Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5

Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism

(2014) Laura J Pettit et al.   BMC GENOMICS

The HtrA-Like Protease CD3284 Modulates Virulence of Clostridium difficile

(2014) Dennis Bakker et al.   INFECTION AND IMMUNITY

New opportunities for improved ribotyping of C. difficile clinical isolates by exploring their genomes

(2013) Volker Gürtler et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data

(2013) Chen-Shan Chin et al.   NATURE METHODS

Expanding the Repertoire of Gene Tools for Precise Manipulation of the Clostridium difficile Genome: Allelic Exchange Using pyrE Alleles

(2013) Yen Kuan Ng et al.   PLoS One

Horizontal gene transfer converts non-toxigenic Clostridium difficile strains into toxin producers

(2013) Michael S.M. Brouwer et al.   Nature Communications

Hype or hypervirulence

(2013) Wiep Klaas Smits   Virulence

Precise Manipulation of the Clostridium difficile Chromosome Reveals a Lack of Association between thetcdCGenotype and Toxin Production

(2012) Stephen T. Cartman et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Clostridium difficile Toxins: Mediators of Inflammation

(2012) Aimee Shen   Journal of Innate Immunity

Emergence and global spread of epidemic healthcare-associated Clostridium difficile

(2012) Miao He et al.   NATURE GENETICS

Mind the Gap: Upgrading Genomes with Pacific Biosciences RS Long-Read Sequencing Technology

(2012) Adam C. English et al.   PLoS One

C. difficile 630Δerm Spo0A Regulates Sporulation, but Does Not Contribute to Toxin Production, by Direct High-Affinity Binding to Target DNA

(2012) Katharina E. Rosenbusch et al.   PLoS One

DREME: motif discovery in transcription factor ChIP-seq data

(2011) Timothy L. Bailey   BIOINFORMATICS

Genetic Organisation, Mobility and Predicted Functions of Genes on Integrated, Mobile Genetic Elements in Sequenced Strains of Clostridium difficile

(2011) Michael S. M. Brouwer et al.   PLoS One

The Clostridium difficile Cell Wall Protein CwpV is Antigenically Variable between Strains, but Exhibits Conserved Aggregation-Promoting Function

(2011) Catherine B. Reynolds et al.   PLoS Pathogens

Demonstration of Conjugative Transposon (Tn5397)-Mediated Horizontal Gene Transfer between Clostridium difficile and Enterococcus faecalis

(2010) A. S. Jasni et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mutagenesis of the modified bases, m5U1939 and ψ2504, in Escherichia coli 23S rRNA

(2010) Clive Persaud et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Stampy: A statistical algorithm for sensitive and fast mapping of Illumina sequence reads

(2010) G. Lunter et al.   GENOME RESEARCH

Spatial Regulation of Histidine Kinases Governing Biofilm Formation in Bacillus subtilis

(2010) A. L. McLoon et al.   JOURNAL OF BACTERIOLOGY

Direct detection of DNA methylation during single-molecule, real-time sequencing

(2010) Benjamin A Flusberg et al.   NATURE METHODS

progressiveMauve: Multiple Genome Alignment with Gene Gain, Loss and Rearrangement

(2010) Aaron E. Darling et al.   PLoS One

Evolutionary dynamics of Clostridium difficile over short and long time scales

(2010) M. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Epigenetic regulation of the bacterial cell cycle

(2009) Justine Collier   CURRENT OPINION IN MICROBIOLOGY

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

A novel genetic switch controls phase variable expression of CwpV, aClostridium difficilecell wall protein

(2009) Jenny E. Emerson et al.   MOLECULAR MICROBIOLOGY

Clostridium difficile infection: new developments in epidemiology and pathogenesis

(2009) Maja Rupnik et al.   NATURE REVIEWS MICROBIOLOGY

Artemis and ACT: viewing, annotating and comparing sequences stored in a relational database

(2008) Tim Carver et al.   BIOINFORMATICS

The Origins of 168, W23, and Other Bacillus subtilis Legacy Strains

(2008) D. R. Zeigler et al.   JOURNAL OF BACTERIOLOGY

High-Precision, Whole-Genome Sequencing of Laboratory Strains Facilitates Genetic Studies

(2008) Anjana Srivatsan et al.   PLoS Genetics