Anti-cancer agent 3-bromopyruvate reduces growth of MPNST and inhibits metabolic pathways in a representative in-vitro model

Metabolic changes related to the IDH1 mutation in gliomas preserve TCA‐cycle activity: An investigation at the protein level

(2020) Lennard J. M. Dekker et al.   FASEB JOURNAL

Lactate Dehydrogenases as Metabolic Links between Tumor and Stroma in the Tumor Microenvironment

(2019) Deepshikha Mishra et al.   Cancers

MEK inhibitors enhance therapeutic response towards ATRA in NF1 associated malignant peripheral nerve sheath tumors (MPNST) in-vitro

(2017) Susan Fischer-Huchzermeyer et al.   PLoS One

Evaluation of 18F-FDG PET and MRI in differentiating benign and malignant peripheral nerve sheath tumors

(2016) Stephen M. Broski et al.   SKELETAL RADIOLOGY

Evidence for anti-apoptotic roles of proteasome activator 28γ via inhibiting caspase activity

(2015) Anja Moncsek et al.   APOPTOSIS

Deprive to kill

(2012) Simone Cardaci et al.   Autophagy

MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors

(2012) Kivanç Birsoy et al.   NATURE GENETICS

Mitochondrial dysfunction and effect of antiglycolytic bromopyruvic acid in GL15 glioblastoma cells

(2011) Lara Macchioni et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Targeting cancer metabolism: a therapeutic window opens

(2011) Matthew G. Vander Heiden   NATURE REVIEWS DRUG DISCOVERY

Persistent anti-tumor effects via recombinant adeno-associated virus encoding herpes thymidine kinase gene monitored by PET-imaging

(2011) Lee   ONCOLOGY REPORTS

Cancer Stem Cell-Like Cells Derived from Malignant Peripheral Nerve Sheath Tumors

(2011) Melanie Spyra et al.   PLoS One

The Warburg and Crabtree effects: On the origin of cancer cell energy metabolism and of yeast glucose repression

(2010) Rodrigo Diaz-Ruiz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

REGγ modulates p53 activity by regulating its cellular localization

(2010) Jian Liu et al.   JOURNAL OF CELL SCIENCE

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

(2010) A. Le et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate

(2009) Zhao Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Glycolysis: a bioenergetic or a survival pathway?

(2009) Juan P. Bolaños et al.   TRENDS IN BIOCHEMICAL SCIENCES

Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate1

(2008) Ana Paula Pereira Da Silva et al.   BIOCHEMICAL JOURNAL

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Role of reactive oxygen species-mediated mitochondrial dysregulation in 3-bromopyruvate induced cell death in hepatoma cells

(2008) Ji Su Kim et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Loss of cardiolipin in palmitate-treated GL15 glioblastoma cells favors cytochrome c release from mitochondria leading to apoptosis

(2008) Morena Buratta et al.   JOURNAL OF NEUROCHEMISTRY