Align human interactome with phenome to identify causative genes and networks underlying disease families

Walking the Interactome for Prioritization of Candidate Disease Genes

(2008) Sebastian Köhler et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Shedded neuronal ICAM-5 suppresses T-cell activation

(2008) L. Tian et al.   BLOOD

ICAM-5—A novel two-facetted adhesion molecule in the mammalian brain

(2008) Carl G. Gahmberg et al.   IMMUNOLOGY LETTERS

Network-based global inference of human disease genes

(2008) Xuebing Wu et al.   Molecular Systems Biology

Variations in DNA elucidate molecular networks that cause disease

(2008) Yanqing Chen et al.   NATURE

A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans

(2008) Insuk Lee et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

Global alignment of multiple protein interaction networks with application to functional orthology detection

(2008) R. Singh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prediction of Human Disease Genes by Human-Mouse Conserved Coexpression Analysis

(2008) Ugo Ala et al.   PLoS Computational Biology