Human Hsp90 cochaperones: perspectives on tissue-specific expression and identification of cochaperones with similar in vivo functions

Hsp90 Co-chaperones Form Plastic Genetic Networks Adapted to Client Maturation

(2020) Maximilian M. Biebl et al.   Cell Reports

Tomm34 is commonly expressed in epithelial ovarian cancer and associates with tumour type and high FIGO stage

(2019) Petr Muller et al.   Journal of Ovarian Research

NudC regulates photoreceptor disk morphogenesis and rhodopsin localization

(2019) Evan R. Boitet et al.   FASEB JOURNAL

Myoglobin maturation is driven by the hsp90 chaperone machinery and by soluble guanylyl cyclase

(2019) Arnab Ghosh et al.   FASEB JOURNAL

The EMBL-EBI search and sequence analysis tools APIs in 2019

(2019) Fábio Madeira et al.   NUCLEIC ACIDS RESEARCH

Crystal structures of the naturally fused CS and cytochrome b 5 reductase (b 5R) domains of Ncb5or reveal an expanded CS fold, extensive CS–b 5R interactions and productive binding of the NAD(P)+ nicotinamide ring

(2019) David R. Benson et al.   Acta Crystallographica Section D-Structural Biology

Hsp90 and Its Co-Chaperones in Neurodegenerative Diseases

(2019) Anastasiia Bohush et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aha-type co-chaperones: the alpha or the omega of the Hsp90 ATPase cycle?

(2019) Paul LaPointe et al.   BIOLOGICAL CHEMISTRY

Role of the Novel Hsp90 Co-Chaperones in Dynein Arms’ Preassembly

(2019) Hanna Fabczak et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dynein 1 supports spermatid transport and spermiation during spermatogenesis in the rat testis

(2018) Qing Wen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

NudCL2 is an Hsp90 cochaperone to regulate sister chromatid cohesion by stabilizing cohesin subunits

(2018) Yuehong Yang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The mTOR Independent Function of Tsc1 and FNIPs

(2018) Rebecca A. Sager et al.   TRENDS IN BIOCHEMICAL SCIENCES

Identification of Potential Gene Interactions in Heart Failure Caused by Idiopathic Dilated Cardiomyopathy

(2018) Huijuan Huang et al.   MEDICAL SCIENCE MONITOR

The HSP90 chaperone machinery

(2017) Florian H. Schopf et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases

(2017) Rachel E. Lackie et al.   Frontiers in Neuroscience

Imbalances in the Hsp90 Chaperone Machinery: Implications for Tauopathies

(2017) Lindsey B. Shelton et al.   Frontiers in Neuroscience

Molecular Chaperone Accumulation in Cancer and Decrease in Alzheimer's Disease: The Potential Roles of HSF1

(2017) Stuart K. Calderwood et al.   Frontiers in Neuroscience

The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90

(2017) Katie L. I. M. Blundell et al.   PLoS One

Novel roles of FKBP5 in muscle alteration induced by gravity change in mice

(2016) Takeshi Shimoide et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CacyBP/SIP — Structure and variety of functions

(2016) Agnieszka M. Topolska-Woś et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Interaction of a Novel Chaperone PhLP2A With the Heat Shock Protein Hsp90

(2016) Łucja Krzemień-Ojak et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A Remodeled Hsp90 Molecular Chaperone Ensemble with the Novel Cochaperone Aarsd1 Is Required for Muscle Differentiation

(2016) Pablo C. Echeverría et al.   MOLECULAR AND CELLULAR BIOLOGY

Hsp90 and p23 Molecular Chaperones Control Chromatin Architecture by Maintaining the Functional Pool of the RSC Chromatin Remodeler

(2016) Frank J. Echtenkamp et al.   MOLECULAR CELL

Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer’s disease with OSBPL6, PTPRG and PDCL3

(2016) C Herold et al.   MOLECULAR PSYCHIATRY

Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase

(2016) K. A. Verba et al.   SCIENCE

Emerging roles of NudC family: from molecular regulation to clinical implications

(2016) Qiqin Fu et al.   Science China-Life Sciences

Heat Shock Proteins Promote Cancer: It's a Protection Racket

(2016) Stuart K. Calderwood et al.   TRENDS IN BIOCHEMICAL SCIENCES

The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding

(2016) Mark R. Woodford et al.   Nature Communications

Regulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90β

(2016) Yi-Jheng Peng et al.   Scientific Reports

Cytoplasmic Ubiquitin-Specific Protease 19 (USP19) Modulates Aggregation of Polyglutamine-Expanded Ataxin-3 and Huntingtin through the HSP90 Chaperone

(2016) Wen-Tian He et al.   PLoS One

Calcyclin Binding Protein/Siah-1 Interacting Protein Is a Hsp90 Binding Chaperone

(2016) Agnieszka Góral et al.   PLoS One

The muscle-specific chaperone protein melusin is a potent cardioprotective agent

(2015) Guido Tarone et al.   BASIC RESEARCH IN CARDIOLOGY

Specific Binding of Tetratricopeptide Repeat Proteins to Heat Shock Protein 70 (Hsp70) and Heat Shock Protein 90 (Hsp90) Is Regulated by Affinity and Phosphorylation

(2015) Victoria A. Assimon et al.   BIOCHEMISTRY

Identification of proteins associated with Aha1 in HeLa cells by quantitative proteomics

(2015) Liang Sun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

WISp39 binds phosphorylated Coronin 1B to regulate Arp2/3 localization and Cofilin-dependent motility

(2015) Michael Howell et al.   JOURNAL OF CELL BIOLOGY

c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells

(2015) Diana M. Dunn et al.   Cell Reports

Glucocorticoid Receptor Function Regulated by Coordinated Action of the Hsp90 and Hsp70 Chaperone Cycles

(2014) Elaine Kirschke et al.   CELL

A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways

(2014) Mikko Taipale et al.   CELL

Molecular Chaperone Activity and Biological Regulatory Actions of the TPR-Domain Immunophilins FKBP51 and FKBP52

(2014) Alejandra G. Erlejman et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

The Assembly and Intermolecular Properties of the Hsp70-Tomm34-Hsp90 Molecular Chaperone Complex

(2014) Filip Trcka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Cochaperone SGTA (Small Glutamine-rich Tetratricopeptide Repeat-containing Protein Alpha) Demonstrates Regulatory Specificity for the Androgen, Glucocorticoid, and Progesterone Receptors

(2014) Atanu Paul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm

(2014) Fenglan Dong et al.   JOURNAL OF CELL BIOLOGY

Modulation of the Hsp90 Chaperone Cycle by a Stringent Client Protein

(2014) Oliver Robin Lorenz et al.   MOLECULAR CELL

HSP90α plays an important role in piRNA biogenesis and retrotransposon repression in mouse

(2014) Tomoko Ichiyanagi et al.   NUCLEIC ACIDS RESEARCH

Fnip1 regulates skeletal muscle fiber type specification, fatigue resistance, and susceptibility to muscular dystrophy

(2014) Nicholas L. Reyes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease

(2014) Marc Brehme et al.   Cell Reports

Identification of PDCL3 as a Novel Chaperone Protein Involved in the Generation of Functional VEGF Receptor 2

(2013) Srimathi Srinivasan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heat Shock Protein 90 Functions to Stabilize and Activate the Testis-specific Serine/Threonine Kinases, a Family of Kinases Essential for Male Fertility

(2013) Kula N. Jha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the TPR Domain of AIP: Lack of Client Protein Interaction with the C-Terminal α-7 Helix of the TPR Domain of AIP Is Sufficient for Pituitary Adenoma Predisposition

(2013) Rhodri M. L. Morgan et al.   PLoS One

Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

(2012) Mikko Taipale et al.   CELL

Hsp90 and its co-chaperone, Sgt1, as autoantigens in dilated cardiomyopathy

(2012) Lyudmila L. Kapustian et al.   HEART AND VESSELS

Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis

(2012) Pradeep S. Tanwar et al.   HUMAN MOLECULAR GENETICS

Activation of ras-dependent signaling pathways by G14-coupled receptors requires the adaptor protein TPR1

(2012) Dawna H.T. Kwan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The ‘active life’ of Hsp90 complexes

(2011) Chrisostomos Prodromou   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Post-translational modifications of Hsp90 and their contributions to chaperone regulation

(2011) Mehdi Mollapour et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Morgana and melusin: Two fairies chaperoning signal transduction

(2011) Roberta Ferretti et al.   CELL CYCLE

Structural Features and Chaperone Activity of the NudC Protein Family

(2011) Meiying Zheng et al.   JOURNAL OF MOLECULAR BIOLOGY

Global Functional Map of the p23 Molecular Chaperone Reveals an Extensive Cellular Network

(2011) Frank J. Echtenkamp et al.   MOLECULAR CELL

The Molecular Chaperone Hsp90α Is Required for Meiotic Progression of Spermatocytes beyond Pachytene in the Mouse

(2011) Iwona Grad et al.   PLoS One

An Interaction Network Predicted from Public Data as a Discovery Tool: Application to the Hsp90 Molecular Chaperone Machine

(2011) Pablo C. Echeverría et al.   PLoS One

Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells

(2011) J. T. De Leon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specific Regulation of Noncanonical p38α Activation by Hsp90-Cdc37 Chaperone Complex in Cardiomyocyte

(2010) Asuka Ota et al.   CIRCULATION RESEARCH

Morgana/chp-1, a ROCK Inhibitor Involved in Centrosome Duplication and Tumorigenesis

(2010) Roberta Ferretti et al.   DEVELOPMENTAL CELL

The L279P Mutation of Nuclear Distribution Gene C (NudC) Influences Its Chaperone Activity and Lissencephaly Protein 1 (LIS1) Stability

(2010) Xiao-Jing Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discrete PIH proteins function in the cytoplasmic preassembly of different subsets of axonemal dyneins

(2010) Ryosuke Yamamoto et al.   JOURNAL OF CELL BIOLOGY

FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt

(2009) Huadong Pei et al.   CANCER CELL

Expression of Hsp90 chaperome proteins in human tumor tissue

(2009) Christina L. McDowell et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

A novel role for DYX1C1, a chaperone protein for both Hsp70 and Hsp90, in breast cancer

(2009) Yuxin Chen et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

The HSP90-SGT1 Chaperone Complex for NLR Immune Sensors

(2008) Ken Shirasu   Annual Review of Plant Biology

Role of the Cochaperone Tpr2 in Hsp90 Chaperoning†

(2008) Nela S. Cintrón Moffatt et al.   BIOCHEMISTRY

The role of serine/threonine protein phosphatase type 5 (PP5) in the regulation of stress-induced signaling networks and cancer

(2008) Teresa Golden et al.   CANCER AND METASTASIS REVIEWS

Plasticity of the Hsp90 chaperone machine in divergent eukaryotic organisms

(2008) Jill L. Johnson et al.   CELL STRESS & CHAPERONES

FKBP36 Is an Inherent Multifunctional Glyceraldehyde-3-phosphate Dehydrogenase Inhibitor

(2008) Franziska Jarczowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GCUNC45 Is the First Hsp90 Co-chaperone to Show α/β Isoform Specificity

(2008) Ahmed Chadli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p23/Sba1p Protects against Hsp90 Inhibitors Independently of Its Intrinsic Chaperone Activity

(2008) F. Forafonov et al.   MOLECULAR AND CELLULAR BIOLOGY

Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors

(2008) J R Smith et al.   ONCOGENE

The Human TPR Protein TTC4 Is a Putative Hsp90 Co-Chaperone Which Interacts with CDC6 and Shows Alterations in Transformed Cells

(2008) Gilles Crevel et al.   PLoS One

Unc45b Forms a Cytosolic Complex with Hsp90 and Targets the Unfolded Myosin Motor Domain

(2008) Rajani Srikakulam et al.   PLoS One