method. The addition of graphene resulted in improved mechanical properties, while Salvia extracts acted as a co-plasticizer. The inclusion of graphene oxide showed strong interactions with starch and improved electrical conductivity compared to graphene.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Agricultural Engineering
Liqiang Xiao, Zheng Yao, Yongbin He, Zeyu Han, Xujing Zhang, Chengcheng Li, Pengwu Xu, Weijun Yang, Piming Ma
Summary: The lignin-zinc oxide hybrid particles were successfully synthesized using a hydrothermal method, and their addition to PBAT resulted in improved mechanical properties. The PBAT/LZn composite films exhibited UV shielding, antioxidant, and antibacterial activities, making them suitable for active food packaging.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Biochemistry & Molecular Biology
Wenkai Hu, Zhiming Zou, Heping Li, Ziang Zhang, Jingling Yu, Qun Tang
Summary: This study explored the use of rod-like ZnO nanofillers as compatibilizers in biodegradable PVA/ST film, resulting in improved physical and antibacterial properties while maintaining transparency. These nanocomposite films have great potential in the field of active food packaging.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Applied
Hao Xu, Long Chen, David Julian McClements, Hao Cheng, Jie Long, Zhengyu Jin
Summary: With increasing awareness of the environment and food safety, the development of biodegradable active food packaging has gained attention in recent years. Starch is considered a potential bio-material for producing biodegradable films. However, the functional performance of starch-based films is limited, hindering their application as food packaging materials. In this study, a simple green method was developed to improve the dispersibility of graphene in starch-based films. The addition of nanocomposites positively influenced the microstructure, mechanical properties, barrier properties, and thermal properties of the films. Additionally, the composite films exhibited antibacterial activity, showing their promising potential as active food packaging.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Multidisciplinary
Samsul Rizal, H. P. S. Abdul Khalil, Shazlina Abd Hamid, Esam Bashir Yahya, Ikramullah Ikramullah, Rudi Kurniawan, Che Mohamad Hazwan
Summary: In this study, cinnamon nanoparticles were incorporated into red seaweed biopolymer films using a solvent casting method. The addition of cinnamon nanoparticles improved the morphological, mechanical, thermal, wettability, and antimicrobial properties of the films.
Article
Food Science & Technology
Khwanchat Promhuad, Danaya Phothisarattana, Yeyen Laorenza, Nattinee Bumbudsanpharoke, Nathdanai Harnkarnsujarit
Summary: Enhancing the antimicrobial functions of biodegradable polyesters by adding zinc oxide nanoparticles and optimizing the molecular orientation of the polymer can improve the mechanical properties of the material and produce sustainable active nanocomposite packaging.
Article
Biochemistry & Molecular Biology
Wenlai Jiang, Ping Zhao, Wenliang Song, Menglong Wang, Deng-Guang Yu
Summary: The purpose of this study was to develop an antibacterial food packaging film with a novel ultrathin fibrous membrane having a core-sheath structure. The results showed that the fiber film had a fine morphology and structure, and exhibited synergistic antibacterial performance. The practical application demonstrated that the fiber film effectively prolonged the fresh-keeping period of cherry tomatoes.
Article
Polymer Science
Siti Hajar Othman, Nur Fitrah Liyana Othman, Ruzanna Ahmad Shapi'i, Siti Hajar Ariffin, Khairul Faezah Md. Yunos
Summary: This research developed corn starch/chitosan nanoparticles/thymol bio-nanocomposite films as potential food packaging materials to prolong food shelf life. Thymol addition increased water vapor permeability but decreased tensile strength and other mechanical properties of the films. The 3% thymol bio-nanocomposite films showed the most promising performance in extending the shelf life of cherry tomatoes.
Article
Biochemistry & Molecular Biology
Hao Xu, Jiaxu Li, David Julian Mcclements, Hao Cheng, Jie Long, Xinwen Peng, Zhenlin Xu, Man Meng, Yidong Zou, Guanxiong Chen, Zhengyu Jin, Long Chen
Summary: Starch films can be improved by incorporating eggshell powder, which enhances the hydrogen bonding and improves mechanical and barrier properties. Adding epigallocatechin gallate on the surface of porous eggshell powder further enhances the dispersibility and improves UV screening, water vapor and oxygen barrier properties, as well as antibacterial activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Nanoscience & Nanotechnology
Ashwini G. Patil
Summary: The research developed a novel nanocomposite using microbes, showing excellent antibacterial activity with controlled release and remarkable stability in vitro.
Article
Chemistry, Multidisciplinary
Shengxue Zhou, Xiaosong Zhai, Rui Zhang, Wentao Wang, Loong-Tak Lim, Hanxue Hou
Summary: Antimicrobial films based on starch, poly(butylene adipate-co-terephthalate) (PBAT), and AgNPs@SiO2 were produced with good compatibility and antibacterial activities. The composite films loaded with 1 wt% AgNPs@SiO2 showed nearly 90% inhibition efficiency on Staphylococcus aureus and Escherichia coli, and exhibited extended shelf life for peaches and nectarines. The high-throughput production method and strong antibacterial activities make them promising for commercial applications as antimicrobial packaging materials.
Article
Chemistry, Applied
Yongsheng Ni, Jing Sun, Jianlong Wang
Summary: This paper presents a new strategy for developing konjac glucomannan-based antibacterial films with a broad-spectrum antibacterial activity. The films, incorporating CNMo nanocomposites, show excellent performances in terms of structural, mechanical, and thermal properties, as well as hydrophobicity, prolonging the shelf life of cherry tomatoes. Hemolysis and cells experiment confirm the safety of the film, indicating potential applications in antibacterial packaging.
CARBOHYDRATE POLYMERS
(2021)
Review
Materials Science, Textiles
Kannan Badri Narayanan, Natarajan Sakthivel, Sung Soo Han
Summary: Metal- and carbon-based nanoparticles with unique nanometric dimensions have diverse physical and chemical properties, and can be synthesized through green methods using plants and microorganisms. These nanomaterials have a wide range of applications in fields such as chemical catalysis, cancer treatment, antimicrobial activities, and bioimaging.
FIBERS AND POLYMERS
(2021)
Article
Chemistry, Physical
Priyanka Raju Thomball, Kummara Madhusudana Rao, Sunmi Zo, Kannan Badri Narayanan, Raju S. Thombal, Sung Soo Han
Summary: A highly efficient nitrogen-doped carbon sheet-like material (NCS) is developed via simple pyrolysis, which shows excellent catalytic activity towards the reduction of nitro-compounds and can be easily recovered and reused multiple times.
Article
Environmental Sciences
Kanagavel Susithra, Kannan Badri Narayanan, Uthandakalaipandian Ramesh, Chellaiah Edward Raja, Gandhi Premkumar, Govindaraju Varatharaju, Arunachalam Vijayakumar, Marikani Kannan, Kaniappan Rajarathinam
Summary: Poly-beta-hydroxybutyrate (PHB), a natural polyester, was produced by bacteria isolated from soil samples in this study. By optimizing factors, such as the use of alkali-pretreated spent mushroom substrate, the PHB production was increased. This research demonstrates the potential use of lignocellulosic agro-waste materials as a cost-effective feedstock for biodegradable PHB production.
WASTE AND BIOMASS VALORIZATION
(2021)
Article
Chemistry, Multidisciplinary
Kannan Badri Narayanan, So Yeon Won, K. Narayanan Rajnish, Sung Soo Han
Summary: The study demonstrated the synthesis of reduced graphene oxide using Aspergillus sp. filtrate and its characterization. The Aspergillus sp. filtrate-RGO showed significant antibacterial activity against pathogenic bacteria. This fungal filtrate-mediated RGO synthesis is a promising antibacterial carbon nanomaterial for biomedical and nanotechnological applications.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2021)
Review
Biotechnology & Applied Microbiology
Kannan Badri Narayanan, Sung Soo Han
Summary: The fabrication of novel biomaterial scaffolds with improved biological interactions and mechanical properties is crucial for tissue engineering. Protein/peptide-based polymeric scaffolds, especially those created through bioorthogonal enzymatic reactions, show great potential in replicating the in vivo microenvironment for cell differentiation and tissue formation. Peptide ligases, including natural ones like sortases and butelase 1, as well as engineered ones like trypsiligase and subtiligase, are efficient tools for enzymatic cross-linking of protein/peptide-based polymeric chains. These ligases can enhance cell attachment, growth, and differentiation by conjugating with cell-adhesive ECM proteins or motifs and growth factors. The review discusses the potential, limitations, and mechanisms of natural and engineered peptide ligases in the fabrication of (bio)polymeric scaffolds for various tissue engineering and regenerative applications.
ENZYME AND MICROBIAL TECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Shaukat Khan, Mazhar Ul-Islam, Muhammad Wajid Ullah, Youlong Zhu, Kannan Badri Narayanan, Sung Soo Han, Joong Kon Park
Summary: This review summarizes the techniques used to develop 3D bacterial cellulose (BC) scaffolds and discusses their potential biomedical applications. It provides comprehensive coverage of the idea, requirements, synthetic strategies, and current and prospective applications of 3D BC scaffolds, making it useful for researchers working with polysaccharides, biopolymers, or composite materials.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Pharmacology & Pharmacy
Kummara Madhusudana Rao, Kannan Badri Narayanan, Uluvangada Thammaiah Uthappa, Pil-Hoon Park, Inho Choi, Sung Soo Han
Summary: In this study, multifunctional fungal mushroom-derived hydrogels were developed for wound dressing applications, with tissue adhesive, hemostasis, self-healing, and antibacterial properties. The hydrogels exhibited good swelling ratio, biodegradability, mechanical properties, and high adhesion strength to porcine skin. Additionally, they showed excellent antibacterial properties and promoted cell viability and attachment, making them a promising material for wound healing.
Article
Multidisciplinary Sciences
Abdulrahman Ahmed Sharwani, Kannan Badri Narayanan, Mohammad Ehtisham Khan, Sung Soo Han
Summary: This study successfully synthesized silver-loaded zinc oxide nanocomposites with unique morphologies and demonstrated their photocatalytic and antimicrobial abilities. These materials possess high thermal stability and large surface area, and show efficient degradation and bactericidal effects on various pollutants.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Multidisciplinary
Prakash Shrestha, Shiva Pathak, Shobha Regmi, Kannan Badri Narayanan, Tiep Tien Nguyen, Simmyung Yook, Jong Oh Kim, Jee-Heon Jeong
Summary: Extracellular matrix (ECM) is crucial for cell biology, and artificial microfibers mimicking ECM can enhance cell-polymeric fiber interactions and improve cell viability. Loading antioxidant drugs into microfibers further enhances cell viability.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2022)
Review
Pharmacology & Pharmacy
Kannan Badri Narayanan, Rakesh Bhaskar, Sung Soo Han
Summary: Nanogels (NGs), a significant nanoplatform with properties of both hydrogels and nanoparticles, have been extensively used for controlled/sustained delivery of therapeutic agents in biomedical and healthcare applications. This review summarizes the synthesis and functionalization strategies of NGs and highlights their recent advances in various biomedical fields such as cancer theranostics, immunotherapy, sensing, and tissue engineering.
Article
Materials Science, Multidisciplinary
Madeshwaran Sekkarapatti Ramasamy, Rakesh Bhaskar, Kannan Badri Narayanan, Shiv Dutt Purohit, Sang Shin Park, Amutheesan Manikkavel, Byungki Kim, Sung Soo Han
Summary: This study reports a method to fabricate nanofiber scaffolds with improved piezoelectric responses, surface properties, and cytocompatibility. The modified scaffolds showed enhanced mechanical properties and hydrophilicity compared to the original scaffolds, and had higher cell attachment and proliferation abilities. These scaffolds have potential applications in tissue growth and regeneration, medical detection, and biological force sensing.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Microbiology
Kannan Badri Narayanan, Rakesh Bhaskar, Yong Joo Seok, Sung Soo Han
Summary: The biological synthesis of nanocomposites provides a cost-effective and environmentally friendly way to produce materials with enhanced properties. In this study, zinc oxide and silver/zinc oxide nanocomposites were biosynthesized using the cell-free filtrate of Lysinibacillus sphaericus, and their properties were characterized using various techniques. The nanocomposites showed improved photocatalytic efficiency, cytotoxicity against cancer cells, and antibacterial activity, making them promising materials for biomedical and environmental applications.
Review
Neurosciences
Shampa Ghosh, Jitendra Kumar Sinha, Soumya Ghosh, Hitaishi Sharma, Rakesh Bhaskar, Kannan Badri Narayanan
Summary: This comprehensive review explores innovative therapies for epilepsy management, including responsive neurostimulation, vagus nerve stimulation, deep brain stimulation, gene therapies, and optogenetics. It also discusses adjunctive therapies like cannabidiol and the ketogenic diet. The importance of staying updated with emerging trends in epilepsy management is emphasized, along with the hope for improved therapeutic options.
Article
Polymer Science
Kannan Badri Narayanan, Rakesh Bhaskar, Kuncham Sudhakar, Dong Hyun Nam, Sung Soo Han
Summary: In this study, BC hydrogel was functionalized with PDA and used in skin tissue engineering. Characterization techniques were used to investigate the formation of PDA on BC nanofibers. The BC/PDA hydrogels showed excellent tensile strength, water-wetting ability, and enhanced cell viability, making them potential biocompatible alternatives for skin tissue engineering and wound-dressing applications.
Review
Biotechnology & Applied Microbiology
Shivani Singh, Saptashwa Datta, Kannan Badri Narayanan, K. Narayanan Rajnish
Summary: Bacterial biofilms are structures with high antibiotic resistance, where quorum sensing and multi-drug resistance efflux pumps play important roles in regulating the internal environment of the biofilm and formation of the biofilm. Studies have shown the critical role of exopolysaccharides in biofilm formation and its importance in antibiotic resistance.
JOURNAL OF GENETIC ENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
