Iron loss triggers mitophagy through induction of mitochondrial ferritin

Mitophagy and Neuroprotection

(2019) Guofeng Lou et al.   TRENDS IN MOLECULAR MEDICINE

Mitochondria—Striking a balance between host and endosymbiont

(2019) Richard J. Youle   SCIENCE

PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol

(2018) Shiori Sekine et al.   BMC BIOLOGY

Mechanisms of mitophagy in cellular homeostasis, physiology and pathology

(2018) Konstantinos Palikaras et al.   NATURE CELL BIOLOGY

The Role of Deferiprone in Iron Chelation

(2018) Robert C. Hider et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cytosolic BNIP3 Dimer Interacts with Mitochondrial BAX Forming Heterodimers in the Mitochondrial Outer Membrane under Basal Conditions

(2017) Ulrike Hendgen-Cotta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Parkin-Independent Mitophagy Controls Chemotherapeutic Response in Cancer Cells

(2017) Elodie Villa et al.   Cell Reports

The PINK1, synphilin-1 and SIAH-1 complex constitutes a novel mitophagy pathway

(2016) Raymonde Szargel et al.   HUMAN MOLECULAR GENETICS

mito-QC illuminates mitophagy and mitochondrial architecture in vivo

(2016) Thomas G. McWilliams et al.   JOURNAL OF CELL BIOLOGY

Mechanisms of Selective Autophagy

(2016) Gabriele Zaffagnini et al.   JOURNAL OF MOLECULAR BIOLOGY

Ubiquitin-Dependent And Independent Signals In Selective Autophagy

(2016) Aliaksandr Khaminets et al.   TRENDS IN CELL BIOLOGY

Characterization of human mitochondrial ferritin promoter: identification of transcription factors and evidences of epigenetic control

(2016) Michela Guaraldo et al.   Scientific Reports

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation

(2015) Tomokazu Murakawa et al.   Nature Communications

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis

(2015) Joseph D Mancias et al.   eLife

Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation

(2014) Zhen-Hua Shi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Branched-chain amino acids reduce hepatic iron accumulation and oxidative stress in hepatitis C virus polyprotein-expressing mice

(2014) Masaaki Korenaga et al.   LIVER INTERNATIONAL

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Loss of iron triggers PINK1/Parkin-independent mitophagy

(2013) George F G Allen et al.   EMBO REPORTS

A murine model for non-alcoholic steatohepatitis showing evidence of association between diabetes and hepatocellular carcinoma

(2013) Masato Fujii et al.   Medical Molecular Morphology

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase

(2013) Min Fu et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

(2013) Yoshinobu Ichimura et al.   MOLECULAR CELL

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

(2013) Samuel A. Hasson et al.   NATURE

Iron Deprivation in Cancer––Potential Therapeutic Implications

(2013) Jessica Heath et al.   Nutrients

Transcriptional regulation of specific protein 1 (SP1) by hypoxia-inducible factor 1 alpha (HIF-1α) leads to PRNP expression and neuroprotection from toxic prion peptide

(2012) Jae-Kyo Jeong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RETRACTED: The Ubiquitin Ligase Mul1 Induces Mitophagy in Skeletal Muscle in Response to Muscle-Wasting Stimuli

(2012) Sudarsanareddy Lokireddy et al.   Cell Metabolism

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

(2012) Lei Liu et al.   NATURE CELL BIOLOGY

Characterization of macroautophagic flux in vivo using a leupeptin-based assay

(2011) Jeffrey Haspel et al.   Autophagy

Induction of hypoxia inducible factor (HIF-1α) in rat kidneys by iron chelation with the hydroxypyridinone, CP94

(2011) Jin Hyen Baek et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

A Sensitive and Quantitative Technique for Detecting Autophagic Events Based on Lysosomal Delivery

(2011) Hiroyuki Katayama et al.   CHEMISTRY & BIOLOGY

Autophagy-deficient mice develop multiple liver tumors

(2011) A. Takamura et al.   GENES & DEVELOPMENT

Mitophagy Plays an Essential Role in Reducing Mitochondrial Production of Reactive Oxygen Species and Mutation of Mitochondrial DNA by Maintaining Mitochondrial Quantity and Quality in Yeast

(2011) Yusuke Kurihara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Image-based genome-wide siRNA screen identifies selective autophagy factors

(2011) Anthony Orvedahl et al.   NATURE

Deferoxamine for Advanced Hepatocellular Carcinoma

(2011) Takahiro Yamasaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bnip3-mediated mitochondrial autophagy is independent of the mitochondrial permeability transition pore

(2010) Melissa N. Quinsay et al.   Autophagy

Retromer-mediated direct sorting is required for proper endosomal recycling of the mammalian iron transporter DMT1

(2010) M. Tabuchi et al.   JOURNAL OF CELL SCIENCE

Importing Mitochondrial Proteins: Machineries and Mechanisms

(2009) Agnieszka Chacinska et al.   CELL

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

(2008) P. K. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis C Virus–Induced Reactive Oxygen Species Raise Hepatic Iron Level in Mice by Reducing Hepcidin Transcription

(2007) Sohji Nishina et al.   GASTROENTEROLOGY