Review
Pharmacology & Pharmacy
Yen-Tzu Chang, Tse-Hung Huang, Ahmed Alalaiwe, Erica Hwang, Jia-You Fang
Summary: The potential of using RNA interference (RNAi) for treating skin disorders is discussed in this review article. The design of siRNA delivery systems and the mechanisms of nanoparticle-mediated siRNA skin penetration are emphasized. Further clinical studies are needed to validate the findings from cellular and animal experiments, and the scalability and reproducibility of nanoparticle products should also be addressed.
EXPERT OPINION ON DRUG DELIVERY
(2023)
Review
Chemistry, Multidisciplinary
Jinho Yoon, Minkyu Shin, Ji-Young Lee, Sang-Nam Lee, Jin-Ha Choi, Jeong-Woo Choi
Summary: RNA interference (RNAi)-based therapeutics have not been used for cancer treatment due to their instability and microRNA (miRNA) delivery challenges. Plasmonic nanoparticle-based RNAi nanotherapeutics have been developed with specific properties for accurate cancer diagnosis and strong therapeutic effects. This review presents recent strategies and advances in plasmonic nanoparticle-based miRNA delivery for cancer detection and treatment, and discusses the challenges and potential opportunities in the field of RNAi-based theragnosis.
JOURNAL OF CONTROLLED RELEASE
(2022)
Review
Medicine, Research & Experimental
Santoshi Naik, Ajjappla Basavaraj Shreya, Ruchira Raychaudhuri, Abhijeet Pandey, Shaila A. Lewis, Manali Hazarika, Sulatha Bhandary, Bola Sadashiva Satish Rao, Srinivas Mutalik
Summary: This article discusses the current research on using siRNA-based gene silencing strategies to treat glaucoma, including discussions on ocular structures, administration routes, viral and non-viral vectors, as well as basic strategies and challenges in siRNA therapy. Different therapeutic targets for glaucoma, current siRNA-based drugs used in treatment, and strategies for siRNA-based treatment after glaucoma surgery are also briefly mentioned.
Article
Biochemistry & Molecular Biology
Sandrine Pelofy, Hugo Bousquet, Laure Gibot, Marie-Pierre Rols, Muriel Golzio
Summary: The ability to modulate deregulated genes by RNAi shows promise for treating certain diseases, including cancers. While in vitro studies have shown the direct transfer of negatively charged siRNA across the plasma membrane, understanding the efficiency of siRNA electrotransfer into 3D tissues remains a challenge. Nonetheless, the asymmetrical distribution of siRNA within multicellular spheroids is a key finding and suggests that spheroids could be a valuable alternative to animal experimentation.
BIOELECTROCHEMISTRY
(2021)
Review
Pharmacology & Pharmacy
Priyanga Ranasinghe, Melisande L. Addison, James W. Dear, David J. Webb
Summary: Post-transcriptional gene silencing can be achieved through siRNA therapy, which uses synthetic short double-stranded RNA molecules to specifically target and degrade mRNA transcripts. This technology offers advantages such as broad targeting capabilities and long-lasting effects. However, challenges in terms of pharmacokinetics and pharmacodynamics have been addressed through chemical modification and delivery systems. Several siRNA therapies have been approved for clinical use, but further advancements are needed to target organs beyond the liver and reach special sites.
BRITISH JOURNAL OF PHARMACOLOGY
(2023)
Article
Genetics & Heredity
Min-Sun Song, Jessica Alluin, John J. Rossi
Summary: Dicer-substrate small interfering RNAs (DsiRNAs) are artificial molecules with increased effectiveness compared to traditional 21-mer siRNAs, due to their novel asymmetric design. Four-looped DsiRNAs demonstrated higher gene silencing efficacy in cell experiments, highlighting the importance of Dicer in RNA interference pathways.
Article
Multidisciplinary Sciences
Manabu Yoshikawa, Yong-Woon Han, Hirofumi Fujii, Shu Aizawa, Tatsuya Nishino, Masayuki Ishikawa
Summary: In plants, siRNAs are amplified through cleavage by RISCs and play a crucial role in target repression. RDR6, SGS3, and SDE5 work together to ensure the specificity and efficiency of siRNA amplification and target inhibition in plants.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biochemistry & Molecular Biology
Anna S. Pavlova, Kristina I. Yakovleva, Anna V. Epanchitseva, Maxim S. Kupryushkin, Inna A. Pyshnaya, Dmitrii V. Pyshnyi, Elena I. Ryabchikova, Ilya S. Dovydenko
Summary: The study showed that siRNA modified with the phosphoryl guanidine (PG) group exhibited increased resistance to RNase A but decreased thermodynamic stability. However, PG-modified siRNA retained its activity when the modifications were introduced into the passenger strand.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Julien Ouvrard, Lisa Muniz, Estelle Nicolas, Didier Trouche
Summary: siRNAs can induce transcriptional silencing of chromatin-associated noncoding RNA through base-pairing with the target sequence. Transcriptional silencing occurs only in cis, and both Ago1 and Ago2 are involved.
MOLECULAR AND CELLULAR BIOLOGY
(2022)
Article
Medicine, General & Internal
Adam A. Walters, Baljevan Dhadwar, Khuloud T. Al-Jamal
Summary: Immune checkpoint targeting immunotherapy aims to manipulate interactions to engage the immune system in cancer treatment. Clinical use of monoclonal antibodies to block immunosuppressive interactions has been effective. Next generation strategies involve altering expression levels of immune checkpoint molecules with nucleic acids, including formulation within nanoparticulate systems.
Article
Immunology
Jianxiong Zeng, Zhifei Luo, Shupeng Dong, Xiaochun Xie, Xinyan Liang, Youzhen Yan, Qiming Liang, Zhen Zhao
Summary: The study identified a complex interaction network between ZIKV-derived viRNAs and their viral RNA targets, demonstrating that viRNA production from ZIKV mRNA depends on Dicer function and is a limiting factor for ZIKV virulence in NSCs.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Oncology
Ji Young Yoo, Margaret Yeh, Balveen Kaur, Tae Jin Lee
Summary: Aberrant gene and miRNA expression can drive cancer development, and the modulation of these expressions provides a therapeutic opportunity. Recent advances in RNA nanotechnology offer potential for miRNA therapy, but the lack of a delivery platform remains a challenge.
Article
Pharmacology & Pharmacy
Masaharu Somiya, Kanako Sakaeda, Yuta Ishii, Shun'ichi Kuroda
Summary: siRNA can specifically suppress gene expression through RNA interference (RNAi), but the efficiency of delivery is low. Researchers have successfully demonstrated highly efficient cytoplasmic delivery of siRNA and observed RNAi phenomena by combining non-cationic liposomes and the photosensitizer AlPcS2a.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Li Chen, Si Xiao, Li Jinbo, Zhang Yan
Summary: In the past decade, nucleic acid therapeutics, specifically RNA interference (RNAi) based technology, have rapidly developed and been widely used in treating various diseases. Small interfering RNA (siRNA) is a specific gene silencing method that has provided an effective means for studying gene function and developing new therapeutic strategies. Hence, there has been great interest in using siRNA as a therapy to target specific gene functions. However, to make RNAi technology valuable and effective, it is crucial to chemically modify siRNA and develop efficient siRNA delivery strategies. This review provides an overview of the chemical modifications of siRNA to enhance its stability and resistance to nucleases. It also discusses the development of siRNA delivery systems, including lipid-based and polymer-based carrier systems, to improve the pharmacokinetics and intracellular delivery of siRNA.
ACTA CHIMICA SINICA
(2023)
Review
Oncology
Junlin Xie, Shubin Wang
Summary: siRNA therapy has the potential to be one of the most effective methods for treating colorectal cancer liver metastasis (CRLM) by targeting major metastasis-related signaling pathways. However, the therapy faces challenges such as poor serum stability and nonspecific uptake, which require the development of delivery systems.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
(2022)
Article
Dermatology
Frances Fengzhi Lin, Yu Liu, Zijing Wu, Jing Li, Yanming Ding, Chunyan Li, Zhixia Jiang, Jing Yang, Kefang Wang, Jie Gao, Xiaohan Li, Xinhua Xia, Hongmei Liu, Xinxia Li, Xiaoyan Chen, Lei Yang, Xiuhua Fang, Ronghua Zhao, Jingfang Chen, Sonia Labeau, Stijn Blot
Summary: This study investigated pressure injury prevalence, risk factors, and prevention practices in adult intensive care patients in China. It found that overall and ICU-acquired prevalence rates were 12.26% and 4.31%, respectively, with repositioning being the most commonly used prevention strategy. The results provide a baseline reference for future preventive strategies in China.
INTERNATIONAL WOUND JOURNAL
(2022)
Article
Optics
G. Fan, K. Legare, V Cardin, X. Xie, R. Safaei, E. Kaksis, G. Andriukaitis, A. Pugzlys, B. E. Schmidt, J. P. Wolf, M. Hehn, G. Malinowski, B. Vodungbo, E. Jal, J. Luning, N. Jaouen, G. Giovannetti, F. Calegari, Z. Tao, A. Baltuska, F. Legare, T. Balciunas
Summary: This study demonstrates spatiotemporally resolved resonant magnetic scattering of inner-shell 4d electrons in a rare-earth composite ferrimagnetic system using a bright soft x-ray high harmonic generation source, which is relevant for future energy-efficient, high-speed spintronic applications. The results verify the underlying physics of the x-ray generation strategy and indicate potential for next-generation high-performance soft x-ray HHG-based sources in future applications requiring extremely high photon flux.
Review
Oncology
Lili Zhou, Manshu Zou, Yilin Xu, Peng Lin, Chang Lei, Xinhua Xia
Summary: Tumor immunotherapy is a powerful strategy for treating cancer by stimulating the immune system. However, the heterogeneity of tumors and immunosuppressive microenvironment make it difficult for immunotherapy to be effective. With the advancements in materials science and nanotechnology, innovative biomaterials and drug delivery systems can enhance the effectiveness of immunotherapy.
FRONTIERS IN ONCOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Yilin Xu, Min Wang, Shuangcheng Ning, Zhonglan Yang, Lili Zhou, Xinhua Xia
Summary: This study aimed to design solid lipid nanoparticles (SLNs) modified with glycyrrhetinic acid (GA) and/or folate (FA) to encapsulate cantharidin (CTD) for targeting hepatocellular carcinoma (HCC). The results showed that GA-FA-CSLNs and FA-CSLNs had stronger inhibitory effects on HCC cells, lower cytotoxicity and hemolysis, and increased inhibition of cell migration and apoptosis. The cell cycle analysis indicated cell arrest mainly in the S phase and G2/M phase. Competition suppression assays confirmed targeted effects on HCC cells. In vivo tumor suppression assays demonstrated excellent tumor inhibition rates for GA-FA-CSLNs and FA-CSLNs. These SLNs have promising potential for therapeutic intervention in HCC.
Review
Chemistry, Multidisciplinary
Mei Lu, Haonan Xing, Aiping Zheng, Yuanyu Huang, Xing-Jie Liang
Summary: The COVID-19 pandemic and mRNA vaccine development have brought nucleic acid therapeutics to the forefront. Nucleic acid drugs have shown promise in treating diseases at the genetic level, offering new treatment options and vaccine development against emerging health threats. However, challenges such as unfavorable physicochemical characteristics and off-target toxicity need to be addressed to advance nucleic acid therapeutics from the laboratory to clinical use.
ACCOUNTS OF CHEMICAL RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Manshu Zou, Yilin Xu, Peng Lin, Lili Zhou, Xinhua Xia
Summary: In this study, novel nano liposome delivery systems were constructed using cantharidin, a bioactive terpenoid in traditional Chinese medicine, for hepatocellular carcinoma therapy. The modified liposomes showed stronger cytotoxicity and increased inhibition of tumor cell migration compared to unmodified liposomes. In vivo experiments demonstrated improved distribution in the liver and excellent tumor inhibition. These findings provide a promising solution for improving drug targeting and highlight the potential of using poor solubility and high toxicity drugs for tumor therapy.
JOURNAL OF LIPOSOME RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Wenshu Cong, Li Meng, Yuanjie Pan, Han Wang, Jiahui Zhu, Yuanyu Huang, Qingli Huang
Summary: Population aging is a global issue, and this study presents a novel approach using Pd-based single-atom nanozymes to improve mitochondrial function and attenuate aging. The nanozyme mimics enzyme activities in the mitochondrial respiratory chain and enhances mitochondrial activities and abundance. Additionally, it demonstrates excellent anti-aging and neuroprotective effects through the activation of the mitochondrial unfolded protein response (UPRmt) pathway.
Article
Chemistry, Physical
Vaclav Hanus, Sarayoo Kangaparambil, Martin Richter, Lukas Hassfurth, Martin Dorner-Kirchner, Gerhard G. Paulus, Xinhua Xie, Andrius Baltuska, Stefanie Graefe, Markus Zeiler
Summary: We present a study on photoelectron circular dichroism (PECD) induced by intense few-cycle laser pulses, using methyloxirane as a model molecule. Our experiments demonstrate a strong dependence of double-ionization PECD on the carrier-envelope phase (CEP) of the laser pulses. Comparing with simulations, we attribute the observed CEP-dependence of PECD to the CEP-induced modulation of ionization from different areas of the wave functions of three dominant orbitals.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Chemistry, Multidisciplinary
Mei Liu, Qinmian Zhao, Jiayan Liu, Aijing Huang, XinHua Xia
Summary: This study investigated the scientific pharmacological activity of Buyang Huanwu decoction (BYHWD), a widely used traditional Chinese medicine, against type 2 diabetes mellitus (T2DM). The results showed that BYHWD effectively inhibited body fat accumulation and increased blood triglyceride levels, and improved gut microbiota dysbiosis and altered lipid metabolites induced by a high-fat diet in diabetic rats. These findings provide new insights into the mechanisms underlying the anti-T2DM effects of BYHWD and suggest the use of advanced systems biology methods in traditional Chinese medicine research.
FRONTIERS IN CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Xiaomin Zhang, Ge Yang, Wenjing Liu, Qing Liu, Zhuoran Wang, Kelong Fan, Feng Qu, Yuanyu Huang
Summary: Using CE-SELEX, four candidate aptamers with a stem-loop structure were selected targeting LRP6 protein. Among them, AptLRP6-A3 showed the highest affinity with LRP6-overexpressed human breast cancer cells. This LRP6 aptamer holds promise for rapid diagnosis and treatment of LRP6-related diseases.
Article
Biochemistry & Molecular Biology
Xiaomin Zhang, Ge Yang, Yi Zhao, Xuyan Dai, Wenjing Liu, Feng Qu, Yuanyu Huang
Summary: As a transmembrane serine protease, fibroblast activation protein (FAP) is expressed on the surface of fibroblasts associated with various epithelial-derived malignancies. It plays a role in tumorigenesis, progression, and immunosuppression. This study selected five candidate aptamers for FAP using capillary electrophoresis-systematic evolution of ligands by exponential enrichment (CE-SELEX), and determined their secondary structures and affinity to FAP protein through CE-laser-induced fluorescence (LIF) method. The FAP aptamers, especially AptFAP-A4, showed potential for rapid tumor diagnosis and targeted therapy.
Editorial Material
Medicine, Research & Experimental
Bo Hu, Yuanyu Huang
MOLECULAR THERAPY-NUCLEIC ACIDS
(2023)
Article
Pharmacology & Pharmacy
Mei Lu, Haonan Xing, Wanxuan Shao, Pengfei Wu, Yuchuan Fan, Huining He, Stefan Barth, Aiping Zheng, Xing-Jie Liang, Yuanyu Huang
Summary: Immunotherapy has transformed cancer treatment, but it only works well in a small subset of patients. Combining immunotherapy with synergistic anti-tumor drugs has the potential to boost treatment outcomes, but research in this area is limited. This study establishes a novel combined cancer treatment approach by combining PAK4 silencing with immunogenic phototherapy in engineered extracellular vesicles. The engineered vesicles demonstrate potent PAK4 silencing and robust immunogenic phototherapy, resulting in effective anti-tumor effects in vitro and in vivo.
ACTA PHARMACEUTICA SINICA B
(2023)
Article
Optics
Xinhua Xie, Adrian l. Cavalieri, Steven l. Johnson
Summary: In this study, we demonstrate the self-compression of near-infrared laser pulses down to 8.8 fs in ambient air using self-phase modulation in air and negative dispersion in laser-induced plasma. The compressed pulses are achieved through conical radiation, eliminating the need for additional dispersion compensation. This offers a simple and compact approach to generate sub-10 fs laser pulses for time-resolved applications in ultrafast diagnostics and spectroscopy.
Review
Materials Science, Biomaterials
Wenjing Liu, Yuanyu Huang
Summary: Cell membrane-coating nanotechnology involves using cell membranes derived from different cell types to coat synthetic nanoparticles, enabling precise disease treatment. Cell membranes from different sources have different functions, making them suitable for creating novel nanotherapeutics and advancing nanomedicine for improved cancer treatment.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Chemistry, Multidisciplinary
Qian Wu, Yubo Cui, Guifeng Xia, Jinlong Yang, Shuming Du, Xinhong Xiong, Li Yang, Dong Xu, Xu Deng, Jiaxi Cui
Summary: Passive daytime radiative cooling (PDRC) technology, while promising for global spacing cooling, faces limitations in practical application due to reduced cooling effectiveness caused by wear and dirt contamination. Researchers have developed a renewable armor structure using fluorinated hollow glass microspheres to enhance the anti-fouling and cooling properties of PDRC coatings. The coatings exhibit high solar reflectance and thermal emittance, leading to significant temperature reduction below ambient temperature.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Qiang Bei, Bei Zhang, Kaifeng Wang, Shiming Zhang, Guichuan Xing, Clement Cabanetos
Summary: The power conversion efficiency (PCE) of organic solar cells (OSCs) has reached 20% in recent years, thanks to the advantages of organic photoactive materials. Benzothiadiazole (BT) has attracted significant research attention as a building block of OSCs. OSCs based on BT structure have shown diversity, and the increasing PCE values indicate a promising future for OSCs. This review analyzes the progress made in the last decades, focusing on effective BT small-molecules and BT polymers for OSCs. The structure-property relationships, donor-acceptor matching criteria, and morphology control approaches are discussed. The remaining challenges and a personal perspective on the future advancement of OSCs are summarized.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Rong He, Dandan Tang, Ningge Xu, Heng Liu, Kun Dou, Xuejun Zhou, Fabiao Yu
Summary: Nasopharyngeal carcinoma (NPC) is a common malignant tumor of the head and neck, with a high incidence in China and Southeast Asian countries. In this study, a novel near-infrared fluorescent probe, SNAFL-GSH, was designed and synthesized for the detection of glutathione (GSH). The probe showed selective detection of GSH and the ability to distinguish normal and cancer cells. It has great potential for application in the diagnosis and evaluation of NPC.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhukang Guo, Baijiang Jin, Yile Fang, Lian Jin, Song Li, Yan Deng, Zhu Chen, Hui Chen, Yuanying Zhang, Rabia Usman, Nongyue He
Summary: This study isolated primary cells that can be stably passaged from spontaneous tumors of genetically engineered pancreatic ductal adenocarcinoma model mice and used an autonomously developed automated screening instrument for efficient nucleic acid aptamer screening. The obtained aptamers were affinity verified at the cellular level. The study also investigated the impact of cell growth environment difference on the recognition ability of aptamers and confirmed the targeting ability and drug loading ability of the aptamer.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhongshan Yang, Qiqi Zhang, Hui Song, Xin Chen, Jiwei Cui, Yanhui Sun, Lequan Liu, Jinhua Ye
Summary: Methane chemistry is a significant area of research in catalysis. Converting methane into value-added chemicals is desirable but challenging due to its high C-H bonding energy and lack of pi bonding or unpaired electrons. Photocatalytic partial oxidation of methane to liquid oxygenates is a promising technology for achieving high efficiency and selectivity under mild conditions. The choice and activation of oxidants are crucial for its performance.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Peng Shan, Jing Liao, Jiayi Li, Chengyan Wang, Jie Zhou, Linqiang Mei, Yunlu Dai, Qiang Wang, Wenyan Yin
Summary: This study reports an oral radioprotectant Gel@GYY that combines a gelatin-based hydrogel and a pH-responsive hydrogen sulfide donor. Gel@GYY has excellent adhesion and sustained release properties, allowing it to release H2S in the gastrointestinal tract and effectively scavenge free radicals induced by radiation. It also reduces inflammation and has biodegradable properties.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lu Liu, Ziyi Liu, Jingnan Cui, Guiling Ning, Weitao Gong
Summary: The development of new metal-free heterogeneous catalysts has been the subject of extensive research. In this study, a new Troger's base (TB)-derived porous organic polymer (POPs) was designed and prepared by integrating multifunctional monomers. The resulting polymer, which combines the advantages of pillar[5]arene macrocycle and TB moiety, exhibited enhanced catalytic performance in Knoevenagel condensation and CO2 conversion, serving as an effective metal-free catalyst. This work provides a new strategy for fabricating metal-free heterogeneous catalysts based on macrocyclic POPs.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leyong Zhou, Changyin Yang, Weitao Dou, Tongxia Jin, Haibo Yang, Lin Xu
Summary: This review summarizes the application of micro/nanofluidic techniques in constructing supramolecular assemblies of different scales, and highlights the advantages of these techniques over conventional synthesis methods. Furthermore, it emphasizes the potential of micro/nanofluidic systems in improving our understanding of supramolecular self-assembly processes.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Yanchao Jin, Suixiaochen Chen, Peiwen Huang, Xiongjian Chen, Chun-Yan Lin, Li-Ping Li, Xiao Chen, Rui Ding, Jianxi Liu, Riyao Chen
Summary: In this study, magnesium and coconut shell carbon were used to disinfect water by adsorbing copper(II) and converting dissolved oxygen to hydrogen peroxide through Mg corrosion. The copper was enriched on the carbon surface and efficiently catalyzed the hydrogen peroxide to inactivate E.coli. The process showed promising disinfection performance both in laboratory experiments and real wastewater treatment.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Haihong Lai, Zehong Chen, Hao Zhuo, Yijie Hu, Xuan Zhao, Jiwang Yi, Hongzhi Zheng, Ge Shi, Yifan Tong, Ling Meng, Xinwen Peng, Linxin Zhong
Summary: By altering the pyrolysis route of cellulose nanofiber, the structural defects of carbon aerogels can be reduced, leading to improved compressibility and stress retention, as well as higher stress sensor sensitivity and temperature coefficient.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lina Guo, Jinsong Ding, Wenhu Zhou
Summary: Bacteria-based tumor therapy has resurfaced due to the revolution of tumor immunotherapy, offering unique solutions for traditional tumor treatments. Bacteria with active tropism can selectively colonize tumor sites and suppress tumor growth through various mechanisms, making them attractive tools for tumor treatment. This critical review introduces recent advances in bacteria-based tumor therapy, including bacterial properties, their benefits for tumor therapy, anti-tumor mechanisms, challenges, and future perspectives.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lan Liang, Chuanbin Wang, Xukai Lu, Yunan Sun, Beibei Yan, Ning Li, Guanyi Chen, Li'an Hou
Summary: This study investigates the interactions between phenol and benzaldehyde in the ECH process through experiments and theoretical calculations. The results show that phenol can accelerate the conversion of benzaldehyde, while benzaldehyde inhibits the conversion of phenol. The research provides a theoretical basis for the application of ECH in practical bio-oil upgrading.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Pengcheng Fan, Yuhao He, Junan Pan, Ning Sun, Qiyu Zhang, Chen Gu, Kang Chen, Weinan Yin, Longlu Wang
Summary: This study focuses on the recent progress in hydrogen evolution reaction (HER) based on photothermal effect. It introduces the main pathways of photothermal conversions applied in H2 evolution, summarizes the functions of the photothermal effect, and presents a method to improve the catalytic system through thermal means. The study also discusses the challenges and outlook in this promising area.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leiduo Lai, Hongyu Zhou, Yichen Hong, Mengfan Luo, Yang Shi, Heng Zhang, Zhaokun Xiong, Gang Yao, Bo Lai
Summary: In this study, a facile ammonia reduction strategy was proposed and a novel FeVO3-x catalyst was synthesized for the activation of peroxymonosulfate (PMS) to degrade the pharmaceutical carbamazepine (CBZ). The results showed that the system could rapidly degrade CBZ and generate various active species involved in the degradation process.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Tangxin Xiao, Xiuxiu Li, Liangliang Zhang, Kai Diao, Zheng-Yi Li, Xiao-Qiang Sun, Leyong Wang
Summary: This study presents the construction of a supramolecular light harvesting system based on sequential energy transfer. The system demonstrates tunable fluorescence emission through self-assembly of polymers into nanoparticles, achieving efficient two-step light harvesting.
CHINESE CHEMICAL LETTERS
(2024)