Abundance of P‐Glycoprotein and Other Drug Transporters at the Human Blood‐Brain Barrier in Alzheimer’s Disease: A Quantitative Targeted Proteomic Study

Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors

(2019) Stephen S. Dominy et al.   Science Advances

Proteomic Quantification of Human Blood–Brain Barrier SLC and ABC Transporters in Healthy Individuals and Dementia Patients

(2019) Zubida M. Al-Majdoub et al.   MOLECULAR PHARMACEUTICS

Interindividual and Regional Variability in Drug Transporter Abundance at the Human Blood–Brain Barrier Measured by Quantitative Targeted Proteomics

(2019) Sarah Billington et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

NLRP3 inflammasome activation drives tau pathology

(2019) Christina Ising et al.   NATURE

P‐glycoprotein: a role in the export of amyloid‐β in Alzheimer's disease?

(2019) Amanda B. Chai et al.   FEBS Journal

The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM

(2018) Steffen E. Storck et al.   BRAIN BEHAVIOR AND IMMUNITY

Adenosine Augmentation Evoked by an ENT1 Inhibitor Improves Memory Impairment and Neuronal Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease

(2018) Chia-Chia Lee et al.   MOLECULAR NEUROBIOLOGY

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

Glucose Transporters in Brain: In Health and in Alzheimer’s Disease

(2016) Leszek Szablewski   JOURNAL OF ALZHEIMERS DISEASE

A 40 Reduces P-Glycoprotein at the Blood-Brain Barrier through the Ubiquitin-Proteasome Pathway

(2016) A. M. S. Hartz et al.   JOURNAL OF NEUROSCIENCE

The case for rejecting the amyloid cascade hypothesis

(2015) Karl Herrup   NATURE NEUROSCIENCE

P-glycoprotein expression and amyloid accumulation in human aging and Alzheimer's disease: preliminary observations

(2015) Catherine Chiu et al.   NEUROBIOLOGY OF AGING

Alzheimer's disease

(2015) Colin L. Masters et al.   Nature Reviews Disease Primers

Optimized Approaches for Quantification of Drug Transporters in Tissues and Cells by MRM Proteomics

(2014) Bhagwat Prasad et al.   AAPS Journal

Activity of P-Glycoprotein, a  -Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease

(2014) A. K. Deo et al.   JOURNAL OF NUCLEAR MEDICINE

ATP-binding cassette transporters P-glycoprotein and breast cancer related protein are reduced in capillary cerebral amyloid angiopathy

(2013) Anna Carrano et al.   NEUROBIOLOGY OF AGING

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice

(2011) Markus Krohn et al.   JOURNAL OF CLINICAL INVESTIGATION

Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors

(2011) Yasuo Uchida et al.   JOURNAL OF NEUROCHEMISTRY

Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels

(2011) Ramzi Shawahna et al.   MOLECULAR PHARMACEUTICS

ABC efflux transporters in brain vasculature of Alzheimer's subjects

(2010) Hasini C. Wijesuriya et al.   BRAIN RESEARCH

PET Imaging of MRP1 Function in the Living Brain: Method Development and Future Perspectives

(2010) T. Okamura et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Nonproteolytic Functions of Ubiquitin in Cell Signaling

(2009) Zhijian J. Chen et al.   MOLECULAR CELL

Consortium to Establish a Registry for Alzheimer’s Disease (CERAD): The first twenty years

(2008) Gerda G. Fillenbaum et al.   Alzheimers & Dementia

Blood–brain barrier P-glycoprotein function decreases in specific brain regions with aging: A possible role in progressive neurodegeneration

(2008) Anna L. Bartels et al.   NEUROBIOLOGY OF AGING

LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-β peptide in a blood–brain barrier in vitro model

(2008) Babak Nazer et al.   NEUROBIOLOGY OF DISEASE