Induction of TGF‐β receptor I expression in a DNA methylation‐independent manner mediated by DNMT3A downregulation is involved in early‐onset severe preeclampsia

Unveiling the role of microRNA-7 in linking TGF-β–Smad-mediated epithelial-mesenchymal transition with negative regulation of trophoblast invasion

(2019) Jin-Chung Shih et al.   FASEB JOURNAL

Bioinformatics approach reveals the critical role of TGF-β signaling pathway in pre-eclampsia development

(2019) Kejia Wu et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

WOX11 recruits a histone H3K27me3 demethylase to promote gene expression during shoot development in rice

(2018) Saifeng Cheng et al.   NUCLEIC ACIDS RESEARCH

Regulation of Breast Cancer-Induced Osteoclastogenesis by MacroH2A1.2 Involving EZH2-Mediated H3K27me3

(2018) Jinman Kim et al.   Cell Reports

The Attenuation of Trophoblast Invasion Caused by the Downregulation of EZH2 is Involved in the Pathogenesis of Human Recurrent Miscarriage

(2018) Shijian Lv et al.   Molecular Therapy-Nucleic Acids

TGF-β1 Inhibits Human Trophoblast Cell Invasion by Upregulating Connective Tissue Growth Factor Expression

(2017) Jung-Chien Cheng et al.   ENDOCRINOLOGY

Dysregulated DNA Methyltransferase 3A Upregulates IGFBP5 to Suppress Trophoblast Cell Migration and Invasion in PreeclampsiaNovelty and Significance

(2017) Yuanhui Jia et al.   HYPERTENSION

Multiple Soluble TGF-β Receptors in Addition to Soluble Endoglin Are Elevated in Preeclamptic Serum and They Synergistically Inhibit TGF-β Signaling

(2017) Yao Wang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons

(2017) Jian-Yuan Zhao et al.   Nature Communications

c-Myc is Required for BRAFV600E-Induced Epigenetic Silencing by H3K27me3 in Tumorigenesis

(2017) Yiping Qu et al.   Theranostics

Maternal DNA Methylation Regulates Early Trophoblast Development

(2016) Miguel R. Branco et al.   DEVELOPMENTAL CELL

Placental Growth Factor Administration Abolishes Placental Ischemia-Induced HypertensionNovelty and Significance

(2016) Frank T. Spradley et al.   HYPERTENSION

Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a

(2016) Staci L. Haney et al.   Cell Reports

Why is placentation abnormal in preeclampsia?

(2015) Susan J. Fisher   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis

(2015) S L Haney et al.   ONCOGENE

Uterine activin receptor-like kinase 5 is crucial for blastocyst implantation and placental development

(2015) Jia Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetics and Preeclampsia: Defining Functional Epimutations in the Preeclamptic Placenta Related to the TGF-β Pathway

(2015) Elizabeth Martin et al.   PLoS One

Reduced uterine perfusion pressure induces hypertension in the pregnant mouse

(2014) Suttira Intapad et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Global and regional estimates of preeclampsia and eclampsia: a systematic review

(2013) Edgardo Abalos et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Regulation of Lineage Specific DNA Hypomethylation in Mouse Trophectoderm

(2013) Masaaki Oda et al.   PLoS One

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

Evaluation and management of severe preeclampsia before 34 weeks' gestation

(2011) Baha M. Sibai   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity

(2011) Matthew D. Young et al.   NUCLEIC ACIDS RESEARCH

Improving RNA-Seq expression estimates by correcting for fragment bias

(2011) Adam Roberts et al.   GENOME BIOLOGY

Targeting of EZH2 to a defined genomic site is sufficient for recruitment of Dnmt3a but not de novo DNA methylation

(2010) Margaret Rush et al.   Epigenetics

DNMT3a plays a role in switches between doxorubicin-induced senescence and apoptosis of colorectal cancer cells

(2010) Yu Zhang et al.   INTERNATIONAL JOURNAL OF CANCER

Pre-eclampsia

(2010) Eric AP Steegers et al.   LANCET

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

TGFβ1 Attenuates Expression of Prolactin and IGFBP-1 in Decidualized Endometrial Stromal Cells by Both SMAD-Dependent and SMAD-Independent Pathways

(2010) Nicole M. Kane et al.   PLoS One

Mechanisms of Polycomb gene silencing: knowns and unknowns

(2009) Jeffrey A. Simon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stem cell regulation by polycomb repressors: postponing commitment

(2008) Alexandra M Pietersen et al.   CURRENT OPINION IN CELL BIOLOGY

Profiling Gene Expression in Human Placentae of Different Gestational Ages: An OPRU* Network and UW SCOR Study

(2008) Andrei M. Mikheev et al.   Reproductive Sciences

Programming of gene expression by Polycomb group proteins

(2008) Claudia Köhler et al.   TRENDS IN CELL BIOLOGY