Phytochemical conjugation as a potential semisynthetic approach toward reactive and reuse of obsolete sulfonamides against pathogenic bacteria

Semisynthetic and newly designed derivatives based on natural chemical scaffolds: moving beyond natural products to fight Trypanosoma cruzi

(2020) Rafael da Rosa et al.   PHYTOCHEMISTRY REVIEWS

Isoniazid–phytochemical conjugation: A new approach for potent and less toxic anti‐TB drug development

(2020) Shasank S. Swain et al.   Chemical Biology & Drug Design

Computer-aided synthesis of dapsone-phytochemical conjugates against dapsone-resistant Mycobacterium leprae

(2020) Shasank S. Swain et al.   Scientific Reports

Antioxidant and antibacterial activity of seven predominant terpenoids

(2019) Chung-Yi Wang et al.   INTERNATIONAL JOURNAL OF FOOD PROPERTIES

Exploring Dittrichia viscosa (L.) Greuter phytochemical diversity to explain its antimicrobial, nematicidal and insecticidal activity

(2019) Laura Grauso et al.   PHYTOCHEMISTRY REVIEWS

Sulfonamide derivatives as multi-target agents for complex diseases

(2019) Sinem Apaydın et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Novel Antimicrobial–Phytochemical Conjugate With Antimicrobial Activity Against Streptococcus uberis, Enterococcus faecium, and Enterococcus faecalis

(2019) Karthic Rajamanickam et al.   Frontiers in Pharmacology

Molecular modeling, synthesis, antibacterial and cytotoxicity evaluation of sulfonamide derivatives of benzimidazole, indazole, benzothiazole and thiazole

(2018) Farha Naaz et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Sulfonamide inhibitors: a patent review 2013-present

(2018) İlhami Gulçin et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Discovery and development of new antibacterial drugs: learning from experience?

(2018) Nicole Jackson et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Synthesis of novel thymol derivatives against MRSA and ESBL producing pathogenic bacteria

(2018) Shasank S. Swain et al.   NATURAL PRODUCT RESEARCH

Synergistic combination of two antimicrobial agents closing each other’s mutant selection windows to prevent antimicrobial resistance

(2018) Xuejie Xu et al.   Scientific Reports

Review of Treatment of Gunshot Wounds to Head in Late 19th Century

(2018) Matthew Protas et al.   World Neurosurgery

Synergy between conventional antibiotics and anti-biofilm peptides in a murine, sub-cutaneous abscess model caused by recalcitrant ESKAPE pathogens

(2018) Daniel Pletzer et al.   PLoS Pathogens

The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations in Staphylococcus aureus Dihydropteroate Synthase

(2018) Elizabeth C. Griffith et al.   Frontiers in Microbiology

Mobile Genetic Elements Associated with Antimicrobial Resistance

(2018) Sally R. Partridge et al.   CLINICAL MICROBIOLOGY REVIEWS

Molecular docking and simulation study for synthesis of alternative dapsone derivative as a newer antileprosy drug in multidrug therapy

(2018) Shasank S. Swain et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Current Screening Methodologies in Drug Discovery for Selected Human Diseases

(2018) Olga Lage et al.   Marine Drugs

Phytochemicals for human disease: An update on plant-derived compounds antibacterial activity

(2017) Ramona Barbieri et al.   MICROBIOLOGICAL RESEARCH

Novel Sulfamethoxazole Ureas and Oxalamide as Potential Antimycobacterial Agents

(2017) Martin Krátký et al.   MOLECULES

Sulfadiazine Salicylaldehyde-Based Schiff Bases: Synthesis, Antimicrobial Activity and Cytotoxicity

(2017) Martin Krátký et al.   MOLECULES

Phytochemicals from fern species: potential for medicine applications

(2017) Hui Cao et al.   PHYTOCHEMISTRY REVIEWS

Improving Drug Design: An Update on Recent Applications of Efficiency Metrics, Strategies for Replacing Problematic Elements, and Compounds in Nontraditional Drug Space

(2016) Nicholas A. Meanwell   CHEMICAL RESEARCH IN TOXICOLOGY

The structural modification of natural products for novel drug discovery

(2016) Hong Yao et al.   Expert Opinion on Drug Discovery

Investigational protease inhibitors as antiretroviral therapies

(2016) Narasimha M. Midde et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Synthesis of novel sulfonamides under mild conditions with effective inhibitory activity against the carbonic anhydrase isoforms I and II

(2016) Erhan Başar et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

New series of aromatic/ five-membered heteroaromatic butanesulfonyl hydrazones as potent biological agents: Synthesis, physicochemical and electronic properties

(2016) Fatma Hamurcu et al.   JOURNAL OF MOLECULAR STRUCTURE

Discovery of a potential lead compound for treating leprosy with dapsone resistance mutation in M. leprae folP1

(2016) J. Nisha et al.   Molecular BioSystems

Natural Products as a Source for Novel Antibiotics

(2016) Mark G. Moloney   TRENDS IN PHARMACOLOGICAL SCIENCES

Antimicrobial resistance—a threat to the world’s sustainable development

(2016) Dušan Jasovský et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

Will 10 Million People Die a Year due to Antimicrobial Resistance by 2050?

(2016) Marlieke E. A. de Kraker et al.   PLOS MEDICINE

Evolution and Diversity of the Antimicrobial Resistance Associated Mobilome in Streptococcus suis: A Probable Mobile Genetic Elements Reservoir for Other Streptococci

(2016) Jinhu Huang et al.   Frontiers in Cellular and Infection Microbiology

Discovery and resupply of pharmacologically active plant-derived natural products: A review

(2015) Atanas G. Atanasov et al.   BIOTECHNOLOGY ADVANCES

Synthesis and antimicrobial activity of sulphamethoxazole-based ureas and imidazolidine-2,4,5-triones

(2015) Martin Krátký et al.   CHEMICAL PAPERS

Antimicrobial interactions: mechanisms and implications for drug discovery and resistance evolution

(2015) Tobias Bollenbach   CURRENT OPINION IN MICROBIOLOGY

Antibiotics, Bacteria, and Antibiotic Resistance Genes: Aerial Transport from Cattle Feed Yards via Particulate Matter

(2015) Andrew D. McEachran et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Insights into drug discovery from natural products through structural modification

(2015) Jichao Chen et al.   FITOTERAPIA

Solvent-free synthesis of novel styrenesulfonamide derivatives and evaluation of their antibacterial activity

(2015) Narjes Khaton Maghsoodi et al.   JOURNAL OF CHEMICAL RESEARCH

Is ayurveda the key to universal healthcare in India?

(2015) N. Bhandari   BMJ-British Medical Journal

Is ayurveda the key to universal healthcare in India?

(2015) N. Bhandari   BMJ-British Medical Journal

Repurposing Clinical Molecule Ebselen to Combat Drug Resistant Pathogens

(2015) Shankar Thangamani et al.   PLoS One

N-Acylated Derivatives of Sulfamethoxazole and Sulfafurazole Inhibit Intracellular Growth of Chlamydia trachomatis

(2014) S. Marwaha et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibacterial Activity of Sulfamethoxazole Transformation Products (TPs): General Relevance for Sulfonamide TPs Modified at the para Position

(2014) Marius Majewsky et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Synthesis and antibacterial activity of sulfonamides. SAR and DFT studies

(2014) Wahida Boufas et al.   JOURNAL OF MOLECULAR STRUCTURE

Antibacterial and Antioxidant Activity of Essential Oil Terpenes against Pathogenic and Spoilage-Forming Bacteria and Cell Structure-Activity Relationships Evaluated by SEM Microscopy

(2014) Hatice Zengin et al.   MOLECULES

Natural products: A continuing source of novel drug leads

(2013) Gordon M. Cragg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Biological activity, design, synthesis and structure activity relationship of some novel derivatives of curcumin containing sulfonamides

(2013) Jaggi Lal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Sulfa and trimethoprim-like drugs – antimetabolites acting as carbonic anhydrase, dihydropteroate synthase and dihydrofolate reductase inhibitors

(2013) Clemente Capasso et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Antibiotic resistance—the need for global solutions

(2013) Ramanan Laxminarayan et al.   LANCET INFECTIOUS DISEASES

Methods for site-specific drug conjugation to antibodies

(2013) Christopher R Behrens et al.   mAbs

Antibacterial Activity of Salicylanilide 4-(Trifluoromethyl)-benzoates

(2013) Martin Krátký et al.   MOLECULES

Combination approaches to combat multidrug-resistant bacteria

(2013) Roberta J. Worthington et al.   TRENDS IN BIOTECHNOLOGY

Synergistic effect of clinically used antibiotics and peptide antibiotics against Gram-positive and Gram-negative bacteria

(2013) YULING ZHOU et al.   Experimental and Therapeutic Medicine

Molecular Property Filters Describing Pharmacokinetics and Drug Binding

(2012) A. T. Garcia-Sosa et al.   CURRENT MEDICINAL CHEMISTRY

Antimicrobial activity of sulfonamides containing 5-chloro-2-hydroxybenzaldehyde and 5-chloro-2-hydroxybenzoic acid scaffold

(2012) Martin Krátký et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The 2012 Garrod Lecture: Discovery of antibacterial drugs in the 21st century

(2012) I. Chopra   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Future development of global regulations of Chinese herbal products

(2012) Tai-Ping Fan et al.   JOURNAL OF ETHNOPHARMACOLOGY

Plants as sources of new antimicrobials and resistance-modifying agents

(2012) Ana Cristina Abreu et al.   NATURAL PRODUCT REPORTS

Catalysis and Sulfa Drug Resistance in Dihydropteroate Synthase

(2012) M.-K. Yun et al.   SCIENCE

The antibacterial activity of some sulfonamides and sulfonyl hydrazones, and 2D-QSAR study of a series of sulfonyl hydrazones

(2012) H. Güzin Aslan et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Impact of Drug Conjugation on Pharmacokinetics and Tissue Distribution of Anti-STEAP1 Antibody–Drug Conjugates in Rats

(2011) C. Andrew Boswell et al.   BIOCONJUGATE CHEMISTRY

Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1

(2011) Elisabeth-Maria Bissinger et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Natural products: An evolving role in future drug discovery

(2011) Bhuwan B. Mishra et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Drug repositioning in the treatment of malaria and TB

(2011) Alexis Nzila et al.   Future Medicinal Chemistry

Synthesis, characterization and biological studies of sulfonamide Schiff’s bases and some of their metal derivatives

(2011) Zahid H. Chohan et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Poly (DL-lactide-co-glycolide) (PLGA) Nanoparticles with Entrapped trans-Cinnamaldehyde and Eugenol for Antimicrobial Delivery Applications

(2011) Carmen Gomes et al.   JOURNAL OF FOOD SCIENCE

Development of a Peptide–Drug Conjugate for Prostate Cancer Therapy

(2011) Wanyi Tai et al.   MOLECULAR PHARMACEUTICS

Inhibition of Antibiotic-Resistant Staphylococcus aureus by the Broad-Spectrum Dihydrofolate Reductase Inhibitor RAB1

(2010) C. R. Bourne et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mutation Analysis of theMycobacterium leprae folP1Gene and Dapsone Resistance

(2010) Noboru Nakata et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The synthesis and biologic evaluation of anti-platelet and cytotoxic β-nitrostyrenes

(2010) Pei-Wen Hsieh et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Complementary and Alternative Interventions in Atopic Dermatitis

(2010) Joohee Lee et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Origins and Evolution of Antibiotic Resistance

(2010) J. Davies et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Treatment of War Wounds: A Historical Review

(2009) M. M. Manring et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Identification of antibacterial and antifungal pharmacophore sites for potent bacteria and fungi inhibition: Indolenyl sulfonamide derivatives

(2009) Zahid H. Chohan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antimicrobial studies on novel sulfonamides containing 4-azidomethyl coumarin

(2009) Mahantesha Basanagouda et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Anticonvulsant Sulfonamides/Sulfamates/Sulfamides with Carbonic Anhydrase Inhibitory Activity: Drug Design and Mechanism of Action

(2008) Bernard Masereel et al.   CURRENT PHARMACEUTICAL DESIGN

‘Metabolite-likeness’ as a criterion in the design and selection of pharmaceutical drug libraries

(2008) Paul D. Dobson et al.   DRUG DISCOVERY TODAY

History Revisited—Prontosil Red

(2008) Harish V. Iyer   JOURNAL OF EMERGENCY MEDICINE