An injectable hydrogel‐formulated inhibitor of prolyl‐4‐hydroxylase promotes T regulatory cell recruitment and enhances alveolar bone regeneration during resolution of experimental periodontitis

The secreted protein DEL-1 activates a β3 integrin–FAK–ERK1/2–RUNX2 pathway and promotes osteogenic differentiation and bone regeneration

(2020) Da-Yo Yuh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-663 antagonizes apoptosis antagonizing transcription factor to induce apoptosis in epithelial cells

(2019) M. R. Benakanakere et al.   APOPTOSIS

Nonsurgical therapy for teeth and implants—When and why?

(2019) Niklaus P. Lang et al.   PERIODONTOLOGY 2000

Systemic silencing of Phd2 causes reversible immune regulatory dysfunction

(2019) Atsushi Yamamoto et al.   JOURNAL OF CLINICAL INVESTIGATION

Drug delivery and epimorphic salamander-type mouse regeneration: A full parts and labor plan

(2018) Ellen Heber-Katz et al.   ADVANCED DRUG DELIVERY REVIEWS

Advances in Hypoxia-Inducible Factor Biology

(2018) Hani Choudhry et al.   Cell Metabolism

Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration

(2018) Jiatao Li et al.   Frontiers in Immunology

Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine

(2018) Kevin Dzobo et al.   Stem Cells International

The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression

(2018) Abdul Malik Tyagi et al.   IMMUNITY

DEL-1 promotes macrophage efferocytosis and clearance of inflammation

(2018) Ioannis Kourtzelis et al.   NATURE IMMUNOLOGY

The oral microbiota: dynamic communities and host interactions

(2018) Richard J. Lamont et al.   NATURE REVIEWS MICROBIOLOGY

A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans

(2018) Nicolas Dutzan et al.   Science Translational Medicine

Hypoxia-Inducible Factor Prolyl 4-Hydroxylases and Metabolism

(2018) Peppi Koivunen et al.   TRENDS IN MOLECULAR MEDICINE

Global epidemiology of dental caries and severe periodontitis - a comprehensive review

(2017) Jo E. Frencken et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Oxygen, Metabolism, and Regeneration: Lessons from Mice

(2017) Ellen Heber-Katz   TRENDS IN MOLECULAR MEDICINE

Periodontal diseases

(2017) Denis F. Kinane et al.   Nature Reviews Disease Primers

Mesenchymal stem cells homing to improve bone healing

(2017) Weiping Lin et al.   Journal of Orthopaedic Translation

Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration

(2016) Fuqin Fan et al.   Science Translational Medicine

A Distinct Function of Regulatory T Cells in Tissue Protection

(2015) Nicholas Arpaia et al.   CELL

Hypoxia-Inducible Factor-1: A Critical Player in the Survival Strategy of Stressed Cells

(2015) Shuyang Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Emerging Regenerative Approaches for Periodontal Reconstruction: A Consensus Report From the AAP Regeneration Workshop

(2015) David L. Cochran et al.   JOURNAL OF PERIODONTOLOGY

Emerging Regenerative Approaches for Periodontal Reconstruction: A Systematic Review From the AAP Regeneration Workshop

(2015) Zhao Lin et al.   JOURNAL OF PERIODONTOLOGY

Update on Prevalence of Periodontitis in Adults in the United States: NHANES 2009 to 2012

(2015) Paul I. Eke et al.   JOURNAL OF PERIODONTOLOGY

Biomaterials for promoting periodontal regeneration in human intrabony defects: a systematic review

(2015) Anton Sculean et al.   PERIODONTOLOGY 2000

DEL-1 restrains osteoclastogenesis and inhibits inflammatory bone loss in nonhuman primates

(2015) Jieun Shin et al.   Science Translational Medicine

Drug-induced regeneration in adult mice

(2015) Yong Zhang et al.   Science Translational Medicine

Antagonistic effects of IL-17 and D-resolvins on endothelial Del-1 expression through a GSK-3β-C/EBPβ pathway

(2015) Tomoki Maekawa et al.   Nature Communications

Global Burden of Severe Periodontitis in 1990-2010

(2014) N.J. Kassebaum et al.   JOURNAL OF DENTAL RESEARCH

Proresolving Nanomedicines Activate Bone Regeneration in Periodontitis

(2014) T.E. Van Dyke et al.   JOURNAL OF DENTAL RESEARCH

Active players in resolution of shock/sepsis induced indirect lung injury: immunomodulatory effects of Tregs and PD-1

(2014) Lunxian Tang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Time to take periodontitis seriously

(2014) I. L. C. Chapple   BMJ-British Medical Journal

The Role of Hypoxia-Inducible Factor in Wound Healing

(2014) Wan Xing Hong et al.   Advances in Wound Care

Impact of periodontal disease and periodontal therapy on oral health-related quality of life

(2013) Fabian Brauchle et al.   INTERNATIONAL DENTAL JOURNAL

Transient inhibition of connective tissue infiltration and collagen deposition into porous poly(lactic-co-glycolic acid) discs

(2013) Ryan J. Love et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

In vivo Identification of Periodontal Progenitor Cells

(2013) H. Roguljic et al.   JOURNAL OF DENTAL RESEARCH

Optimization of the ligature-induced periodontitis model in mice

(2013) Toshiharu Abe et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Impact of Periodontal Therapy on the Subgingival Microbiota of Severe Periodontitis: Comparison Between Good Responders and Individuals With Refractory Periodontitis Using the Human Oral Microbe Identification Microarray

(2012) Ana Paula V. Colombo et al.   JOURNAL OF PERIODONTOLOGY

The Ubiquitin-Proteasome System Meets Angiogenesis

(2012) N. Rahimi   MOLECULAR CANCER THERAPEUTICS

Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

(2012) E. T. Clambey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diabetes aggravates periodontitis by limiting repair through enhanced inflammation

(2011) Sandra Pacios et al.   FASEB JOURNAL

Biological approaches to the development of novel periodontal therapies - Consensus of the Seventh European Workshop on Periodontology

(2011) Maurizio S. Tonetti et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Mesenchymal stem cell–based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α

(2011) Yi Liu et al.   NATURE MEDICINE

Periodontal tissue regeneration by signaling molecule(s): what role does basic fibroblast growth factor (FGF-2) have in periodontal therapy?

(2011) Shinya Murakami   PERIODONTOLOGY 2000

Expression of Hypoxia-Inducible Factor-1α in Human Periodontal Tissue

(2010) King-Tung Ng et al.   JOURNAL OF PERIODONTOLOGY

Oral biofilm-associated diseases: trends and implications for quality of life, systemic health and expenditures

(2010) Thomas Beikler et al.   PERIODONTOLOGY 2000

Epidemiologic patterns of chronic and aggressive periodontitis

(2010) Ryan T. Demmer et al.   PERIODONTOLOGY 2000

Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF

(2009) Ernestina Schipani et al.   JOURNAL OF BONE AND MINERAL RESEARCH

CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury

(2009) Franco R. D’Alessio et al.   JOURNAL OF CLINICAL INVESTIGATION

Defining a visual marker of osteoprogenitor cells within the periodontium

(2009) S. M. San Miguel et al.   JOURNAL OF PERIODONTAL RESEARCH

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Regeneration of periodontal tissues: combinations of barrier membranes and grafting materials - biological foundation and preclinical evidence: A systematic review

(2008) Anton Sculean et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Activation of the hypoxia-inducible factor-1  pathway accelerates bone regeneration

(2008) C. Wan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA