Nanoparticle-mediated therapeutic compounds delivery to glioblastoma

Small-sized gadolinium oxide based nanoparticles for high-efficiency theranostics of orthotopic glioblastoma

(2020) Zheyu Shen et al.   BIOMATERIALS

Gene Therapy Using Neural Stem/Progenitor Cells Derived from Human Induced Pluripotent Stem Cells: Visualization of Migration and Bystander Killing Effect

(2020) Ryota Tamura et al.   HUMAN GENE THERAPY

Aptamer-Conjugated Gold Nanoparticles Targeting Epidermal Growth Factor Receptor Variant III for the Treatment of Glioblastoma

(2020) Li Peng et al.   International Journal of Nanomedicine

Intelligent Nanocomposites with Intrinsic Blood–Brain‐Barrier Crossing Ability Designed for Highly Specific MR Imaging and Sonodynamic Therapy of Glioblastoma

(2020) Kaicheng Liang et al.   Small

Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways

(2020) Xiangqi Meng et al.   Nature Communications

Tumor-penetrating peptide for systemic targeting of Tenascin-C

(2020) Prakash Lingasamy et al.   Scientific Reports

Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules

(2020) Seetha Harilal et al.   BRAIN RESEARCH BULLETIN

Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy

(2019) Gulsah Erel-Akbaba et al.   ACS Nano

Brain and bone cancer targeting by a ferrofluid composed of superparamagnetic iron-oxide/silica/carbon nanoparticles (earthicles)

(2019) Victoria M. Wu et al.   Acta Biomaterialia

Magnetic targeting combined with active targeting of dual-ligand iron oxide nanoprobes to promote the penetration depth in tumors for effective magnetic resonance imaging and hyperthermia

(2019) Ling Chen et al.   Acta Biomaterialia

ROS‐Responsive Polymeric siRNA Nanomedicine Stabilized by Triple Interactions for the Robust Glioblastoma Combinational RNAi Therapy

(2019) Meng Zheng et al.   ADVANCED MATERIALS

Improving glioblastoma therapeutic outcomes via doxorubicin-loaded nanomicelles modified with borneol

(2019) Lingwei Meng et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Peptide-guided nanoparticles for glioblastoma targeting

(2019) Pille Säälik et al.   JOURNAL OF CONTROLLED RELEASE

Enhanced Efficacy of Temozolomide Loaded by a Tetrahedral Framework DNA Nanoparticle in the Therapy for Glioblastoma

(2019) Wei Fu et al.   ACS Applied Materials & Interfaces

Intranasal delivery of targeted polyfunctional gold–iron oxide nanoparticles loaded with therapeutic microRNAs for combined theranostic multimodality imaging and presensitization of glioblastoma to temozolomide

(2019) Uday K. Sukumar et al.   BIOMATERIALS

Effects of human placenta‐derived mesenchymal stem cells with NK4 gene expression on glioblastoma multiforme cell lines

(2019) Zahra Jabbarpour et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma

(2019) Peng Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pifithrin-μ incorporated in gold nanoparticle amplifies pro-apoptotic unfolded protein response cascades to potentiate synergistic glioblastoma therapy

(2019) Haitao Zhu et al.   BIOMATERIALS

Myristic Acid-Modified DA7R Peptide for Whole-Process Glioma-Targeted Drug Delivery

(2018) Man Ying et al.   ACS Applied Materials & Interfaces

Protein Toxin Chaperoned by LRP-1-Targeted Virus-Mimicking Vesicles Induces High-Efficiency Glioblastoma Therapy In Vivo

(2018) Yu Jiang et al.   ADVANCED MATERIALS

pH driven precipitation of quisinostat onto PLA-PEG nanoparticles enables treatment of intracranial glioblastoma

(2018) Kyle T. Householder et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Stem cells as vehicles and targets of nanoparticles

(2018) Sonia Pinho et al.   DRUG DISCOVERY TODAY

Transferrin-targeted, resveratrol-loaded liposomes for the treatment of glioblastoma

(2018) Aditi Jhaveri et al.   JOURNAL OF CONTROLLED RELEASE

Dual-targeting immunoliposomes using angiopep-2 and CD133 antibody for glioblastoma stem cells

(2018) Jung Seok Kim et al.   JOURNAL OF CONTROLLED RELEASE

Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating miRNAs Inhibit Glioblastoma Growth and Prolong Survival

(2018) Hernando Lopez-Bertoni et al.   NANO LETTERS

Monocyte-mediated chemotherapy drug delivery in glioblastoma

(2018) Chao Wang et al.   Nanomedicine

Nanoparticle crossing of blood–brain barrier: a road to new therapeutic approaches to central nervous system diseases

(2018) Valentín Ceña et al.   Nanomedicine

LPA signaling is regulated through the primary cilium: a novel target in glioblastoma

(2018) Yuriy V. Loskutov et al.   ONCOGENE

Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers

(2018) Xuebo Dou et al.   Scientific Reports

Targeted Delivery of Functionalized Upconversion Nanoparticles for Externally Triggered Photothermal/Photodynamic Therapies of Brain Glioblastoma

(2018) Yuan-Chung Tsai et al.   Theranostics

Overcoming blood–brain barrier by HER2-targeted nanosystem to suppress glioblastoma cell migration, invasion and tumor growth

(2018) Zhenhuan Song et al.   Journal of Materials Chemistry B

Delivery of siRNA in vitro and in vivo using PEI-capped porous silicon nanoparticles to silence MRP1 and inhibit proliferation in glioblastoma

(2018) Wing Yin Tong et al.   JOURNAL OF NANOBIOTECHNOLOGY

Enhanced Delivery of Therapeutic siRNA into Glioblastoma Cells Using Dendrimer-Entrapped Gold Nanoparticles Conjugated with β-Cyclodextrin

(2018) Jieru Qiu et al.   Nanomaterials

Cell-permeable NF-κB inhibitor-conjugated liposomes for treatment of glioma

(2018) Yanyu Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Augmentation of the Enhanced Permeability and Retention Effect with Nitric Oxide-Generating Agents Improves the Therapeutic Effects of Nanomedicines

(2018) Waliul Islam et al.   MOLECULAR CANCER THERAPEUTICS

Chemotherapy sensitization of glioblastoma by focused ultrasound-mediated delivery of therapeutic liposomes

(2018) Alexandros Papachristodoulou et al.   JOURNAL OF CONTROLLED RELEASE

Enhanced delivery of paclitaxel liposomes using focused ultrasound with microbubbles for treating nude mice bearing intracranial glioblastoma xenografts

(2017) Yuanyuan Shen et al.   International Journal of Nanomedicine

Tumortropic adipose-derived stem cells carrying smart nanotherapeutics for targeted delivery and dual-modality therapy of orthotopic glioblastoma

(2017) Wen-Chia Huang et al.   JOURNAL OF CONTROLLED RELEASE

Aptamer Functionalization of Nanosystems for Glioblastoma Targeting through the Blood–Brain Barrier

(2017) Ilaria Monaco et al.   JOURNAL OF MEDICINAL CHEMISTRY

Delivering siRNA and Chemotherapeutic Molecules Across BBB and BTB for Intracranial Glioblastoma Therapy

(2017) Zhen-zhen Yang et al.   MOLECULAR PHARMACEUTICS

iNGR-Modified Liposomes for Tumor Vascular Targeting and Tumor Tissue Penetrating Delivery in the Treatment of Glioblastoma

(2017) Jing-e Zhou et al.   MOLECULAR PHARMACEUTICS

Use of nanoparticles for glioblastoma treatment: a new approach

(2017) Pablo Játiva et al.   Nanomedicine

Radioiodine-labeled anti-epidermal growth factor receptor binding bovine serum albumin-polycaprolactone for targeting imaging of glioblastoma

(2017) Chengxia Li et al.   ONCOLOGY REPORTS

Drug Delivery to the Brain across the Blood-Brain Barrier Using Nanomaterials

(2017) Yung-Hao Tsou et al.   Small

Multifunctional targeted liposomal drug delivery for efficient glioblastoma treatment

(2017) Zakia Belhadj et al.   Oncotarget

Tumor homing and penetrating peptide-conjugated niosomes as multi-drug carriers for tumor-targeted drug delivery

(2017) Didem Ag Seleci et al.   RSC Advances

Multifunctional PEI-entrapped gold nanoparticles enable efficient delivery of therapeutic siRNA into glioblastoma cells

(2017) Lingdan Kong et al.   Biomaterials Science

Magnetic targeting with superparamagnetic iron oxide nanoparticles for in vivo glioma

(2017) Marina Fontes de Paula Aguiar et al.   Nanotechnology Reviews

A Combined Approach Employing Chlorotoxin-Nanovectors and Low Dose Radiation To Reach Infiltrating Tumor Niches in Glioblastoma

(2016) Matteo Tamborini et al.   ACS Nano

Synergistic targeting tenascin C and neuropilin-1 for specific penetration of nanoparticles for anti-glioblastoma treatment

(2016) Ting Kang et al.   BIOMATERIALS

Functionalized nanogels carrying an anticancer microRNA for glioblastoma therapy

(2016) Zohar Shatsberg et al.   JOURNAL OF CONTROLLED RELEASE

Cell Mediated Photothermal Therapy of Brain Tumors

(2016) Henry Hirschberg et al.   Journal of Neuroimmune Pharmacology

KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study

(2016) Ronan T. Swords et al.   LEUKEMIA RESEARCH

Nanoparticles for brain-specific drug and genetic material delivery, imaging and diagnosis

(2016) Inmaculada Posadas et al.   Nanomedicine

Dynamic In Vivo SPECT Imaging of Neural Stem Cells Functionalized with Radiolabeled Nanoparticles for Tracking of Glioblastoma

(2015) S.-H. Cheng et al.   JOURNAL OF NUCLEAR MEDICINE

ANG4043, a Novel Brain-Penetrant Peptide-mAb Conjugate, Is Efficacious against HER2-Positive Intracranial Tumors in Mice

(2014) A. Regina et al.   MOLECULAR CANCER THERAPEUTICS

Liposomes modified with P-aminophenyl-α-d-mannopyranoside: A carrier for targeting cerebral functional regions in mice

(2013) Zhong-fei Hao et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The biology of brain metastases—translation to new therapies

(2011) April F. Eichler et al.   Nature Reviews Clinical Oncology