A hairy tale: SIRT 7 safeguards skin stem cells during aging

SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer

(2020) Shijia Bi et al.   Protein & Cell

SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair

(2019) Ming Tang et al.   Science Advances

LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation

(2019) Matthew Simon et al.   Cell Metabolism

SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina

(2019) Berta N Vazquez et al.   NUCLEIC ACIDS RESEARCH

The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability

(2018) Silvana Paredes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT7 promotes genome integrity and modulates non‐homologous end joining DNA repair

(2016) Berta N Vazquez et al.   EMBO JOURNAL

Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis

(2016) H. Matsumura et al.   SCIENCE

SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing

(2016) Sifan Chen et al.   Nature Communications

A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging

(2015) M. Mohrin et al.   SCIENCE

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

(2012) Matthew F. Barber et al.   NATURE

SIRT6 Promotes DNA Repair Under Stress by Activating PARP1

(2011) Z. Mao et al.   SCIENCE