Comprehensive insights into transcriptional adaptation of intracellular mycobacteria by microbe-enriched dual RNA sequencing

Integration of heterogeneous molecular networks to unravel gene-regulation in Mycobacterium tuberculosis

(2014) Jesse CJ van Dam et al.   BMC Systems Biology

Mycolic Acids: Structures, Biosynthesis, and Beyond

(2014) Hedia Marrakchi et al.   CHEMISTRY & BIOLOGY

Pathogen roid rage: Cholesterol utilization byMycobacterium tuberculosis

(2014) Matthew F. Wipperman et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Systems-level modeling of mycobacterial metabolism for the identification of new (multi-)drug targets

(2014) Rienk A. Rienksma et al.   SEMINARS IN IMMUNOLOGY

Global Adaptation to a Lipid Environment Triggers the Dormancy-Related Phenotype of Mycobacterium tuberculosis

(2014) J. G. Rodriguez et al.   mBio

Mycobacterium tuberculosis Exploits Asparagine to Assimilate Nitrogen and Resist Acid Stress during Infection

(2014) Alexandre Gouzy et al.   PLoS Pathogens

Mycobacterium tuberculosis Utilizes a Unique Heterotetrameric Structure for Dehydrogenation of the Cholesterol Side Chain

(2013) Suzanne T. Thomas et al.   BIOCHEMISTRY

Host-Mycobacterium avium subsp. paratuberculosis interactome reveals a novel iron assimilation mechanism linked to nitric oxide stress during early infection

(2013) Elise A Lamont et al.   BMC GENOMICS

Heme Catabolism by Heme Oxygenase-1 Confers Host Resistance to Mycobacterium Infection

(2013) Sandro Silva-Gomes et al.   INFECTION AND IMMUNITY

Shrinking the FadE Proteome of Mycobacterium tuberculosis: Insights into Cholesterol Metabolism through Identification of an  2 2 Heterotetrameric Acyl Coenzyme A Dehydrogenase Family

(2013) M. F. Wipperman et al.   JOURNAL OF BACTERIOLOGY

Mycobacterium tuberculosis Cholesterol Catabolism Requires a New Class of Acyl Coenzyme A Dehydrogenase

(2013) M. I. Voskuil   JOURNAL OF BACTERIOLOGY

Cutting Edge: Mycobacterium tuberculosis but Not Nonvirulent Mycobacteria Inhibits IFN-  and AIM2 Inflammasome-Dependent IL-1  Production via Its ESX-1 Secretion System

(2013) S. Shah et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis nitrogen assimilation and host colonization require aspartate

(2013) Alexandre Gouzy et al.   Nature Chemical Biology

A Gene Expression Study of the Activities of Aromatic Ring-Cleavage Dioxygenases in Mycobacterium gilvum PYR-GCK to Changes in Salinity and pH during Pyrene Degradation

(2013) Abimbola Comfort Badejo et al.   PLoS One

Identification of Novel sRNAs in Mycobacterial Species

(2013) Chen-Hsun Tsai et al.   PLoS One

Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis

(2013) Ryan M. Wells et al.   PLoS Pathogens

Intracellular Bacillary Burden Reflects a Burst Size for Mycobacterium tuberculosis In Vivo

(2013) Teresa Repasy et al.   PLoS Pathogens

A central role for aspartate in Mycobacterium tuberculosis physiology and virulence

(2013) Alexandre Gouzy et al.   Frontiers in Cellular and Infection Microbiology

Mycobacterium tuberculosis-Driven Targeted Recalibration of Macrophage Lipid Homeostasis Promotes the Foamy Phenotype

(2012) Varshneya Singh et al.   Cell Host & Microbe

Cholesterol Catabolism by Mycobacterium tuberculosis Requires Transcriptional and Metabolic Adaptations

(2012) Jennifer E. Griffin et al.   CHEMISTRY & BIOLOGY

Analyses of MbtB, MbtE, and MbtF Suggest Revisions to the Mycobactin Biosynthesis Pathway in Mycobacterium tuberculosis

(2012) M. D. McMahon et al.   JOURNAL OF BACTERIOLOGY

ChoD and HsdD can be dispensable for cholesterol degradation in mycobacteria

(2012) Anna Brzostek et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation

(2012) Daria Bottai et al.   MOLECULAR MICROBIOLOGY

FadD3 is an acyl-CoA synthetase that initiates catabolism of cholesterol rings C and D in actinobacteria

(2012) Israël Casabon et al.   MOLECULAR MICROBIOLOGY

Dual RNA-seq of pathogen and host

(2012) Alexander J. Westermann et al.   NATURE REVIEWS MICROBIOLOGY

BSRD: a repository for bacterial small regulatory RNA

(2012) Lei Li et al.   NUCLEIC ACIDS RESEARCH

Non-coding RNA and its potential role in Mycobacterium tuberculosis pathogenesis

(2012) Kristine Arnvig et al.   RNA Biology

Efficient and robust RNA-seq process for cultured bacteria and complex community transcriptomes

(2012) Georgia Giannoukos et al.   GENOME BIOLOGY

Structural Features in the KshA Terminal Oxygenase Protein That Determine Substrate Preference of 3-Ketosteroid 9 -Hydroxylase Enzymes

(2011) M. Petrusma et al.   JOURNAL OF BACTERIOLOGY

Bacterial proteins with cleaved or uncleaved signal peptides of the general secretory pathway

(2011) Gustavo A. de Souza et al.   Journal of Proteomics

Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis

(2011) Hugues Ouellet et al.   TRENDS IN MICROBIOLOGY

The Steroid Catabolic Pathway of the Intracellular Pathogen Rhodococcus equi Is Important for Pathogenesis and a Target for Vaccine Development

(2011) R. van der Geize et al.   PLoS Pathogens

Sequence-Based Analysis Uncovers an Abundance of Non-Coding RNA in the Total Transcriptome of Mycobacterium tuberculosis

(2011) Kristine B. Arnvig et al.   PLoS Pathogens

Structural and Biochemical Characterization ofMycobacterium tuberculosisCYP142

(2010) Max D. Driscoll et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators: kstR and kstR2

(2010) S. L. Kendall et al.   MICROBIOLOGY-SGM

NAD+auxotrophy is bacteriocidal for the tubercle bacilli

(2010) Catherine Vilchèze et al.   MOLECULAR MICROBIOLOGY

Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one

(2010) Hugues Ouellet et al.   MOLECULAR MICROBIOLOGY

Multiple small RNAs identified in Mycobacterium bovis BCG are also expressed in Mycobacterium tuberculosis and Mycobacterium smegmatis

(2010) J. M. DiChiara et al.   NUCLEIC ACIDS RESEARCH

Bacterial/archaeal/organellar polyadenylation

(2010) Bijoy K. Mohanty et al.   Wiley Interdisciplinary Reviews-RNA

Direct sequencing of the human microbiome readily reveals community differences

(2010) Justin Kuczynski et al.   GENOME BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Deep RNA sequencing of L. monocytogenes reveals overlapping and extensive stationary phase and sigma B-dependent transcriptomes, including multiple highly transcribed noncoding RNAs

(2009) Haley F Oliver et al.   BMC GENOMICS

Unique Roles of DosT and DosS in DosR Regulon Induction and Mycobacterium tuberculosis Dormancy

(2009) R. W. Honaker et al.   INFECTION AND IMMUNITY

The Mycobacterium tuberculosis High-Affinity Iron Importer, IrtA, Contains an FAD-Binding Domain

(2009) M. B. Ryndak et al.   JOURNAL OF BACTERIOLOGY

igr Genes and Mycobacterium tuberculosis Cholesterol Metabolism

(2009) J. C. Chang et al.   JOURNAL OF BACTERIOLOGY

A Novel In Vitro Multiple-Stress Dormancy Model for Mycobacterium tuberculosis Generates a Lipid-Loaded, Drug-Tolerant, Dormant Pathogen

(2009) Chirajyoti Deb et al.   PLoS One

Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition

(2009) M. S. Siegrist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping the Burkholderia cenocepacia niche response via high-throughput sequencing

(2009) D. R. Yoder-Himes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Strand-Specific RNA–Seq Analysis of the Transcriptome of the Typhoid Bacillus Salmonella Typhi

(2009) Timothy T. Perkins et al.   PLoS Genetics

Studies of a Ring-Cleaving Dioxygenase Illuminate the Role of Cholesterol Metabolism in the Pathogenesis of Mycobacterium tuberculosis

(2009) Katherine C. Yam et al.   PLoS Pathogens

Systematic Genetic Nomenclature for Type VII Secretion Systems

(2009) Wilbert Bitter et al.   PLoS Pathogens

Mycobacterium tuberculosisexpresses methionine sulphoxide reductases A and B that protect from killing by nitrite and hypochlorite

(2008) Warren L. Lee et al.   MOLECULAR MICROBIOLOGY

InnateDB: facilitating systems-level analyses of the mammalian innate immune response

(2008) David J Lynn et al.   Molecular Systems Biology

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The rpoB gene as a tool for clinical microbiologists

(2008) Toïdi Adékambi et al.   TRENDS IN MICROBIOLOGY