Review
Polymer Science
Izzat Zulkiflee, Syafira Masri, Mazlan Zawani, Atiqah Salleh, Ibrahim Nor Amirrah, Mohd Farhanulhakim Mohd Razip Wee, Salma Mohamad Yusop, Mh Busra Fauzi
Summary: Silicon-based biomaterials have gained significant breakthroughs in various industries, including clinical and biomedical applications. Their highly favorable properties, such as excellent biocompatibility, high surface area, mechanical strength, and selectivity, make them attractive for applications like film, hydrogel, nanoparticles, etc. Exciting results have also been observed in cell culture, cell growth, and tissue engineering. This article provides a simple review of the unique properties of silicon and discusses its future application perspectives in the biomedical field, with the goal of generating broader interest in silicone-based materials for wound healing research.
Review
Nanoscience & Nanotechnology
Mingran Zhang, Jiaxue Liu, Tongtong Zhu, Hanxiang Le, Xukai Wang, Jinshan Guo, Guangyao Liu, Jianxun Ding
Summary: Bone adhesives are expected to have significant advantages in treating bone injuries compared to traditional internal fixation devices. Different research directions of bone adhesives, such as liquid scaffold and liquid plate, are summarized. Recent advances in mechanical strength, osseointegration, osteoconductivity, and osteoinductivity of bone adhesives are discussed.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Review
Engineering, Biomedical
Guanyin Zhu, Tianxu Zhang, Miao Chen, Ke Yao, Xinqi Huang, Bo Zhang, Yazhen Li, Jun Liu, Yunbing Wang, Zhihe Zhao
Summary: Bone-tissue defects are a global issue, with autologous and allogeneic bone grafting failing to achieve ideal therapeutic effects. This has led researchers to explore novel bone-regeneration methods, with the development of BTE scaffolds at the forefront. By delving into bone physiology and healing mechanisms, biomimicking and bioinspired BTE scaffolds are making progress.
BIOACTIVE MATERIALS
(2021)
Article
Nanoscience & Nanotechnology
Pengfei Cai, Chunchun Li, Yangfan Ding, Hanting Lu, Xiao Yu, Jie Cui, Fan Yu, Hongsheng Wang, Jinglei Wu, Mohamed EL-Newehy, Meera Moydeen Abdulhameed, Liang Song, Xiumei Mo, Binbin Sun
Summary: This research introduces a novel method that combines electrospun nanofibers with 3D printing techniques to fabricate composite scaffolds for bone defect treatment. Compared to nanoparticle-reinforced scaffolds, these scaffolds infused with nanofibers exhibit superior mechanical attributes and bioactivity.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Review
Biotechnology & Applied Microbiology
Zimu Mao, Baoshi Fan, Xinjie Wang, Ximeng Huang, Jian Guan, Zewen Sun, Bingbing Xu, Meng Yang, Zeyi Chen, Dong Jiang, Jiakuo Yu
Summary: The use of tissue engineering scaffold, especially biomaterials, has shown significant effectiveness in tendon-bone healing and can be enhanced by biological interventions. Current research is mainly focused on animal models, calling for further clinical trials to explore the full potential of these approaches in clinical practice.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Applied
Fatemeh Doustdar, Ali Olad, Marjan Ghorbani
Summary: Chitosan, cellulose nanocrystals, and halloysite nanotubes were used to fabricate a three-dimensional nanocomposite scaffold with improved properties. The addition of halloysite nanotubes enhanced the scaffold's thermal stability, mechanical characteristics, water uptake, and degradation rate, demonstrating its potential for bone tissue engineering applications. Additionally, the scaffold showed good biomineralization, cell proliferation, and cell attachment, and the capability for curcumin delivery was successfully demonstrated through cell proliferation and antibacterial studies.
CARBOHYDRATE POLYMERS
(2022)
Article
Biochemistry & Molecular Biology
Mehdi Azizi, Amin Shavandi, Masoud Hamidi, Shayan Gholizadeh, Mahnaz Mohammadpour, Mohammad Saeid Salami, Hadi Samadian
Summary: Tissue engineering is an innovative approach that combines engineering, biomaterials, and biomedicine to improve conventional bone defect treatment. This study developed bioengineered electroactive and bioactive mineralized carbon nanofibers as a scaffold for bone tissue engineering. The fabricated scaffold showed osteoactivity, electrical conductivity, and biocompatibility, making it an effective solution for bone tissue engineering.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Chemistry, Multidisciplinary
Weijuan Huang, Shi Cheng, Xiaolan Wang, Yu Zhang, Lingyun Chen, Lina Zhang
Summary: This research introduces a catechol-conjugated chitosan multi-functional hydrogel that can rapidly achieve adhesion and hemostasis during surgery, with self-healing capabilities. In vivo experiments using a rabbit ilium bone defect model demonstrate the rapid hemostatic effect of the hydrogel and its promotion of bone regeneration.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Engineering, Biomedical
Cam-Hoa Mac, Hao-Yu Chan, Yi-Hsuan Lin, Amit Kumar Sharma, Hsiang-Lin Song, Yi-Sheng Chan, Kun-Ju Lin, Yu-Jung Lin, Hsing-Wen Sung
Summary: This study proposes a biomaterial-based scaffold consisting of radially aligned mineralized collagen fibers and nanosilicon. The scaffold guides the directional infiltration and migration of reparative cells and releases hydrogen gas and silicic acid, promoting bone regeneration.
Article
Engineering, Biomedical
Zhuo Li, Haixing Wang, Kunyu Zhang, Boguang Yang, Xian Xie, Zhengmeng Yang, Lingchi Kong, Peng Shi, Yuan Zhang, Yi-Ping Ho, Zhi-Yong Zhang, Gang Li, Liming Bian
Summary: The research assembled a biomimetic hyaluronic acid nanocomposite hydrogel with bisphosphonates (BPs), and demonstrated its expedited release of BPs in an acidic environment. The in vitro studies showed that the hydrogel inhibits mature osteoclastic differentiation, while promoting the initial differentiation of primary macrophages to preosteoclasts. In vivo evaluation confirmed the hydrogel's ability to enhance in situ bone regeneration.
BIOACTIVE MATERIALS
(2022)
Article
Engineering, Biomedical
Minglei Yang, Jiafei Chen, Yi Chen, Weikang Lin, Hai Tang, Ziwen Fan, Long Wang, Yunlang She, Feng Jin, Lei Zhang, Weiyan Sun, Chang Chen
Summary: A scaffold-free modular strategy for tracheal engineering is developed, which constructs a complex tracheal substitute by laminating a cartilage sheet and a temperature-sensitive epithelium sheet. This substitute exhibits native-like structure and function, showing great clinical potential for tracheal reconstruction.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Engineering, Biomedical
N. Contessi Negrini, A. Angelova Volponi, C. A. Higgins, P. T. Sharpe, A. D. Celiz
Summary: Developmental TE is a novel paradigm aiming to obtain tissues and organs with correct biomorphology and biofunctionality by mimicking the morphogenetic processes leading to the tissue/organ generation in the embryo. Successful applications have been reported for ectodermal appendages such as teeth, hair follicles and glands, with a focus on accurate selection of cell sources, scaffolds, and cell culture configurations to replicate in vivo morphogenetic cues.
MATERIALS TODAY BIO
(2021)
Article
Engineering, Biomedical
Sangil Min, David Cleveland, In Kap Ko, Ji Hyun Kim, Hee Jo Yang, Anthony Atala, James J. Yoo
Summary: By incorporating vascular endothelial growth factor (VEGF) into the vascular scaffold, improved angiogenic capability was achieved, promoting vascularization, reducing apoptosis of implanted cells, and forming hybrid renal tubule-like structures.
ACTA BIOMATERIALIA
(2021)
Review
Engineering, Biomedical
Mahsa Janmohammadi, Zahra Nazemi, Amin Orash Mahmoud Salehi, Amir Seyfoori, Johnson John, Mohammad Sadegh Nourbakhsh, Mohsen Akbari
Summary: Cellulose-based scaffolds have great potential in bone tissue engineering due to their non-toxicity, biocompatibility, renewable nature, and low cost. They can deliver growth factors and antibiotics directly to the site of impaired bone tissue to promote tissue repair. This review focuses on the various types of cellulose-based composite scaffolds used for bone drug delivery systems and bone regeneration, highlighting their physicochemical, mechanical, and biological properties.
BIOACTIVE MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Farzaneh Jabbari, Valiollah Babaeipour, Samaneh Bakhtiari
Summary: Nerve injuries and neurodegenerative disorders pose serious medical challenges, but new electroactive biomaterials like bacterial cellulose (BC) show promise in promoting nerve regeneration when combined with conductive structures. Electrical stimulation has positive effects on cellular activity, including adhesion, proliferation, migration, and differentiation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Food Science & Technology
Khashayar Shahin, Hongduo Bao, Shujiao Zhu, Abbas Soleimani-Delfan, Tao He, Mojtaba Mansoorianfar, Ran Wang
Summary: This study identified and characterized three highly effective antibacterial phages with stable bacteriolytic activity under different conditions. These phages exhibited extensive lytic effects on a wide range of E. coli strains, including pathogenic and antibiotic-resistant ones. Food testing confirmed that the phage cocktail was able to completely inhibit the growth of E. coli in food matrices, making them ideal candidates for further development as bio-control agents for E. coli in food production.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Reza Rahighi, Mohammad Panahi, Omid Akhavan, Mojtaba Mansoorianfar
Summary: Multi-component nanocomposite thin films were prepared using cathodic electrophoretic deposition under different isostatic pressures. The samples prepared at high pressure condition showed higher drug loading/releasing and resulted in higher biocompatibility and bio-functionality of osteoblast cells on the thin films.
MATERIALS CHEMISTRY AND PHYSICS
(2021)
Article
Engineering, Environmental
Zahid Hussain, Ismat Ullah, Xingzhu Liu, Wenqi Shen, Pi Ding, Yajie Zhang, Tong Gao, Mojtaba Mansoorianfar, Tian Gao, Renjun Pei
Summary: Bone defects pose challenges to surgery and require cell-guided bioengineering methods for support and restoration of bone function. This study investigated the use of iron-reinforced hydroxyapatite nanorod, collagen/polycaprolactone, and tannic acid to create inorganic-organic nanofibers for coating an implant surface. The results demonstrated that the nanocomposite mimics the bone matrix, promoting cell attachment, proliferation, differentiation, and bone remodeling. It shows great potential for enhancing osteointegration.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Environmental Sciences
Mojtaba Mansoorianfar, Khashayar Shahin, Akbar Hojjati-Najafabadi, Renjun Pei
Summary: This study introduced Ti3C2 MXene nanofragments as a modified virus vector to be used in high-risk bacterial environments, showing enhanced antibacterial efficacy through the physical interaction with bacterial cell membranes and the specific targeting capacity of bacteriophages. The Ti3C2 MXene-functionalized bacteriophage demonstrated fast and efficient attachment to bacterial hosts, high antibacterial potential, and effectively reduced bacterial contamination in water samples by 99.99%.
Article
Immunology
Khashayar Shahin, Lili Zhang, Mohammad Hossein Mehraban, Jean-Marc Collard, Abolghasem Hedayatkhah, Mojtaba Mansoorianfar, Abbas Soleimani-Delfan, Ran Wang
Summary: This article provides a comprehensive review/perspective of the potential applications of bacteriophages in combating the COVID-19 pandemic and the post-COVID era. It discusses the use of bacteriophages for treatment, vaccine development, and virus detection techniques, highlighting their potential for ecological and epidemiological modeling.
MICROBIAL PATHOGENESIS
(2022)
Review
Environmental Sciences
Akbar Hojjati-Najafabadi, Mojtaba Mansoorianfar, Tongxiang Liang, Khashayar Shahin, Hassan Karimi-Maleh
Summary: This study reviews the idea of using magnetic sensors to control and monitor hazardous pollutants in water resources. It discusses water pollutants and toxicology in different water sources and emphasizes the potential of magnetic materials as sensors for pollutant control. The study highlights the importance of controlling hazardous pollutants and the environmental applications of magnetic nano sensors in water resources.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Engineering, Environmental
Akbar Hojjati-Najafabadi, Mojtaba Mansoorianfar, Tongxiang Liang, Khashayar Shahin, Yangping Wen, Abbas Bahrami, Ceren Karaman, Najmeh Zare, Hassan Karimi-Maleh, Yasser Vasseghian
Summary: The increase in pollutants released into water resources, such as hazardous refractory contaminations, organic dyes, pharmaceutical and pesticide contaminants, due to population growth and global industrialization, has become a major health issue worldwide. Magnetic MXene nanocomposites, which possess unique properties, easy production, low-cost preparation, and excellent pollutant degradation abilities, show great promise for various applications including biosensors, cancer theragnostic, imaging strategies, and particularly water treatment. This paper provides a review of the use of magnetic-MXene nanocomposites for removing contaminants from aqueous environments, discussing the concept of magnetic nanomaterials in water treatment, MXene applications and implications for water and wastewater pollutant degradation, and the role of magnetic-MXene nanocomposites in water treatment. Future trends in MXene and magnetic-MXene nanomaterials for water treatment and environmental applications are also discussed.
JOURNAL OF WATER PROCESS ENGINEERING
(2022)
Article
Microbiology
Khashayar Shahin, Abbas Soleimani-Delfan, Lili Zhang, Abolghasem Hedayatkhah, Mojtaba Mansoorianfar, Hongduo Bao, Mohadeseh Barazandeh, Jalil Enteshari, Ran Wang
Summary: We report the genome of phage SAP012, isolated against Salmonella enterica serovar Typhimurium, which is quite similar to previously sequenced Salmonella phage genomes at the nucleotide level and lacks antibiotic resistance or virulence genes.
MICROBIOLOGY RESOURCE ANNOUNCEMENTS
(2022)
Article
Chemistry, Multidisciplinary
Hafezeh Nabipour, Mojtaba Mansoorianfar, Yuan Hu
Summary: Metal-organic frameworks, specifically a copper-based HKUST-1 framework, were prepared through solvothermal method and loaded with baclofen as a model drug. The bio-nanocomposite of CMC/baclofen-HKUST-1 showed improved drug release controllability, homogeneity, and delivery under gastrointestinal conditions. This composite also exhibited considerable cytotoxicity against human colon cells.
Article
Environmental Sciences
Zahid Hussain, Salim Ullah, Jincong Yan, Zhili Wang, Ismat Ullah, Zia Ahmad, Ye Zhang, Yi Cao, Li Wang, Mojtaba Mansoorianfar, Renjun Pei
Summary: A tannin-reinforced nanofibrous membrane was fabricated via electrospinning, which showed superior thermal and mechanical properties. The membrane changed color in response to Fe3+ ions and exhibited a linear relationship with Fe3+ ion concentration. It also had a high adsorption capacity for methylene blue and could capture bacteria bound to Fe3+ ions.
Review
Chemistry, Analytical
Salim Ullah, Qurat ul Ain Zahra, Mojtaba Mansoorianfar, Zahid Hussain, Ismat Ullah, Wenjing Li, Edward Kamya, Shah Mehmood, Renjun Pei, Jine Wang
Summary: Heavy metal ions as metallic pollutants pose a global issue due to their harmful effects on the aquatic ecosystem and human health. Conventional detection methods have limitations, making the development of an efficient method for on-site and real-time detection of heavy metal residues crucial. Aptamer-based sensors, with their high sensitivity, ease of production, simplicity, specificity, stability, low immunogenicity, and cost-effectiveness, offer advantages over antibodies. When combined with nanomaterials, nucleic acid aptamers can selectively bind to metal ions, enabling on-site monitoring of their residues.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Article
Environmental Sciences
Mojtaba Mansoorianfar, Hafezeh Nabipour, Farshid Pahlevani, Yuewu Zhao, Zahid Hussain, Akbar Hojjati-Najafabadi, Hien Y. Hoang, Renjun Pei
Summary: This review presents the latest suggested adsorption mechanisms, kinetics, and isotherms of MOFs-based materials for removing cadmium ions, comparing different MOFs and their mechanisms of cadmium ion removal. The future role of MOFs in removing environmental contaminants is discussed, along with the research gap and limitations of MOFs as adsorbents in actual applications.
ENVIRONMENTAL RESEARCH
(2022)
Article
Materials Science, Multidisciplinary
Zahra Sadeghi, Mojtaba Mansoorianfar, Masoud Panjepour, Mahmood Meratian
Summary: In recent years, there has been a significant interest in metal foams due to their unique physical and mechanical properties as well as their applications. This study investigates the fabrication of magnesium foams using viscose rayon fibers as a hydrogen source and examines the chemical composition, pyrolysis, and structure of the foams. The results demonstrate that viscose rayon fibers can effectively serve as a foaming agent for producing magnesium foams with high porosity and potentially useful for load-bearing, weight-saving, and impact-absorbing structures.
JOURNAL OF MATERIALS SCIENCE
(2023)
