Network-based gene prediction for Plasmodium falciparum malaria towards genetics-based drug discovery

Malaria Immunity in Man and Mosquito: Insights into Unsolved Mysteries of a Deadly Infectious Disease

(2014) Peter D. Crompton et al.   Annual Review of Immunology

PTEX is an essential nexus for protein export in malaria parasites

(2014) Brendan Elsworth et al.   NATURE

PTEX component HSP101 mediates export of diverse malaria effectors into host erythrocytes

(2014) Josh R. Beck et al.   NATURE

Recent advances in malaria drug discovery

(2013) Marco A. Biamonte et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Molecular Architecture of a Complex between an Adhesion Protein from the Malaria Parasite and Intracellular Adhesion Molecule 1

(2013) Alan Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Using Mutagenesis and Structural Biology to Map the Binding Site for thePlasmodium falciparumMerozoite Protein PfRh4 on the Human Immune Adherence Receptor

(2013) Hyon Ju Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serum lipids and lipoproteins in malaria - a systematic review and meta-analysis

(2013) Benjamin J Visser et al.   MALARIA JOURNAL

Molecular secrets of a parasite

(2013) Swaminathan Venkatesh et al.   NATURE

Severe malaria is associated with parasite binding to endothelial protein C receptor

(2013) Louise Turner et al.   NATURE

Mast cells fuel the fire of malaria immunopathology

(2013) Christian R Engwerda et al.   NATURE MEDICINE

Malaria biology and disease pathogenesis: insights for new treatments

(2013) Louis H Miller et al.   NATURE MEDICINE

Looking under the skin: the first steps in malarial infection and immunity

(2013) Robert Ménard et al.   NATURE REVIEWS MICROBIOLOGY

Antimalarial drug discovery — approaches and progress towards new medicines

(2013) Erika L. Flannery et al.   NATURE REVIEWS MICROBIOLOGY

How malaria modulates memory: activation and dysregulation of B cells in Plasmodium infection

(2013) Anja Scholzen et al.   TRENDS IN PARASITOLOGY

Malaria parasite liver stages render host hepatocytes susceptible to mitochondria-initiated apoptosis

(2013) A Kaushansky et al.   Cell Death & Disease

Suppression of Host p53 Is Critical for Plasmodium Liver-Stage Infection

(2013) Alexis Kaushansky et al.   Cell Reports

Genetic Variability in Platelet Integrin α2β1 Density: Possible Contributor to Plasmodium vivax–induced Severe Thrombocytopenia

(2012) Fernanda M. F. Campos et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Polymorphisms and expression of TLR4 and 9 in malaria in two ethnic groups of Assam, northeast India

(2012) Clara E Sawian et al.   Innate Immunity

A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies

(2012) A. Bengtsson et al.   JOURNAL OF IMMUNOLOGY

Monocytes and macrophages in malaria: protection or pathology?

(2012) Caroline Lin Lin Chua et al.   TRENDS IN PARASITOLOGY

Enhancing Blockade of Plasmodium falciparum Erythrocyte Invasion: Assessing Combinations of Antibodies against PfRH5 and Other Merozoite Antigens

(2012) Andrew R. Williams et al.   PLoS Pathogens

Neuroimmunological Blood Brain Barrier Opening in Experimental Cerebral Malaria

(2012) Adela Nacer et al.   PLoS Pathogens

Network-based methods for human disease gene prediction

(2011) X. Wang et al.   Briefings in Functional Genomics

Activation of a PAK-MEK signalling pathway in malaria parasite-infected erythrocytes

(2011) Audrey Sicard et al.   CELLULAR MICROBIOLOGY

Population genetics of malaria resistance in humans

(2011) P W Hedrick   HEREDITY

Genetic polymorphisms linked to susceptibility to malaria

(2011) Adel Driss et al.   MALARIA JOURNAL

Investigating the Host Binding Signature on the Plasmodium falciparum PfEMP1 Protein Family

(2011) Joel H. Janes et al.   PLoS Pathogens

Revealing the molecular signatures of host-pathogen interactions

(2011) Chiea-Chuen Khor et al.   GENOME BIOLOGY

Genome-wide inferring gene–phenotype relationship by walking on the heterogeneous network

(2010) Yongjin Li et al.   BIOINFORMATICS

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

Associating Genes and Protein Complexes with Disease via Network Propagation

(2010) Oron Vanunu et al.   PLoS Computational Biology

Complement Receptor 1 Is a Sialic Acid-Independent Erythrocyte Receptor of Plasmodium falciparum

(2010) Carmenza Spadafora et al.   PLoS Pathogens

Plasmodium falciparum-infected erythrocytes induce NF- B regulated inflammatory pathways in human cerebral endothelium

(2009) A. K. Tripathi et al.   BLOOD

Antibodies to Reticulocyte Binding Protein-Like Homologue 4 Inhibit Invasion of Plasmodium falciparum into Human Erythrocytes

(2009) W.-H. Tham et al.   INFECTION AND IMMUNITY

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic and genomic analyses of host-pathogen interactions in malaria

(2009) Silayuv E. Bongfen et al.   TRENDS IN PARASITOLOGY

Significant Association Between TIM1 Promoter Polymorphisms and Protection Against Cerebral Malaria in Thailand

(2008) P. Nuchnoi et al.   ANNALS OF HUMAN GENETICS

Align human interactome with phenome to identify causative genes and networks underlying disease families

(2008) Xuebing Wu et al.   BIOINFORMATICS

PfEMP1: An antigen that plays a key role in the pathogenicity and immune evasion of the malaria parasite Plasmodium falciparum

(2008) Noa D. Pasternak et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Pyruvate Kinase Deficiency and Malaria

(2008) Kodjo Ayi et al.   NEW ENGLAND JOURNAL OF MEDICINE