Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism

Functional Characterization of Clostridium difficile Spore Coat Proteins

(2013) P. Permpoonpattana et al.   JOURNAL OF BACTERIOLOGY

The Clostridium difficile cpr Locus Is Regulated by a Noncontiguous Two-Component System in Response to Type A and B Lantibiotics

(2013) J. M. Suarez et al.   JOURNAL OF BACTERIOLOGY

Effect of an Oxygen-Tolerant Bifurcating Butyryl Coenzyme A Dehydrogenase/Electron-Transferring Flavoprotein Complex from Clostridium difficile on Butyrate Production in Escherichia coli

(2013) E.-H. Aboulnaga et al.   JOURNAL OF BACTERIOLOGY

The agr Locus Regulates Virulence and Colonization Genes in Clostridium difficile 027

(2013) M. J. Martin et al.   JOURNAL OF BACTERIOLOGY

SpoIVA and SipL Are Clostridium difficile Spore Morphogenetic Proteins

(2013) E. E. Putnam et al.   JOURNAL OF BACTERIOLOGY

Spo0A Differentially Regulates Toxin Production in Evolutionarily Diverse Strains of Clostridium difficile

(2013) Kate E. Mackin et al.   PLoS One

Genome-Wide Analysis of Cell Type-Specific Gene Transcription during Spore Formation in Clostridium difficile

(2013) Laure Saujet et al.   PLoS Genetics

Global Analysis of the Sporulation Pathway of Clostridium difficile

(2013) Kelly A. Fimlaid et al.   PLoS Genetics

The Spore Differentiation Pathway in the Enteric Pathogen Clostridium difficile

(2013) Fátima C. Pereira et al.   PLoS Genetics

Bile Acid Recognition by the Clostridium difficile Germinant Receptor, CspC, Is Important for Establishing Infection

(2013) Michael B. Francis et al.   PLoS Pathogens

Genomic determinants of sporulation inBacilliandClostridia: towards the minimal set of sporulation-specific genes

(2012) Michael Y. Galperin et al.   ENVIRONMENTAL MICROBIOLOGY

TheClostridium difficile spo0AGene Is a Persistence and Transmission Factor

(2012) Laura J. Deakin et al.   INFECTION AND IMMUNITY

Proline-Dependent Regulation of Clostridium difficile Stickland Metabolism

(2012) L. Bouillaut et al.   JOURNAL OF BACTERIOLOGY

Multiple Factors Modulate Biofilm Formation by the Anaerobic Pathogen Clostridium difficile

(2012) T. Thapa et al.   JOURNAL OF BACTERIOLOGY

Emergence and global spread of epidemic healthcare-associated Clostridium difficile

(2012) Miao He et al.   NATURE GENETICS

Characterisation of Clostridium difficile Biofilm Formation, a Role for Spo0A

(2012) Lisa F. Dawson et al.   PLoS One

C. difficile 630Δerm Spo0A Regulates Sporulation, but Does Not Contribute to Toxin Production, by Direct High-Affinity Binding to Target DNA

(2012) Katharina E. Rosenbusch et al.   PLoS One

Characterisation of Clostridium difficile Hospital Ward–Based Transmission Using Extensive Epidemiological Data and Molecular Typing

(2012) A. Sarah Walker et al.   PLOS MEDICINE

Targeted Restoration of the Intestinal Microbiota with a Simple, Defined Bacteriotherapy Resolves Relapsing Clostridium difficile Disease in Mice

(2012) Trevor D. Lawley et al.   PLoS Pathogens

PrsW Is Required for Colonization, Resistance to Antimicrobial Peptides, and Expression of Extracytoplasmic Function σ Factors in Clostridium difficile

(2011) Theresa D. Ho et al.   INFECTION AND IMMUNITY

Surface Layers of Clostridium difficile Endospores

(2011) P. Permpoonpattana et al.   JOURNAL OF BACTERIOLOGY

Sporicides for Clostridium difficile: the devil is in the detail

(2011) M.H. Wilcox et al.   JOURNAL OF HOSPITAL INFECTION

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Identification of a Genetic Locus Responsible for Antimicrobial Peptide Resistance inClostridium difficile

(2010) Shonna M. McBride et al.   INFECTION AND IMMUNITY

Integration of Metabolism and Virulence by Clostridium difficile CodY

(2010) S. S. Dineen et al.   JOURNAL OF BACTERIOLOGY

Clostridium difficile PCR ribotype 027: assessing the risks of further worldwide spread

(2010) Archie CA Clements et al.   LANCET INFECTIOUS DISEASES

CcpA-mediated repression of Clostridium difficile toxin gene expression

(2010) Ana Antunes et al.   MOLECULAR MICROBIOLOGY

Evolutionary dynamics of Clostridium difficile over short and long time scales

(2010) M. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broadly heterogeneous activation of the master regulator for sporulation in Bacillus subtilis

(2010) A. Chastanet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

A mariner-Based Transposon System for In Vivo Random Mutagenesis of Clostridium difficile

(2009) S. T. Cartman et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Antibiotic Treatment of Clostridium difficile Carrier Mice Triggers a Supershedder State, Spore-Mediated Transmission, and Severe Disease in Immunocompromised Hosts

(2009) T. D. Lawley et al.   INFECTION AND IMMUNITY

Characterization of the Sporulation Initiation Pathway of Clostridium difficile and Its Role in Toxin Production

(2009) S. Underwood et al.   JOURNAL OF BACTERIOLOGY

Motility and Flagellar Glycosylation in Clostridium difficile

(2009) S. M. Twine et al.   JOURNAL OF BACTERIOLOGY

Proteomic and Genomic Characterization of Highly Infectious Clostridium difficile 630 Spores

(2009) T. D. Lawley et al.   JOURNAL OF BACTERIOLOGY

A simple method for directional transcriptome sequencing using Illumina technology

(2009) N. J. Croucher et al.   NUCLEIC ACIDS RESEARCH

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

(2009) Richard A Stabler et al.   GENOME BIOLOGY

A Mouse Model of Clostridium difficile–Associated Disease

(2008) Xinhua Chen et al.   GASTROENTEROLOGY

Decreased Diversity of the Fecal Microbiome in RecurrentClostridium difficile–Associated Diarrhea

(2008) Ju Young Chang et al.   JOURNAL OF INFECTIOUS DISEASES

Triplex protein quantification based on stable isotope labeling by peptide dimethylation applied to cell and tissue lysates

(2008) Paul J. Boersema et al.   PROTEOMICS