Small Interfering RNAs Targeting a Chromatin-Associated RNA Induce Its Transcriptional Silencing in Human Cells

Dicer dependent tRNA derived small RNAs promote nascent RNA silencing

(2022) Arianna Di Fazio et al.   NUCLEIC ACIDS RESEARCH

RNAi Based Therapeutics and Novel RNA Bioengineering Technologies

(2022) Gavin M. Traber et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Very long intergenic non-coding (vlinc) RNAs directly regulate multiple genes in cis and trans

(2021) Huifen Cao et al.   BMC BIOLOGY

RNAi-directed knockdown induces nascent transcript degradation and premature transcription termination in the nucleus

(2021) Jin You et al.   Cell Discovery

Circular ANRIL isoforms switch from repressors to activators of p15/CDKN2B expression during RAF1 oncogene-induced senescence

(2020) Lisa Muniz et al.   RNA Biology

Long non-coding RNAs: from disease code to drug role

(2020) Yuanyuan Chen et al.   Acta Pharmaceutica Sinica B

Mechanism of cancer: Oncohistones in action

(2018) Lei Qiu et al.   Journal of Genetics and Genomics

Argonaute-miRNA Complexes Silence Target mRNAs in the Nucleus of Mammalian Stem Cells

(2018) Aishe A. Sarshad et al.   MOLECULAR CELL

Control of Gene Expression in Senescence through Transcriptional Read-Through of Convergent Protein-Coding Genes

(2017) Lisa Muniz et al.   Cell Reports

Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells

(2016) Roya Kalantari et al.   RNA

Transcriptional silencing of long noncoding RNA GNG12-AS1 uncouples its transcriptional and product-related functions

(2016) Lovorka Stojic et al.   Nature Communications

Cell Type- and Tissue Context-dependent Nuclear Distribution of Human Ago2

(2015) Nishi R. Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Widespread Inducible Transcription Downstream of Human Genes

(2015) Anna Vilborg et al.   MOLECULAR CELL

A vlincRNA participates in senescence maintenance by relieving H2AZ-mediated repression at the INK4 locus

(2015) Sandra Lazorthes et al.   Nature Communications

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA

(2014) Eleanor White et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNAi Factors Are Present and Active in Human Cell Nuclei

(2014) Keith T. Gagnon et al.   Cell Reports

RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond

(2013) Stephane E. Castel et al.   NATURE REVIEWS GENETICS

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer

(2013) Georges St Laurent et al.   GENOME BIOLOGY

Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells

(2012) Moussa Benhamed et al.   NATURE CELL BIOLOGY

Transcriptional regulation by miRNA mimics that target sequences downstream of gene termini

(2011) Scott T. Younger et al.   Molecular BioSystems

Parallel pathways in RAF-induced senescence and conditions for its reversion

(2011) M Jeanblanc et al.   ONCOGENE

Transcriptional gene silencing of HIV-1 through promoter targeted RNA is highly specific

(2011) Kazuo Suzuki et al.   RNA Biology

Transcriptional regulation by small RNAs at sequences downstream from 3′ gene termini

(2010) Xuan Yue et al.   Nature Chemical Biology

Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter

(2010) Yongjun Chu et al.   NUCLEIC ACIDS RESEARCH

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells

(2009) Sara Napoli et al.   EMBO JOURNAL

Maintenance of a constitutive heterochromatin domain in vertebrates by a Dicer-dependent mechanism

(2009) Keith E. Giles et al.   NATURE CELL BIOLOGY

Control of alternative splicing through siRNA-mediated transcriptional gene silencing

(2009) Mariano Alló et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells

(2009) Peter G. Hawkins et al.   NUCLEIC ACIDS RESEARCH

Intended transcriptional silencing with siRNA results in gene repression through sequence-specific off-targeting

(2009) J. Moses et al.   RNA

Effect of 27nt Small RNA on Endothelial Nitric-Oxide Synthase Expression

(2008) Ming-Xiang Zhang et al.   MOLECULAR BIOLOGY OF THE CELL

Antisense transcripts are targets for activating small RNAs

(2008) Jacob C Schwartz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY