Collaborative Cross mice reveal extreme epilepsy phenotypes and genetic loci for seizure susceptibility

Identification of a Functional Non-coding Variant in the GABAA Receptor α2 Subunit of the C57BL/6J Mouse Reference Genome: Major Implications for Neuroscience Research

(2019) Megan K. Mulligan et al.   Frontiers in Genetics

Diverse tumour susceptibility in Collaborative Cross mice: identification of a new mouse model for human gastric tumourigenesis

(2019) Pin Wang et al.   GUT

Novel GABRA2 variants in epileptic encephalopathy and intellectual disability with seizures

(2019) Snezana Maljevic et al.   BRAIN

The Collaborative Cross: A Systems Genetics Resource for Studying Host-Pathogen Interactions

(2019) Kelsey E. Noll et al.   Cell Host & Microbe

Potentiating α 2 subunit containing perisomatic GABA A receptors protects against seizures in a mouse model of Dravet syndrome

(2019) Toshihiro Nomura et al.   JOURNAL OF PHYSIOLOGY-LONDON

Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures

(2019) Anna J. Nathanson et al.   Cell Reports

De novo variants in GABRA2 and GABRA5 alter receptor function and contribute to early-onset epilepsy

(2018) Kameryn M Butler et al.   BRAIN

A de novo GABRA2 missense mutation in severe early-onset epileptic encephalopathy with a choreiform movement disorder

(2018) Naama Orenstein et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multi-parent Populations

(2018) Karl W. Broman et al.   GENETICS

Ube3a reinstatement mitigates epileptogenesis in Angelman syndrome model mice

(2018) Bin Gu et al.   JOURNAL OF CLINICAL INVESTIGATION

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

(2018)   Nature Communications

Modeling the quantitative nature of neurodevelopmental disorders using Collaborative Cross mice

(2018) Remco T. Molenhuis et al.   Molecular Autism

Perinatal nutrition interacts with genetic background to alter behavior in a parent-of-origin-dependent manner in adult Collaborative Cross mice

(2017) S. A. Schoenrock et al.   GENES BRAIN AND BEHAVIOR

Genomes of the Mouse Collaborative Cross

(2017) Anuj Srivastava et al.   GENETICS

Genomes of the Mouse Collaborative Cross

(2017) Anuj Srivastava et al.   GENETICS

Sudden unexpected death in epilepsy genetics: Molecular diagnostics and prevention

(2016) Alica M. Goldman et al.   EPILEPSIA

Prevalence and incidence of epilepsy

(2016) Kirsten M. Fiest et al.   NEUROLOGY

Fine Mapping of a Dravet Syndrome Modifier Locus on Mouse Chromosome 5 and Candidate Gene Analysis by RNA-Seq

(2016) Nicole A. Hawkins et al.   PLoS Genetics

Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database

(2015) Molly A. Bogue et al.   MAMMALIAN GENOME

Marker-Based Estimation of Heritability in Immortal Populations

(2014) Willem Kruijer et al.   GENETICS

Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies

(2014)   LANCET NEUROLOGY

Segregation of Seizure Traits in C57 Black Mouse Substrains Using the Repeated-Flurothyl Model

(2014) Sridhar B. Kadiyala et al.   PLoS One

New avenues for anti-epileptic drug discovery and development

(2013) Wolfgang Löscher et al.   NATURE REVIEWS DRUG DISCOVERY

Mechanisms of epileptogenesis: a convergence on neural circuit dysfunction

(2013) Ethan M. Goldberg et al.   NATURE REVIEWS NEUROSCIENCE

Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32

(2012) et al.   HUMAN MOLECULAR GENETICS

Sudden, Unexpected Death in Epilepsy

(2011) Orrin Devinsky   NEW ENGLAND JOURNAL OF MEDICINE

Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study

(2010) Dalia Kasperavičiūtė et al.   BRAIN

DBA/1 mice exhibit chronic susceptibility to audiogenic seizures followed by sudden death associated with respiratory arrest

(2010) Carl L. Faingold et al.   EPILEPSY & BEHAVIOR

Analysis of flurothyl-induced myoclonus in inbred strains of mice

(2009) Dominick Papandrea et al.   EPILEPSY RESEARCH

Dissociation of seizure traits in inbred strains of mice using the flurothyl kindling model of epileptogenesis

(2008) Dominick Papandrea et al.   EXPERIMENTAL NEUROLOGY