HIV ‐1 capsids mimic a microtubule regulator to coordinate early stages of infection

Capsid labelled HIV to investigate the role of capsid during nuclear import and integration

(2020) Irena Zurnic Bönisch et al.   JOURNAL OF VIROLOGY

HIV-1 uncoats in the nucleus near sites of integration

(2020) Ryan C. Burdick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of HIV-1 uncoating in human microglial cell lines

(2020) Zachary Ingram et al.   Virology Journal

HIV-1 exploits CLASP2 to induce microtubule stabilization and facilitate virus trafficking to the nucleus

(2020) Sahana Mitra et al.   JOURNAL OF VIROLOGY

Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes

(2020) Guillermo Blanco-Rodriguez et al.   JOURNAL OF VIROLOGY

Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus

(2020) Adarsh Dharan et al.   Nature Microbiology

HIV-1 nuclear import in macrophages is regulated by CPSF6-capsid interactions at the Nuclear Pore Complex

(2019) David Alejandro Bejarano et al.   eLife

Novel Intersubunit Interaction Critical for HIV-1 Core Assembly Defines a Potentially Targetable Inhibitor Binding Pocket

(2019) Pierrick Craveur et al.   mBio

Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms

(2019) Brady J. Summers et al.   Cell Host & Microbe

Analysis of CA Content and CPSF6 Dependence of Early HIV-1 Replication Complexes in SupT1-R5 Cells

(2019) Vojtech Zila et al.   mBio

Transportin-1 binds to the HIV-1 capsid via a nuclear localization signal and triggers uncoating

(2019) Juliette Fernandez et al.   Nature Microbiology

Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport

(2018) Ashwanth C. Francis et al.   Cell Host & Microbe

The HCMV Assembly Compartment Is a Dynamic Golgi-Derived MTOC that Controls Nuclear Rotation and Virus Spread

(2018) Dean J. Procter et al.   DEVELOPMENTAL CELL

The cytoplasmic dynein transport machinery and its many cargoes

(2018) Samara L. Reck-Peterson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis

(2018) Chantal L Márquez et al.   eLife

Mapping multivalency in the CLIP-170–EB1 microtubule plus-end complex

(2018) Yaodong Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microtubule Regulation and Function during Virus Infection

(2017) Mojgan H. Naghavi et al.   JOURNAL OF VIROLOGY

Tubulin acetylation protects long-lived microtubules against mechanical ageing

(2017) Didier Portran et al.   NATURE CELL BIOLOGY

Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport

(2017) Michael Keegan Delaney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early cytoplasmic uncoating is associated with infectivity of HIV-1

(2017) João I. Mamede et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microtubules acquire resistance from mechanical breakage through intralumenal acetylation

(2017) Zhenjie Xu et al.   SCIENCE

Microtubule plus-end tracking proteins in neuronal development

(2016) Dieudonnée van de Willige et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

HIV-1 capsid is involved in post-nuclear entry steps

(2016) Nan-Yu Chen et al.   Retrovirology

Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site

(2016) Chuang Liu et al.   Nature Communications

Microtubule plus end–associated CLIP-170 initiates HSV-1 retrograde transport in primary human cells

(2015) Vladimir Jovasevic et al.   JOURNAL OF CELL BIOLOGY

Mutations of Conserved Residues in the Major Homology Region Arrest Assembling HIV-1 Gag as a Membrane-Targeted Intermediate Containing Genomic RNA and Cellular Proteins

(2015) Motoko Tanaka et al.   JOURNAL OF VIROLOGY

Human Immunodeficiency Virus Type 1 Employs the Cellular Dynein Light Chain 1 Protein for Reverse Transcription through Interaction with Its Integrase Protein

(2015) Kallesh Danappa Jayappa et al.   JOURNAL OF VIROLOGY

HIV-1 capsid: the multifaceted key player in HIV-1 infection

(2015) Edward M. Campbell et al.   NATURE REVIEWS MICROBIOLOGY

Control of microtubule organization and dynamics: two ends in the limelight

(2015) Anna Akhmanova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus

(2015) Viacheslav Malikov et al.   Nature Communications

HIV-1 Entry in SupT1-R5, CEM-ss, and Primary CD4+ T Cells Occurs at the Plasma Membrane and Does Not Require Endocytosis

(2014) N. Herold et al.   JOURNAL OF VIROLOGY

Identification of Capsid Mutations That Alter the Rate of HIV-1 Uncoating in Infected Cells

(2014) Amy E. Hulme et al.   JOURNAL OF VIROLOGY

HIV-1 Uncoating Is Facilitated by Dynein and Kinesin 1

(2014) Z. Lukic et al.   JOURNAL OF VIROLOGY

Reconstitution of a hierarchical +TIP interaction network controlling microtubule end tracking of dynein

(2014) Christian Duellberg et al.   NATURE CELL BIOLOGY

HIV-1 uncoating: connection to nuclear entry and regulation by host proteins

(2014) Zandrea Ambrose et al.   VIROLOGY

Cytoplasmic Dynein Promotes HIV-1 Uncoating

(2014) Paulina Pawlica et al.   Viruses-Basel

Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid

(2014) Ke Peng et al.   eLife

HIV-1 Induces the Formation of Stable Microtubules to Enhance Early Infection

(2013) Yosef Sabo et al.   Cell Host & Microbe

HIV-1 evades innate immune recognition through specific cofactor recruitment

(2013) Jane Rasaiyaah et al.   NATURE

A Proteome-wide Screen for Mammalian SxIP Motif-Containing Microtubule Plus-End Tracking Proteins

(2012) Kai Jiang et al.   CURRENT BIOLOGY

Differential Effects of Human Immunodeficiency Virus Type 1 Capsid and Cellular Factors Nucleoporin 153 and LEDGF/p75 on the Efficiency and Specificity of Viral DNA Integration

(2012) Y. Koh et al.   JOURNAL OF VIROLOGY

Coupling viruses to dynein and kinesin-1

(2011) Mark P Dodding et al.   EMBO JOURNAL

Interaction of mammalian end binding proteins with CAP-Gly domains of CLIP-170 and p150glued

(2011) Saša Bjelić et al.   JOURNAL OF STRUCTURAL BIOLOGY

Atomic-level modelling of the HIV capsid

(2011) Owen Pornillos et al.   NATURE

Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions

(2011) Carsten Janke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

Transportin 3 Promotes a Nuclear Maturation Step Required for Efficient HIV-1 Integration

(2011) Lihong Zhou et al.   PLoS Pathogens

Plus-End-Tracking Proteins and Their Interactions at Microtubule Ends

(2010) Niels Galjart   CURRENT BIOLOGY

Microtubule tip-interacting proteins: a view from both ends

(2010) Kai Jiang et al.   CURRENT OPINION IN CELL BIOLOGY

X-Ray Structures of the Hexameric Building Block of the HIV Capsid

(2009) Owen Pornillos et al.   CELL

HIV Enters Cells via Endocytosis and Dynamin-Dependent Fusion with Endosomes

(2009) Kosuke Miyauchi et al.   CELL

An EB1-Binding Motif Acts as a Microtubule Tip Localization Signal

(2009) Srinivas Honnappa et al.   CELL

Characterization of the In Vitro HIV-1 Capsid Assembly Pathway

(2009) Eric Barklis et al.   JOURNAL OF MOLECULAR BIOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Tracking the ends: a dynamic protein network controls the fate of microtubule tips

(2008) Anna Akhmanova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY